Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs
Abstract Purpose: To analyze the anesthetic drugs interference with wound healing when used in the surgical bed. Methods: Macro and microscopic aspects of healing of surgical wounds were evaluated after instillation of topical anesthetics without vasoconstrictor or saline solution 0.9% as control in the transsurgical period. Thirty dogs, males and females were divided into two experimental groups. In both groups, two circular punch lesions of 6 mm diameter were performed in the abdomen. In group 1, lidocaine was instilled in one of the lesions and saline solution in the contralateral lesion. In group 2 the procedure was repeated with the use of bupivacaine. The macroscopic assessment of the lesions was performed on the first, third and tenth postoperative day. The excisional biopsy was performed on the tenth day and the samples were submitted for histopathological examination. Results: The macroscopic analysis had a significant difference between groups. Microscopic analysis was not significant between groups. Conclusions: The topical application of lidocaine and bupivacaine in the surgical wound is feasible and it does not influence skin healing. The benefit of such a practice, which has been the subject of other studies, seems to outweigh the risks.
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Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
2020
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oai:scielo:S0102-865020200007002022020-08-11Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogsMinto,Bruno WatanabeZanato,LauraFranco,Guilherme GalhardoKawamoto,Fernando Yoiti KitamuraBorsaro,Camila PotérioPazzini,Josiane MoraisCarvalho,Elizabeth ReginaMatsui,Andresa Surgical Wounds Lidocaine Bupivacaine Analgesia Dogs Abstract Purpose: To analyze the anesthetic drugs interference with wound healing when used in the surgical bed. Methods: Macro and microscopic aspects of healing of surgical wounds were evaluated after instillation of topical anesthetics without vasoconstrictor or saline solution 0.9% as control in the transsurgical period. Thirty dogs, males and females were divided into two experimental groups. In both groups, two circular punch lesions of 6 mm diameter were performed in the abdomen. In group 1, lidocaine was instilled in one of the lesions and saline solution in the contralateral lesion. In group 2 the procedure was repeated with the use of bupivacaine. The macroscopic assessment of the lesions was performed on the first, third and tenth postoperative day. The excisional biopsy was performed on the tenth day and the samples were submitted for histopathological examination. Results: The macroscopic analysis had a significant difference between groups. Microscopic analysis was not significant between groups. Conclusions: The topical application of lidocaine and bupivacaine in the surgical wound is feasible and it does not influence skin healing. The benefit of such a practice, which has been the subject of other studies, seems to outweigh the risks.info:eu-repo/semantics/openAccessSociedade Brasileira para o Desenvolvimento da Pesquisa em CirurgiaActa Cirúrgica Brasileira v.35 n.7 20202020-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502020000700202en10.1590/s0102-865020200070000001 |
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Minto,Bruno Watanabe Zanato,Laura Franco,Guilherme Galhardo Kawamoto,Fernando Yoiti Kitamura Borsaro,Camila Potério Pazzini,Josiane Morais Carvalho,Elizabeth Regina Matsui,Andresa |
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Minto,Bruno Watanabe Zanato,Laura Franco,Guilherme Galhardo Kawamoto,Fernando Yoiti Kitamura Borsaro,Camila Potério Pazzini,Josiane Morais Carvalho,Elizabeth Regina Matsui,Andresa Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs |
author_facet |
Minto,Bruno Watanabe Zanato,Laura Franco,Guilherme Galhardo Kawamoto,Fernando Yoiti Kitamura Borsaro,Camila Potério Pazzini,Josiane Morais Carvalho,Elizabeth Regina Matsui,Andresa |
author_sort |
Minto,Bruno Watanabe |
title |
Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs |
title_short |
Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs |
title_full |
Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs |
title_fullStr |
Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs |
title_full_unstemmed |
Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs |
title_sort |
topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs |
description |
Abstract Purpose: To analyze the anesthetic drugs interference with wound healing when used in the surgical bed. Methods: Macro and microscopic aspects of healing of surgical wounds were evaluated after instillation of topical anesthetics without vasoconstrictor or saline solution 0.9% as control in the transsurgical period. Thirty dogs, males and females were divided into two experimental groups. In both groups, two circular punch lesions of 6 mm diameter were performed in the abdomen. In group 1, lidocaine was instilled in one of the lesions and saline solution in the contralateral lesion. In group 2 the procedure was repeated with the use of bupivacaine. The macroscopic assessment of the lesions was performed on the first, third and tenth postoperative day. The excisional biopsy was performed on the tenth day and the samples were submitted for histopathological examination. Results: The macroscopic analysis had a significant difference between groups. Microscopic analysis was not significant between groups. Conclusions: The topical application of lidocaine and bupivacaine in the surgical wound is feasible and it does not influence skin healing. The benefit of such a practice, which has been the subject of other studies, seems to outweigh the risks. |
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Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
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2020 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502020000700202 |
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