Description of a new experimental model skin flap for studying skin viability in rats
PURPOSE: To describe a new experimental flap for studying skin viability in rats.METHODS: Twenty male Wistar rats weighing between 250-300g were divided into two groups: group A - McFarlane technique, a 4 x 10cm flap was used (McFarlane); and in group B modified McFarlane technique, a 3 x 10cm flap was used. Seven days later, the animals were sacrificed and the area of necrosis was evaluated in both groups.RESULTS: Group A presented necrosis in 3% of the total area of the flap (CI: 0.01-0.05), Group B presented necrosis in 37% of the total area of the flap (CI: 0.29-0.46), (p<0.001).CONCLUSION: The modified McFarlane flap presented a larger area of necrosis and could be an adequate experimental model of skin flap viability.
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Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
2014
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oai:scielo:S0102-865020140003001662015-10-26Description of a new experimental model skin flap for studying skin viability in ratsCamargo,Cristina PiresMargarido,Nelson FontanaGuandelini,EduardoVieira,Guilherme Alexandre BarrucciJacomo,Alfredo LuizGemperli,Rolf Surgical Flaps Necrosis Models, Animal Rats PURPOSE: To describe a new experimental flap for studying skin viability in rats.METHODS: Twenty male Wistar rats weighing between 250-300g were divided into two groups: group A - McFarlane technique, a 4 x 10cm flap was used (McFarlane); and in group B modified McFarlane technique, a 3 x 10cm flap was used. Seven days later, the animals were sacrificed and the area of necrosis was evaluated in both groups.RESULTS: Group A presented necrosis in 3% of the total area of the flap (CI: 0.01-0.05), Group B presented necrosis in 37% of the total area of the flap (CI: 0.29-0.46), (p<0.001).CONCLUSION: The modified McFarlane flap presented a larger area of necrosis and could be an adequate experimental model of skin flap viability.info:eu-repo/semantics/openAccessSociedade Brasileira para o Desenvolvimento da Pesquisa em CirurgiaActa Cirúrgica Brasileira v.29 n.3 20142014-03-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502014000300166en10.1590/S0102-86502014000300004 |
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Camargo,Cristina Pires Margarido,Nelson Fontana Guandelini,Eduardo Vieira,Guilherme Alexandre Barrucci Jacomo,Alfredo Luiz Gemperli,Rolf |
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Camargo,Cristina Pires Margarido,Nelson Fontana Guandelini,Eduardo Vieira,Guilherme Alexandre Barrucci Jacomo,Alfredo Luiz Gemperli,Rolf Description of a new experimental model skin flap for studying skin viability in rats |
| author_facet |
Camargo,Cristina Pires Margarido,Nelson Fontana Guandelini,Eduardo Vieira,Guilherme Alexandre Barrucci Jacomo,Alfredo Luiz Gemperli,Rolf |
| author_sort |
Camargo,Cristina Pires |
| title |
Description of a new experimental model skin flap for studying skin viability in rats |
| title_short |
Description of a new experimental model skin flap for studying skin viability in rats |
| title_full |
Description of a new experimental model skin flap for studying skin viability in rats |
| title_fullStr |
Description of a new experimental model skin flap for studying skin viability in rats |
| title_full_unstemmed |
Description of a new experimental model skin flap for studying skin viability in rats |
| title_sort |
description of a new experimental model skin flap for studying skin viability in rats |
| description |
PURPOSE: To describe a new experimental flap for studying skin viability in rats.METHODS: Twenty male Wistar rats weighing between 250-300g were divided into two groups: group A - McFarlane technique, a 4 x 10cm flap was used (McFarlane); and in group B modified McFarlane technique, a 3 x 10cm flap was used. Seven days later, the animals were sacrificed and the area of necrosis was evaluated in both groups.RESULTS: Group A presented necrosis in 3% of the total area of the flap (CI: 0.01-0.05), Group B presented necrosis in 37% of the total area of the flap (CI: 0.29-0.46), (p<0.001).CONCLUSION: The modified McFarlane flap presented a larger area of necrosis and could be an adequate experimental model of skin flap viability. |
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Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
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2014 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502014000300166 |
| work_keys_str_mv |
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1756400944926425088 |