Modified silica nanoparticles with an Aminonaphthoquinone

Modified silica nanoparticles with an Aminonaphthoquinone

The synthesis and characterization of silica nanoparticles (NPs) covalently modified with an aminonaphthoquinone are reported. The aminopropylsilicagelnaphthoquinone (APSGNQ) was obtained by nucleophilic substitution of 2-methoxy-1,4-naphthoquinone with aminopropylsilicalgel (APSG) NPs. Solid state 13C and 29Si nuclear magnetic resonance spectra confirmed that the naphthoquinone is covalently bonded to APSG. Due to the solubility of APSGNQ in common organic solvents, solution ultraviolet-visible spectroscopy was used to determine the amount of naphthoquinone on the NPs surface (0.56 mmol of incorporated naphthoquinone per gram of APSGNQ) by comparison with the spectrum of 2-aminobutyl-1,4-naphthoquinone (ABNQ). Elemental analysis indicated that about 8% of the surface propylamine remained unreacted in APSGNQ. These multifunctional silica NPs have potential in medical applications.

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Main Authors: Silveira,Gleiciani Q, Ronconi,Célia M, Vargas,Maria D, San Gil,Rosane A. S, Magalhães,Alvicler
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Química 2011
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532011000500021
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spelling oai:scielo:S0103-505320110005000212011-05-16Modified silica nanoparticles with an AminonaphthoquinoneSilveira,Gleiciani QRonconi,Célia MVargas,Maria DSan Gil,Rosane A. SMagalhães,Alvicler multifunctional material silica nanoparticles naphthoquinones solid state 13C and 29Si NMR The synthesis and characterization of silica nanoparticles (NPs) covalently modified with an aminonaphthoquinone are reported. The aminopropylsilicagelnaphthoquinone (APSGNQ) was obtained by nucleophilic substitution of 2-methoxy-1,4-naphthoquinone with aminopropylsilicalgel (APSG) NPs. Solid state 13C and 29Si nuclear magnetic resonance spectra confirmed that the naphthoquinone is covalently bonded to APSG. Due to the solubility of APSGNQ in common organic solvents, solution ultraviolet-visible spectroscopy was used to determine the amount of naphthoquinone on the NPs surface (0.56 mmol of incorporated naphthoquinone per gram of APSGNQ) by comparison with the spectrum of 2-aminobutyl-1,4-naphthoquinone (ABNQ). Elemental analysis indicated that about 8% of the surface propylamine remained unreacted in APSGNQ. These multifunctional silica NPs have potential in medical applications.info:eu-repo/semantics/openAccessSociedade Brasileira de QuímicaJournal of the Brazilian Chemical Society v.22 n.5 20112011-05-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532011000500021en10.1590/S0103-50532011000500021
institution SCIELO
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country Brasil
countrycode BR
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access En linea
databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Silveira,Gleiciani Q
Ronconi,Célia M
Vargas,Maria D
San Gil,Rosane A. S
Magalhães,Alvicler
spellingShingle Silveira,Gleiciani Q
Ronconi,Célia M
Vargas,Maria D
San Gil,Rosane A. S
Magalhães,Alvicler
Modified silica nanoparticles with an Aminonaphthoquinone
author_facet Silveira,Gleiciani Q
Ronconi,Célia M
Vargas,Maria D
San Gil,Rosane A. S
Magalhães,Alvicler
author_sort Silveira,Gleiciani Q
title Modified silica nanoparticles with an Aminonaphthoquinone
title_short Modified silica nanoparticles with an Aminonaphthoquinone
title_full Modified silica nanoparticles with an Aminonaphthoquinone
title_fullStr Modified silica nanoparticles with an Aminonaphthoquinone
title_full_unstemmed Modified silica nanoparticles with an Aminonaphthoquinone
title_sort modified silica nanoparticles with an aminonaphthoquinone
description The synthesis and characterization of silica nanoparticles (NPs) covalently modified with an aminonaphthoquinone are reported. The aminopropylsilicagelnaphthoquinone (APSGNQ) was obtained by nucleophilic substitution of 2-methoxy-1,4-naphthoquinone with aminopropylsilicalgel (APSG) NPs. Solid state 13C and 29Si nuclear magnetic resonance spectra confirmed that the naphthoquinone is covalently bonded to APSG. Due to the solubility of APSGNQ in common organic solvents, solution ultraviolet-visible spectroscopy was used to determine the amount of naphthoquinone on the NPs surface (0.56 mmol of incorporated naphthoquinone per gram of APSGNQ) by comparison with the spectrum of 2-aminobutyl-1,4-naphthoquinone (ABNQ). Elemental analysis indicated that about 8% of the surface propylamine remained unreacted in APSGNQ. These multifunctional silica NPs have potential in medical applications.
publisher Sociedade Brasileira de Química
publishDate 2011
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532011000500021
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