Nitric oxide as an activation agent for nucleophilic attack in trans-[Ru(NO)(NH3)4{P(OEt)3}](PF6)3
The complex trans-[Ru(NO)(NH3)4{P(OEt)3}](PF6)3 undergoes nucleophilic attack on the phosphorus ester ligand in the solid state yielding trans-[Ru(NO)(NH3)4{P(OH)(OEt)2}](PF6)3. The reaction was monitored and the products analyzed using nuclear magnetic resonance spectroscopy (31P{¹H} CP-MAS NMR and 31P{¹H} NMR), infrared spectroscopy (FTIR), electron paramagnetic resonance spectroscopy (EPR), cyclic voltammetry (CV), electronic spectroscopy (UV-Vis) and elemental analysis. According to experimental data and quantum mechanical calculations (DFT), the reaction proceeds in the solid state by the nucleophilic attack on the phosphorus ligand, promoted by the strong polarization along the P III-RuII-NO+ axis induced by the nitrosyl ligand, and takes place following the Michaelis-Arbusov type mechanism for phosphorus ester hydrolysis. In solution, the nucleophilic attack occurs simultaneously at the nitrosyl and triethylphosphite ligands, yielding trans-[Ru(H2O)(NH3)4{P(OEt)3}]2+ and trans-[Ru(NO)(H2O)(NH3)4]3+ in comparable amounts.
Main Authors: | Metzker,Gustavo, Toledo Jr.,José C., Lima,Francisco C. A., Magalhães,Alvicler, Cardoso,Daniel R., Franco,Douglas W. |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Sociedade Brasileira de Química
2010
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532010000700014 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
GELATION OF N3P3[NH(CH2)3Si(OEt)3]6-n [X]n X = NH(CH2)3Si(OEt)3, NCH3(CH2)3CN AND OC6H4(CH2)CN, n = 0 or 3 at the LIQUID/AIR/INTERFACE
by: DÍAZ,CARLOS, et al.
Published: (2010) -
Effects of Rut-bpy (Cis-[Ru(bpy)2(SO3)(NO)]PF 6), a novel nitric oxide donor, in L-NAME-induced hypertension in rats
by: Campelo,Marcio Wilker Soares, et al.
Published: (2011) -
Ring transformation of chromone-3-carboxamide under nucleophilic conditions
by: Ibrahim,Magdy A.
Published: (2013) -
Photochemical and Electrochemical Study of the Release of Nitric Oxide from [Ru(bpy)2L(NO)](PF6)n Complexes (L = Imidazole, 1-Methylimidazole, Sulfite and Thiourea), Toward the Development of Therapeutic Photodynamic Agents
by: Cândido,Manuela C. L., et al.
Published: (2015) - OET AL DIA