Electric microcurrent in the restoration of the skin undergone a trichloroacetic acid peeling in rats

PURPOSE: To investigate the influence of neuromuscular electric stimulation by microcurrent (MENS - Microcurrent Electric Neuromuscular Stimulation) in the restoration of the skin of rats undergone trichloroacetic acid (TCA). METHODS: Thirty-two hairless, male, adult rats were divided into two groups (with 16 animals each). In the Control Group (G1) the application of microcurrent was simulated 48 hours after the peeling. In the Experimental Group (G2) MENS was applied 48 hours after the TCA peeling, each 48 hours up to the Day 21, under the frequency of 0.5 Hz, intensity of 50mu A, and lasting 20 minutes. The area of the lesion was evaluated on Days 7, 14, and 21 after-peeling by the Paper Template Method, and on Day 21 the histological analysis was performed. RESULTS: On microscopy changes were seen in the fibroblasts amount and structure, and in the collagen of the experimental group, with statistically significant difference (p<0,01) CONCLUSION: MENS reduced the period of restoration of the area undergone TCA peeling in rats skin.

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Main Authors: Santos,Vilma Natividade Silva, Ferreira,Lydia Masako, Horibe,Edith Kawano, Duarte,Ivone da Silva
Format: Digital revista
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2004
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502004000500003
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spelling oai:scielo:S0102-865020040005000032004-11-04Electric microcurrent in the restoration of the skin undergone a trichloroacetic acid peeling in ratsSantos,Vilma Natividade SilvaFerreira,Lydia MasakoHoribe,Edith KawanoDuarte,Ivone da Silva Trichloroacetic acid Wound healing Electric stimulation Chemexfoliation Rats PURPOSE: To investigate the influence of neuromuscular electric stimulation by microcurrent (MENS - Microcurrent Electric Neuromuscular Stimulation) in the restoration of the skin of rats undergone trichloroacetic acid (TCA). METHODS: Thirty-two hairless, male, adult rats were divided into two groups (with 16 animals each). In the Control Group (G1) the application of microcurrent was simulated 48 hours after the peeling. In the Experimental Group (G2) MENS was applied 48 hours after the TCA peeling, each 48 hours up to the Day 21, under the frequency of 0.5 Hz, intensity of 50mu A, and lasting 20 minutes. The area of the lesion was evaluated on Days 7, 14, and 21 after-peeling by the Paper Template Method, and on Day 21 the histological analysis was performed. RESULTS: On microscopy changes were seen in the fibroblasts amount and structure, and in the collagen of the experimental group, with statistically significant difference (p<0,01) CONCLUSION: MENS reduced the period of restoration of the area undergone TCA peeling in rats skin.info:eu-repo/semantics/openAccessSociedade Brasileira para o Desenvolvimento da Pesquisa em CirurgiaActa Cirúrgica Brasileira v.19 n.5 20042004-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502004000500003en10.1590/S0102-86502004000500003
institution SCIELO
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country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Santos,Vilma Natividade Silva
Ferreira,Lydia Masako
Horibe,Edith Kawano
Duarte,Ivone da Silva
spellingShingle Santos,Vilma Natividade Silva
Ferreira,Lydia Masako
Horibe,Edith Kawano
Duarte,Ivone da Silva
Electric microcurrent in the restoration of the skin undergone a trichloroacetic acid peeling in rats
author_facet Santos,Vilma Natividade Silva
Ferreira,Lydia Masako
Horibe,Edith Kawano
Duarte,Ivone da Silva
author_sort Santos,Vilma Natividade Silva
title Electric microcurrent in the restoration of the skin undergone a trichloroacetic acid peeling in rats
title_short Electric microcurrent in the restoration of the skin undergone a trichloroacetic acid peeling in rats
title_full Electric microcurrent in the restoration of the skin undergone a trichloroacetic acid peeling in rats
title_fullStr Electric microcurrent in the restoration of the skin undergone a trichloroacetic acid peeling in rats
title_full_unstemmed Electric microcurrent in the restoration of the skin undergone a trichloroacetic acid peeling in rats
title_sort electric microcurrent in the restoration of the skin undergone a trichloroacetic acid peeling in rats
description PURPOSE: To investigate the influence of neuromuscular electric stimulation by microcurrent (MENS - Microcurrent Electric Neuromuscular Stimulation) in the restoration of the skin of rats undergone trichloroacetic acid (TCA). METHODS: Thirty-two hairless, male, adult rats were divided into two groups (with 16 animals each). In the Control Group (G1) the application of microcurrent was simulated 48 hours after the peeling. In the Experimental Group (G2) MENS was applied 48 hours after the TCA peeling, each 48 hours up to the Day 21, under the frequency of 0.5 Hz, intensity of 50mu A, and lasting 20 minutes. The area of the lesion was evaluated on Days 7, 14, and 21 after-peeling by the Paper Template Method, and on Day 21 the histological analysis was performed. RESULTS: On microscopy changes were seen in the fibroblasts amount and structure, and in the collagen of the experimental group, with statistically significant difference (p<0,01) CONCLUSION: MENS reduced the period of restoration of the area undergone TCA peeling in rats skin.
publisher Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publishDate 2004
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502004000500003
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