Intercalation of Apocarotenoids from Annatto (Bixa orellana L.) into Layered Double Hydroxides
Synthetic conditions were evaluated to intercalate norbixin into layered double hydroxides (LDH). Norbixin was isolated from a hydrosoluble commercial annatto extract. LDH samples comprising M2+/Al3+ (M = Mg, Zn) were synthesized by coprecipitation and characterized by X-ray diffraction, thermal analysis coupled to mass spectrometry, vibrational spectroscopies, and solid-state 13C nuclear magnetic resonance. Radical scavenging activity of LDH hybrids was monitored by electron paramagnetic resonance towards the stable radical DPPH (1,1-diphenyl-2-picrylhydrazyl). LDH hosts presented more than 50 wt.% of norbixin and d-spacing (003) values of about 2.5 or 3.0 nm depending of the cation LDH composition. Vibrational spectra assignment (supported by density functional theory calculations) confirmed the chemical integrity of norbixin after intercalation into LDH. The inorganic layers were found to enhance the thermal stability of norbixin upon intercalation. The free radical scavenging capacity of norbixin was retained when immobilized into LDH. Considering that zinc and magnesium-LDH matrices are biocompatible and that norbixin presents biological activity, the hybrid materials appear as promising systems for biomedical assessment.
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Sociedade Brasileira de Química
2020
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oai:scielo:S0103-505320200011022112020-10-27Intercalation of Apocarotenoids from Annatto (Bixa orellana L.) into Layered Double HydroxidesPerotti,Gustavo F.Silva,Felipe F.Couto,Ricardo A. A. deLima,Filipe C. D. A.Petrilli,Helena M.Leroux,FabriceFerreira,Ana M. C.Constantino,Vera R. L. hydrotalcite intercalation compounds layered materials norbixin radical scavenging activity Synthetic conditions were evaluated to intercalate norbixin into layered double hydroxides (LDH). Norbixin was isolated from a hydrosoluble commercial annatto extract. LDH samples comprising M2+/Al3+ (M = Mg, Zn) were synthesized by coprecipitation and characterized by X-ray diffraction, thermal analysis coupled to mass spectrometry, vibrational spectroscopies, and solid-state 13C nuclear magnetic resonance. Radical scavenging activity of LDH hybrids was monitored by electron paramagnetic resonance towards the stable radical DPPH (1,1-diphenyl-2-picrylhydrazyl). LDH hosts presented more than 50 wt.% of norbixin and d-spacing (003) values of about 2.5 or 3.0 nm depending of the cation LDH composition. Vibrational spectra assignment (supported by density functional theory calculations) confirmed the chemical integrity of norbixin after intercalation into LDH. The inorganic layers were found to enhance the thermal stability of norbixin upon intercalation. The free radical scavenging capacity of norbixin was retained when immobilized into LDH. Considering that zinc and magnesium-LDH matrices are biocompatible and that norbixin presents biological activity, the hybrid materials appear as promising systems for biomedical assessment.info:eu-repo/semantics/openAccessSociedade Brasileira de QuímicaJournal of the Brazilian Chemical Society v.31 n.11 20202020-11-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532020001102211en10.21577/0103-5053.20200065 |
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Perotti,Gustavo F. Silva,Felipe F. Couto,Ricardo A. A. de Lima,Filipe C. D. A. Petrilli,Helena M. Leroux,Fabrice Ferreira,Ana M. C. Constantino,Vera R. L. |
spellingShingle |
Perotti,Gustavo F. Silva,Felipe F. Couto,Ricardo A. A. de Lima,Filipe C. D. A. Petrilli,Helena M. Leroux,Fabrice Ferreira,Ana M. C. Constantino,Vera R. L. Intercalation of Apocarotenoids from Annatto (Bixa orellana L.) into Layered Double Hydroxides |
author_facet |
Perotti,Gustavo F. Silva,Felipe F. Couto,Ricardo A. A. de Lima,Filipe C. D. A. Petrilli,Helena M. Leroux,Fabrice Ferreira,Ana M. C. Constantino,Vera R. L. |
author_sort |
Perotti,Gustavo F. |
title |
Intercalation of Apocarotenoids from Annatto (Bixa orellana L.) into Layered Double Hydroxides |
title_short |
Intercalation of Apocarotenoids from Annatto (Bixa orellana L.) into Layered Double Hydroxides |
title_full |
Intercalation of Apocarotenoids from Annatto (Bixa orellana L.) into Layered Double Hydroxides |
title_fullStr |
Intercalation of Apocarotenoids from Annatto (Bixa orellana L.) into Layered Double Hydroxides |
title_full_unstemmed |
Intercalation of Apocarotenoids from Annatto (Bixa orellana L.) into Layered Double Hydroxides |
title_sort |
intercalation of apocarotenoids from annatto (bixa orellana l.) into layered double hydroxides |
description |
Synthetic conditions were evaluated to intercalate norbixin into layered double hydroxides (LDH). Norbixin was isolated from a hydrosoluble commercial annatto extract. LDH samples comprising M2+/Al3+ (M = Mg, Zn) were synthesized by coprecipitation and characterized by X-ray diffraction, thermal analysis coupled to mass spectrometry, vibrational spectroscopies, and solid-state 13C nuclear magnetic resonance. Radical scavenging activity of LDH hybrids was monitored by electron paramagnetic resonance towards the stable radical DPPH (1,1-diphenyl-2-picrylhydrazyl). LDH hosts presented more than 50 wt.% of norbixin and d-spacing (003) values of about 2.5 or 3.0 nm depending of the cation LDH composition. Vibrational spectra assignment (supported by density functional theory calculations) confirmed the chemical integrity of norbixin after intercalation into LDH. The inorganic layers were found to enhance the thermal stability of norbixin upon intercalation. The free radical scavenging capacity of norbixin was retained when immobilized into LDH. Considering that zinc and magnesium-LDH matrices are biocompatible and that norbixin presents biological activity, the hybrid materials appear as promising systems for biomedical assessment. |
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Sociedade Brasileira de Química |
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2020 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532020001102211 |
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