In vitro effect of experimental nanocomposites solutions on the prevention of dental caries around orthodontic brackets
Abstract This study aimed to evaluate the in vitro effect of a single application of experimental nanocomposite solutions on the prevention of dental caries around orthodontic brackets. The specimens were exposed to mesoporous silica (MS) nanocomposites containing fluoride by association with titanium tetrafluoride (TiF4) or sodium fluoride (NaF). Nanocomposites also could contain calcium and groups were described as MSCaTiF4, MSTiF4, MSCaNaF, MSNaF, and controls (TiF4, and NaF). Specimens were subjected to the formation of a multispecies biofilm to generate a cariogenic challenge. After 24h, both pH and total soluble fluoride concentration of the culture medium were assessed. Mineral loss was evaluated by percentage of surface mineral loss (%SML), mineral volume variation (ΔZ) of inner enamel and polarized light microscopy (PL). Linear (Ra) and volumetric (Sa) surface roughness and scanning electronic microscopy (SEM) were used to assess enamel topography. Statistical analyses were conducted considering p<0.05. MSNaF had the highest value of culture medium pH after cariogenic challenge, similarly to MSTiF4. All nanocomposite solutions released less fluoride than their controls NaF and TiF4 (p<0.05). All nanocomposite solutions presented lower %SML compared to their respective control groups (p<0.05). Lower Ra, Sa and ΔZ were observed for experimental groups compared to TiF4 (p<0.05). The results were confirmed by PL and SEM analysis. The experimental nanocomposite solutions contributed for lower enamel demineralization around orthodontic brackets.
Main Authors: | , , , , , , , , , , , |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Fundação Odontológica de Ribeirão Preto
2021
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402021000400062 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
oai:scielo:S0103-64402021000400062 |
---|---|
record_format |
ojs |
spelling |
oai:scielo:S0103-644020210004000622021-11-09In vitro effect of experimental nanocomposites solutions on the prevention of dental caries around orthodontic bracketsLeite,Karla Lorene de FrançaVieira,Thiago IsidroAlexandria,Adílis KalinaSilva,Raphael Ferreira daSilva,Aline Saddock de SáLopes,Ricardo TadeuFonseca-Gonçalves,AndréaNeves,Aline de AlmeidaCabral,Lúcio MendesPithon,Matheus MeloCavalcanti,Yuri WanderleyMaia,Lucianne Cople Nanotechnology Fluorides Orthodontic Brackets Dental Biofilm Abstract This study aimed to evaluate the in vitro effect of a single application of experimental nanocomposite solutions on the prevention of dental caries around orthodontic brackets. The specimens were exposed to mesoporous silica (MS) nanocomposites containing fluoride by association with titanium tetrafluoride (TiF4) or sodium fluoride (NaF). Nanocomposites also could contain calcium and groups were described as MSCaTiF4, MSTiF4, MSCaNaF, MSNaF, and controls (TiF4, and NaF). Specimens were subjected to the formation of a multispecies biofilm to generate a cariogenic challenge. After 24h, both pH and total soluble fluoride concentration of the culture medium were assessed. Mineral loss was evaluated by percentage of surface mineral loss (%SML), mineral volume variation (ΔZ) of inner enamel and polarized light microscopy (PL). Linear (Ra) and volumetric (Sa) surface roughness and scanning electronic microscopy (SEM) were used to assess enamel topography. Statistical analyses were conducted considering p<0.05. MSNaF had the highest value of culture medium pH after cariogenic challenge, similarly to MSTiF4. All nanocomposite solutions released less fluoride than their controls NaF and TiF4 (p<0.05). All nanocomposite solutions presented lower %SML compared to their respective control groups (p<0.05). Lower Ra, Sa and ΔZ were observed for experimental groups compared to TiF4 (p<0.05). The results were confirmed by PL and SEM analysis. The experimental nanocomposite solutions contributed for lower enamel demineralization around orthodontic brackets.info:eu-repo/semantics/openAccessFundação Odontológica de Ribeirão PretoBrazilian Dental Journal v.32 n.4 20212021-08-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402021000400062en10.1590/0103-6440202104331 |
institution |
SCIELO |
collection |
OJS |
country |
Brasil |
countrycode |
BR |
component |
Revista |
access |
En linea |
databasecode |
rev-scielo-br |
tag |
revista |
region |
America del Sur |
libraryname |
SciELO |
language |
English |
format |
Digital |
author |
Leite,Karla Lorene de França Vieira,Thiago Isidro Alexandria,Adílis Kalina Silva,Raphael Ferreira da Silva,Aline Saddock de Sá Lopes,Ricardo Tadeu Fonseca-Gonçalves,Andréa Neves,Aline de Almeida Cabral,Lúcio Mendes Pithon,Matheus Melo Cavalcanti,Yuri Wanderley Maia,Lucianne Cople |
spellingShingle |
Leite,Karla Lorene de França Vieira,Thiago Isidro Alexandria,Adílis Kalina Silva,Raphael Ferreira da Silva,Aline Saddock de Sá Lopes,Ricardo Tadeu Fonseca-Gonçalves,Andréa Neves,Aline de Almeida Cabral,Lúcio Mendes Pithon,Matheus Melo Cavalcanti,Yuri Wanderley Maia,Lucianne Cople In vitro effect of experimental nanocomposites solutions on the prevention of dental caries around orthodontic brackets |
author_facet |
Leite,Karla Lorene de França Vieira,Thiago Isidro Alexandria,Adílis Kalina Silva,Raphael Ferreira da Silva,Aline Saddock de Sá Lopes,Ricardo Tadeu Fonseca-Gonçalves,Andréa Neves,Aline de Almeida Cabral,Lúcio Mendes Pithon,Matheus Melo Cavalcanti,Yuri Wanderley Maia,Lucianne Cople |
author_sort |
Leite,Karla Lorene de França |
title |
In vitro effect of experimental nanocomposites solutions on the prevention of dental caries around orthodontic brackets |
title_short |
In vitro effect of experimental nanocomposites solutions on the prevention of dental caries around orthodontic brackets |
title_full |
In vitro effect of experimental nanocomposites solutions on the prevention of dental caries around orthodontic brackets |
title_fullStr |
In vitro effect of experimental nanocomposites solutions on the prevention of dental caries around orthodontic brackets |
title_full_unstemmed |
In vitro effect of experimental nanocomposites solutions on the prevention of dental caries around orthodontic brackets |
title_sort |
in vitro effect of experimental nanocomposites solutions on the prevention of dental caries around orthodontic brackets |
description |
Abstract This study aimed to evaluate the in vitro effect of a single application of experimental nanocomposite solutions on the prevention of dental caries around orthodontic brackets. The specimens were exposed to mesoporous silica (MS) nanocomposites containing fluoride by association with titanium tetrafluoride (TiF4) or sodium fluoride (NaF). Nanocomposites also could contain calcium and groups were described as MSCaTiF4, MSTiF4, MSCaNaF, MSNaF, and controls (TiF4, and NaF). Specimens were subjected to the formation of a multispecies biofilm to generate a cariogenic challenge. After 24h, both pH and total soluble fluoride concentration of the culture medium were assessed. Mineral loss was evaluated by percentage of surface mineral loss (%SML), mineral volume variation (ΔZ) of inner enamel and polarized light microscopy (PL). Linear (Ra) and volumetric (Sa) surface roughness and scanning electronic microscopy (SEM) were used to assess enamel topography. Statistical analyses were conducted considering p<0.05. MSNaF had the highest value of culture medium pH after cariogenic challenge, similarly to MSTiF4. All nanocomposite solutions released less fluoride than their controls NaF and TiF4 (p<0.05). All nanocomposite solutions presented lower %SML compared to their respective control groups (p<0.05). Lower Ra, Sa and ΔZ were observed for experimental groups compared to TiF4 (p<0.05). The results were confirmed by PL and SEM analysis. The experimental nanocomposite solutions contributed for lower enamel demineralization around orthodontic brackets. |
publisher |
Fundação Odontológica de Ribeirão Preto |
publishDate |
2021 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402021000400062 |
work_keys_str_mv |
AT leitekarlalorenedefranca invitroeffectofexperimentalnanocompositessolutionsonthepreventionofdentalcariesaroundorthodonticbrackets AT vieirathiagoisidro invitroeffectofexperimentalnanocompositessolutionsonthepreventionofdentalcariesaroundorthodonticbrackets AT alexandriaadiliskalina invitroeffectofexperimentalnanocompositessolutionsonthepreventionofdentalcariesaroundorthodonticbrackets AT silvaraphaelferreirada invitroeffectofexperimentalnanocompositessolutionsonthepreventionofdentalcariesaroundorthodonticbrackets AT silvaalinesaddockdesa invitroeffectofexperimentalnanocompositessolutionsonthepreventionofdentalcariesaroundorthodonticbrackets AT lopesricardotadeu invitroeffectofexperimentalnanocompositessolutionsonthepreventionofdentalcariesaroundorthodonticbrackets AT fonsecagoncalvesandrea invitroeffectofexperimentalnanocompositessolutionsonthepreventionofdentalcariesaroundorthodonticbrackets AT nevesalinedealmeida invitroeffectofexperimentalnanocompositessolutionsonthepreventionofdentalcariesaroundorthodonticbrackets AT cabralluciomendes invitroeffectofexperimentalnanocompositessolutionsonthepreventionofdentalcariesaroundorthodonticbrackets AT pithonmatheusmelo invitroeffectofexperimentalnanocompositessolutionsonthepreventionofdentalcariesaroundorthodonticbrackets AT cavalcantiyuriwanderley invitroeffectofexperimentalnanocompositessolutionsonthepreventionofdentalcariesaroundorthodonticbrackets AT maialuciannecople invitroeffectofexperimentalnanocompositessolutionsonthepreventionofdentalcariesaroundorthodonticbrackets |
_version_ |
1756404644991467520 |