Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaric

Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaric

A method of bulk liquid membrane (BLM) using O, O'-dibenzoyl-(2S, 3S)-tartaric acid was developed for the enantioselective transport of racemic clenbuterol. The influence of buffer pH, concentration ratio of chiral carrier to clenbuterol were studied. It was an appropriate choice of such as pH 7 in aqueous solution and concentration ratio of 1:4. The model of kinetic transport was established by means of a kinetic model involving two consecutive irreversible first order reactions. The pseudo-first order apparent rate constants were determined. It is helpful for optimizing the transport of BLM systems and realizing the large-scale production of pure enantiomer.

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Main Authors: Jiao,Feipeng, Chen,Xiaoqing, Hu,Weiguo, Yang,Ling, Huang,Kelong
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Química 2007
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000400020
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spelling oai:scielo:S0103-505320070004000202007-09-18Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaricJiao,FeipengChen,XiaoqingHu,WeiguoYang,LingHuang,Kelong bulk liquid membrane enantioselective transport clenbuterol O, O'-dibenzoyl-(2S, 3S)-tartaric acid kinetics A method of bulk liquid membrane (BLM) using O, O'-dibenzoyl-(2S, 3S)-tartaric acid was developed for the enantioselective transport of racemic clenbuterol. The influence of buffer pH, concentration ratio of chiral carrier to clenbuterol were studied. It was an appropriate choice of such as pH 7 in aqueous solution and concentration ratio of 1:4. The model of kinetic transport was established by means of a kinetic model involving two consecutive irreversible first order reactions. The pseudo-first order apparent rate constants were determined. It is helpful for optimizing the transport of BLM systems and realizing the large-scale production of pure enantiomer.info:eu-repo/semantics/openAccessSociedade Brasileira de QuímicaJournal of the Brazilian Chemical Society v.18 n.4 20072007-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000400020en10.1590/S0103-50532007000400020
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Jiao,Feipeng
Chen,Xiaoqing
Hu,Weiguo
Yang,Ling
Huang,Kelong
spellingShingle Jiao,Feipeng
Chen,Xiaoqing
Hu,Weiguo
Yang,Ling
Huang,Kelong
Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaric
author_facet Jiao,Feipeng
Chen,Xiaoqing
Hu,Weiguo
Yang,Ling
Huang,Kelong
author_sort Jiao,Feipeng
title Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaric
title_short Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaric
title_full Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaric
title_fullStr Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaric
title_full_unstemmed Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaric
title_sort enantioselective transport of r-clenbuterol through a bulk liquid membrane containing o,o'-dibenzoyl-(2s, 3s)-tartaric
description A method of bulk liquid membrane (BLM) using O, O'-dibenzoyl-(2S, 3S)-tartaric acid was developed for the enantioselective transport of racemic clenbuterol. The influence of buffer pH, concentration ratio of chiral carrier to clenbuterol were studied. It was an appropriate choice of such as pH 7 in aqueous solution and concentration ratio of 1:4. The model of kinetic transport was established by means of a kinetic model involving two consecutive irreversible first order reactions. The pseudo-first order apparent rate constants were determined. It is helpful for optimizing the transport of BLM systems and realizing the large-scale production of pure enantiomer.
publisher Sociedade Brasileira de Química
publishDate 2007
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000400020
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AT chenxiaoqing enantioselectivetransportofrclenbuterolthroughabulkliquidmembranecontainingoodibenzoyl2s3startaric
AT huweiguo enantioselectivetransportofrclenbuterolthroughabulkliquidmembranecontainingoodibenzoyl2s3startaric
AT yangling enantioselectivetransportofrclenbuterolthroughabulkliquidmembranecontainingoodibenzoyl2s3startaric
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