Use of cyanoacrylate-based surgical adhesives associated to the macroporous tape in skin synthesis in rats
Abstract Purpose: To compare the use of new cyanoacrylate surgical adhesive associated with macroporous tapes in cutaneous synthesis. Methods: Male Wistar rats with a longitudinal incision of 4cm were used on the back, divided into four groups: GI used octyl-cyanoacrylate (Dermabond®), GII used N-2-butylcyanoacrylate, GIII used octyl-cyanoacrylate and macroporous tape and GIV used N-2-butyl cyanoacrylate and macroporous tape. On the fourteenth day, the rats were submitted to euthanasia, were divided in two parts, and a layer of skin subcutaneous tissue through an area of operative healing was removed. One part was submitted to the study of rupture strength with the use of tensiometer, and in the other part histological examination was performed. Results: No force test was similar between groups I and II, being different from groups III and IV (P <0.001), which were identical to each other (P> 0.05). The units were compared among the studied groups, and they were different with the use of macroporous tapes (P> 0.05). Conclusions: The purpose of macroporous tapes is associated with CA adhesives in cutaneous tissues that provide more resistant scars. The use of a combination of macroporous tapes leads to complete re-epithelialization, without provoking foreign body reaction, has hemostatic properties and does not cause an absorptive reaction.
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Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
2019
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oai:scielo:S0102-865020190007002002019-09-09Use of cyanoacrylate-based surgical adhesives associated to the macroporous tape in skin synthesis in ratsIlgenfritz Neto,JoãoAydos,Ricardo DutraSilva,Iandara SchettertTakita,Luiz CarlosAbreu,Antônio Carlos deSilva,Cynthia Alexia CunhaFaleiros,Karina BossiSantiago,Evair Moisés de LimaRamalho,Rondon Tosta Adhesives Cyanoacrylates Rats, Wistar Abstract Purpose: To compare the use of new cyanoacrylate surgical adhesive associated with macroporous tapes in cutaneous synthesis. Methods: Male Wistar rats with a longitudinal incision of 4cm were used on the back, divided into four groups: GI used octyl-cyanoacrylate (Dermabond®), GII used N-2-butylcyanoacrylate, GIII used octyl-cyanoacrylate and macroporous tape and GIV used N-2-butyl cyanoacrylate and macroporous tape. On the fourteenth day, the rats were submitted to euthanasia, were divided in two parts, and a layer of skin subcutaneous tissue through an area of operative healing was removed. One part was submitted to the study of rupture strength with the use of tensiometer, and in the other part histological examination was performed. Results: No force test was similar between groups I and II, being different from groups III and IV (P <0.001), which were identical to each other (P> 0.05). The units were compared among the studied groups, and they were different with the use of macroporous tapes (P> 0.05). Conclusions: The purpose of macroporous tapes is associated with CA adhesives in cutaneous tissues that provide more resistant scars. The use of a combination of macroporous tapes leads to complete re-epithelialization, without provoking foreign body reaction, has hemostatic properties and does not cause an absorptive reaction.info:eu-repo/semantics/openAccessSociedade Brasileira para o Desenvolvimento da Pesquisa em CirurgiaActa Cirúrgica Brasileira v.34 n.7 20192019-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502019000700200en10.1590/s0102-865020190070000001 |
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Ilgenfritz Neto,João Aydos,Ricardo Dutra Silva,Iandara Schettert Takita,Luiz Carlos Abreu,Antônio Carlos de Silva,Cynthia Alexia Cunha Faleiros,Karina Bossi Santiago,Evair Moisés de Lima Ramalho,Rondon Tosta |
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Ilgenfritz Neto,João Aydos,Ricardo Dutra Silva,Iandara Schettert Takita,Luiz Carlos Abreu,Antônio Carlos de Silva,Cynthia Alexia Cunha Faleiros,Karina Bossi Santiago,Evair Moisés de Lima Ramalho,Rondon Tosta Use of cyanoacrylate-based surgical adhesives associated to the macroporous tape in skin synthesis in rats |
author_facet |
Ilgenfritz Neto,João Aydos,Ricardo Dutra Silva,Iandara Schettert Takita,Luiz Carlos Abreu,Antônio Carlos de Silva,Cynthia Alexia Cunha Faleiros,Karina Bossi Santiago,Evair Moisés de Lima Ramalho,Rondon Tosta |
author_sort |
Ilgenfritz Neto,João |
title |
Use of cyanoacrylate-based surgical adhesives associated to the macroporous tape in skin synthesis in rats |
title_short |
Use of cyanoacrylate-based surgical adhesives associated to the macroporous tape in skin synthesis in rats |
title_full |
Use of cyanoacrylate-based surgical adhesives associated to the macroporous tape in skin synthesis in rats |
title_fullStr |
Use of cyanoacrylate-based surgical adhesives associated to the macroporous tape in skin synthesis in rats |
title_full_unstemmed |
Use of cyanoacrylate-based surgical adhesives associated to the macroporous tape in skin synthesis in rats |
title_sort |
use of cyanoacrylate-based surgical adhesives associated to the macroporous tape in skin synthesis in rats |
description |
Abstract Purpose: To compare the use of new cyanoacrylate surgical adhesive associated with macroporous tapes in cutaneous synthesis. Methods: Male Wistar rats with a longitudinal incision of 4cm were used on the back, divided into four groups: GI used octyl-cyanoacrylate (Dermabond®), GII used N-2-butylcyanoacrylate, GIII used octyl-cyanoacrylate and macroporous tape and GIV used N-2-butyl cyanoacrylate and macroporous tape. On the fourteenth day, the rats were submitted to euthanasia, were divided in two parts, and a layer of skin subcutaneous tissue through an area of operative healing was removed. One part was submitted to the study of rupture strength with the use of tensiometer, and in the other part histological examination was performed. Results: No force test was similar between groups I and II, being different from groups III and IV (P <0.001), which were identical to each other (P> 0.05). The units were compared among the studied groups, and they were different with the use of macroporous tapes (P> 0.05). Conclusions: The purpose of macroporous tapes is associated with CA adhesives in cutaneous tissues that provide more resistant scars. The use of a combination of macroporous tapes leads to complete re-epithelialization, without provoking foreign body reaction, has hemostatic properties and does not cause an absorptive reaction. |
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Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
publishDate |
2019 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502019000700200 |
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