A new natural auaternary indole slkaloid isolated from Tabernaemontana laeta Mart. (Apocynaceae)

A new natural quaternary alkaloid, Nb-methylvoachalotine (1), was obtained from the root bark of Tabernaemontana laeta together with three dimeric indole alkaloids, conodurine (2), voacamine (3) and tabernamine (4), and the monomeric indole alkaloids 19S-heyneanine (5), coronaridine (6) and voacangine (7). The known triterpenes alpha-amyrin acetate, beta-amyrin acetate, lupeol acetate and taraxasterol acetate and the phytosterol beta-sitosterol and its 3-O-beta-D-glucoside were also identified. The structures of the compounds were elucidated based on spectroscopic studies.

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Main Authors: Medeiros,Walter L. B., Vieira,Ivo José C., Mathias,Leda, Braz-Filho,Raimundo, Schripsema,Jan
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Química 2001
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532001000300008
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spelling oai:scielo:S0103-505320010003000082001-10-02A new natural auaternary indole slkaloid isolated from Tabernaemontana laeta Mart. (Apocynaceae)Medeiros,Walter L. B.Vieira,Ivo José C.Mathias,LedaBraz-Filho,RaimundoSchripsema,Jan Tabernaemontana laeta Apocynaceae indole-alkaloids triterpenes A new natural quaternary alkaloid, Nb-methylvoachalotine (1), was obtained from the root bark of Tabernaemontana laeta together with three dimeric indole alkaloids, conodurine (2), voacamine (3) and tabernamine (4), and the monomeric indole alkaloids 19S-heyneanine (5), coronaridine (6) and voacangine (7). The known triterpenes alpha-amyrin acetate, beta-amyrin acetate, lupeol acetate and taraxasterol acetate and the phytosterol beta-sitosterol and its 3-O-beta-D-glucoside were also identified. The structures of the compounds were elucidated based on spectroscopic studies.info:eu-repo/semantics/openAccessSociedade Brasileira de QuímicaJournal of the Brazilian Chemical Society v.12 n.3 20012001-06-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532001000300008en10.1590/S0103-50532001000300008
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country Brasil
countrycode BR
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databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Medeiros,Walter L. B.
Vieira,Ivo José C.
Mathias,Leda
Braz-Filho,Raimundo
Schripsema,Jan
spellingShingle Medeiros,Walter L. B.
Vieira,Ivo José C.
Mathias,Leda
Braz-Filho,Raimundo
Schripsema,Jan
A new natural auaternary indole slkaloid isolated from Tabernaemontana laeta Mart. (Apocynaceae)
author_facet Medeiros,Walter L. B.
Vieira,Ivo José C.
Mathias,Leda
Braz-Filho,Raimundo
Schripsema,Jan
author_sort Medeiros,Walter L. B.
title A new natural auaternary indole slkaloid isolated from Tabernaemontana laeta Mart. (Apocynaceae)
title_short A new natural auaternary indole slkaloid isolated from Tabernaemontana laeta Mart. (Apocynaceae)
title_full A new natural auaternary indole slkaloid isolated from Tabernaemontana laeta Mart. (Apocynaceae)
title_fullStr A new natural auaternary indole slkaloid isolated from Tabernaemontana laeta Mart. (Apocynaceae)
title_full_unstemmed A new natural auaternary indole slkaloid isolated from Tabernaemontana laeta Mart. (Apocynaceae)
title_sort new natural auaternary indole slkaloid isolated from tabernaemontana laeta mart. (apocynaceae)
description A new natural quaternary alkaloid, Nb-methylvoachalotine (1), was obtained from the root bark of Tabernaemontana laeta together with three dimeric indole alkaloids, conodurine (2), voacamine (3) and tabernamine (4), and the monomeric indole alkaloids 19S-heyneanine (5), coronaridine (6) and voacangine (7). The known triterpenes alpha-amyrin acetate, beta-amyrin acetate, lupeol acetate and taraxasterol acetate and the phytosterol beta-sitosterol and its 3-O-beta-D-glucoside were also identified. The structures of the compounds were elucidated based on spectroscopic studies.
publisher Sociedade Brasileira de Química
publishDate 2001
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532001000300008
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