Electrochemiluminescence Sensor for the Detection of Tiapride Hydrochloride with Chitosan-Ru(bpy)32+-SiO2NPs/MCNT/Nafion Modified Electrode
Chitosan-Ru2(bpy)32+-SiO2 composite nanoparticles (CRuS NPs) were prepared by reverse microemulsion method for the electronic attraction between negative charge of hydroxyl groups in chitosan and positive charge in Ru2(bpy)3 2+. Based on the multi-walled carbon nanotubes (MCNT)/Nafion composite membrane technology, CRuS NPs was effectively and steadily immobilized on the surface of a glassy carbon electrode. The CRuS NPs synthesized were characterized by transmission electron microscope (TEM), UV-Vis spectroscopy and fluorescence spectroscopy, while the modification was confirmed by cyclic voltammetry and electrogenerated chemiluminescence (ECL). The ECL studies revealed that the sensor had a good response to different concentrations of tiapride hydrochloride and the increased ECL intensity was directly related to the logarithm of tiapride hydrochloride concentrations in the range from 0.01 to 3.0 µmol L-1 with a detection limit of 6.0 nmol L-1. The sensor was successfully applied to the determination of tiapride hydrochloride in pharmaceutical.
Main Authors: | , , , , , , , |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Sociedade Brasileira de Química
2017
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532017000200277 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
oai:scielo:S0103-50532017000200277 |
---|---|
record_format |
ojs |
spelling |
oai:scielo:S0103-505320170002002772017-01-10Electrochemiluminescence Sensor for the Detection of Tiapride Hydrochloride with Chitosan-Ru(bpy)32+-SiO2NPs/MCNT/Nafion Modified ElectrodeFan,XuemeiWang,ShuminLi,ZhejianLiu,PingYu,YanChang,LiangliangLi,KaibinZheng,Xingwang electrogenerated chemiluminescence chitosan tiapride hydrochloride Chitosan-Ru2(bpy)32+-SiO2 composite nanoparticles (CRuS NPs) were prepared by reverse microemulsion method for the electronic attraction between negative charge of hydroxyl groups in chitosan and positive charge in Ru2(bpy)3 2+. Based on the multi-walled carbon nanotubes (MCNT)/Nafion composite membrane technology, CRuS NPs was effectively and steadily immobilized on the surface of a glassy carbon electrode. The CRuS NPs synthesized were characterized by transmission electron microscope (TEM), UV-Vis spectroscopy and fluorescence spectroscopy, while the modification was confirmed by cyclic voltammetry and electrogenerated chemiluminescence (ECL). The ECL studies revealed that the sensor had a good response to different concentrations of tiapride hydrochloride and the increased ECL intensity was directly related to the logarithm of tiapride hydrochloride concentrations in the range from 0.01 to 3.0 µmol L-1 with a detection limit of 6.0 nmol L-1. The sensor was successfully applied to the determination of tiapride hydrochloride in pharmaceutical.info:eu-repo/semantics/openAccessSociedade Brasileira de QuímicaJournal of the Brazilian Chemical Society v.28 n.2 20172017-02-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532017000200277en10.5935/0103-5053.20160174 |
institution |
SCIELO |
collection |
OJS |
country |
Brasil |
countrycode |
BR |
component |
Revista |
access |
En linea |
databasecode |
rev-scielo-br |
tag |
revista |
region |
America del Sur |
libraryname |
SciELO |
language |
English |
format |
Digital |
author |
Fan,Xuemei Wang,Shumin Li,Zhejian Liu,Ping Yu,Yan Chang,Liangliang Li,Kaibin Zheng,Xingwang |
spellingShingle |
Fan,Xuemei Wang,Shumin Li,Zhejian Liu,Ping Yu,Yan Chang,Liangliang Li,Kaibin Zheng,Xingwang Electrochemiluminescence Sensor for the Detection of Tiapride Hydrochloride with Chitosan-Ru(bpy)32+-SiO2NPs/MCNT/Nafion Modified Electrode |
author_facet |
Fan,Xuemei Wang,Shumin Li,Zhejian Liu,Ping Yu,Yan Chang,Liangliang Li,Kaibin Zheng,Xingwang |
author_sort |
Fan,Xuemei |
title |
Electrochemiluminescence Sensor for the Detection of Tiapride Hydrochloride with Chitosan-Ru(bpy)32+-SiO2NPs/MCNT/Nafion Modified Electrode |
title_short |
Electrochemiluminescence Sensor for the Detection of Tiapride Hydrochloride with Chitosan-Ru(bpy)32+-SiO2NPs/MCNT/Nafion Modified Electrode |
title_full |
Electrochemiluminescence Sensor for the Detection of Tiapride Hydrochloride with Chitosan-Ru(bpy)32+-SiO2NPs/MCNT/Nafion Modified Electrode |
title_fullStr |
Electrochemiluminescence Sensor for the Detection of Tiapride Hydrochloride with Chitosan-Ru(bpy)32+-SiO2NPs/MCNT/Nafion Modified Electrode |
title_full_unstemmed |
Electrochemiluminescence Sensor for the Detection of Tiapride Hydrochloride with Chitosan-Ru(bpy)32+-SiO2NPs/MCNT/Nafion Modified Electrode |
title_sort |
electrochemiluminescence sensor for the detection of tiapride hydrochloride with chitosan-ru(bpy)32+-sio2nps/mcnt/nafion modified electrode |
description |
Chitosan-Ru2(bpy)32+-SiO2 composite nanoparticles (CRuS NPs) were prepared by reverse microemulsion method for the electronic attraction between negative charge of hydroxyl groups in chitosan and positive charge in Ru2(bpy)3 2+. Based on the multi-walled carbon nanotubes (MCNT)/Nafion composite membrane technology, CRuS NPs was effectively and steadily immobilized on the surface of a glassy carbon electrode. The CRuS NPs synthesized were characterized by transmission electron microscope (TEM), UV-Vis spectroscopy and fluorescence spectroscopy, while the modification was confirmed by cyclic voltammetry and electrogenerated chemiluminescence (ECL). The ECL studies revealed that the sensor had a good response to different concentrations of tiapride hydrochloride and the increased ECL intensity was directly related to the logarithm of tiapride hydrochloride concentrations in the range from 0.01 to 3.0 µmol L-1 with a detection limit of 6.0 nmol L-1. The sensor was successfully applied to the determination of tiapride hydrochloride in pharmaceutical. |
publisher |
Sociedade Brasileira de Química |
publishDate |
2017 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532017000200277 |
work_keys_str_mv |
AT fanxuemei electrochemiluminescencesensorforthedetectionoftiapridehydrochloridewithchitosanrubpy32sio2npsmcntnafionmodifiedelectrode AT wangshumin electrochemiluminescencesensorforthedetectionoftiapridehydrochloridewithchitosanrubpy32sio2npsmcntnafionmodifiedelectrode AT lizhejian electrochemiluminescencesensorforthedetectionoftiapridehydrochloridewithchitosanrubpy32sio2npsmcntnafionmodifiedelectrode AT liuping electrochemiluminescencesensorforthedetectionoftiapridehydrochloridewithchitosanrubpy32sio2npsmcntnafionmodifiedelectrode AT yuyan electrochemiluminescencesensorforthedetectionoftiapridehydrochloridewithchitosanrubpy32sio2npsmcntnafionmodifiedelectrode AT changliangliang electrochemiluminescencesensorforthedetectionoftiapridehydrochloridewithchitosanrubpy32sio2npsmcntnafionmodifiedelectrode AT likaibin electrochemiluminescencesensorforthedetectionoftiapridehydrochloridewithchitosanrubpy32sio2npsmcntnafionmodifiedelectrode AT zhengxingwang electrochemiluminescencesensorforthedetectionoftiapridehydrochloridewithchitosanrubpy32sio2npsmcntnafionmodifiedelectrode |
_version_ |
1756403674707394560 |