Prognosis and Complications of Diabetic Patients Undergoing Isolated Coronary Artery Bypass Surgery

Abstract Objective: Compare the prognosis and complications of diabetic and non-diabetic patients undergoing isolated coronary artery bypass surgery at a hospital with a high surgical volume. Methods: Data of patients who underwent coronary artery bypass surgery from June 2009 to July 2010 were analyzed. We selected diabetic and non-diabetic patients and evaluated their postoperative and long-term prognosis based on clinical complications. To reduce the disparity within the sample, statistical analyses were performed using propensity scores. Results: We included 2,688 patients who underwent coronary artery bypass surgery; 36% of them had diabetes, their mean age was 62.1±9.49 years and 70% (1,884) of them were men. Patients with diabetes were older (63±9 years vs. 61±10 years; P<0.001), more often obese (BMI>25 kg/m2: 70.7% vs.64.5%; P<0.001), dyslipidemic (50.4%vs. 41.1%; P<0.001), hypertensive (89.2% vs. 78.7%; P<0.001), and presented chronic renal failure (8.3% vs. 3.8%;P<0.001). They also presented higher rates of acute renal failure (5.6% vs. 2.7%, P<0.001), infection (11.4% vs. 7.2%, P<0.001) and mortality after one year (9.1% vs. 5.6%,P<0.001). Pneumonia was more common among patients with diabetes (7.7% vs. 4.0%, P<0.001). According to propensity scoring, 430 patients (215 diabetics and 215 non-diabetics) had a mean age of 61.3±8.97 years, and 21.2% (91 of 430) were women. However, diabetes was not an independent factor for poor prognosis. Conclusion: Patients with diabetes were at higher risk for postoperative complications and mortality after undergoing coronary artery bypass surgery. However, diabetes did not explain the poor prognosis of these patients after pairing this factor with the propensity score.

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Main Authors: Santos,Karen Alcantara Queiroz, Berto,Bharbara, Sousa,Alexandre Gonçalves, Costa,Fernando Augusto Alves da
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Cirurgia Cardiovascular 2016
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382016000100007
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spelling oai:scielo:S0102-763820160001000072016-04-04Prognosis and Complications of Diabetic Patients Undergoing Isolated Coronary Artery Bypass SurgerySantos,Karen Alcantara QueirozBerto,BharbaraSousa,Alexandre GonçalvesCosta,Fernando Augusto Alves da Diabetes Mellitus Coronary Artery Bypass Diabetes Complications Cardiac Surgical Procedures Comparative Study. Abstract Objective: Compare the prognosis and complications of diabetic and non-diabetic patients undergoing isolated coronary artery bypass surgery at a hospital with a high surgical volume. Methods: Data of patients who underwent coronary artery bypass surgery from June 2009 to July 2010 were analyzed. We selected diabetic and non-diabetic patients and evaluated their postoperative and long-term prognosis based on clinical complications. To reduce the disparity within the sample, statistical analyses were performed using propensity scores. Results: We included 2,688 patients who underwent coronary artery bypass surgery; 36% of them had diabetes, their mean age was 62.1±9.49 years and 70% (1,884) of them were men. Patients with diabetes were older (63±9 years vs. 61±10 years; P<0.001), more often obese (BMI>25 kg/m2: 70.7% vs.64.5%; P<0.001), dyslipidemic (50.4%vs. 41.1%; P<0.001), hypertensive (89.2% vs. 78.7%; P<0.001), and presented chronic renal failure (8.3% vs. 3.8%;P<0.001). They also presented higher rates of acute renal failure (5.6% vs. 2.7%, P<0.001), infection (11.4% vs. 7.2%, P<0.001) and mortality after one year (9.1% vs. 5.6%,P<0.001). Pneumonia was more common among patients with diabetes (7.7% vs. 4.0%, P<0.001). According to propensity scoring, 430 patients (215 diabetics and 215 non-diabetics) had a mean age of 61.3±8.97 years, and 21.2% (91 of 430) were women. However, diabetes was not an independent factor for poor prognosis. Conclusion: Patients with diabetes were at higher risk for postoperative complications and mortality after undergoing coronary artery bypass surgery. However, diabetes did not explain the poor prognosis of these patients after pairing this factor with the propensity score.info:eu-repo/semantics/openAccessSociedade Brasileira de Cirurgia CardiovascularBrazilian Journal of Cardiovascular Surgery v.31 n.1 20162016-02-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382016000100007en10.5935/1678-9741.20160002
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language English
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author Santos,Karen Alcantara Queiroz
Berto,Bharbara
Sousa,Alexandre Gonçalves
Costa,Fernando Augusto Alves da
spellingShingle Santos,Karen Alcantara Queiroz
Berto,Bharbara
Sousa,Alexandre Gonçalves
Costa,Fernando Augusto Alves da
Prognosis and Complications of Diabetic Patients Undergoing Isolated Coronary Artery Bypass Surgery
author_facet Santos,Karen Alcantara Queiroz
Berto,Bharbara
Sousa,Alexandre Gonçalves
Costa,Fernando Augusto Alves da
author_sort Santos,Karen Alcantara Queiroz
title Prognosis and Complications of Diabetic Patients Undergoing Isolated Coronary Artery Bypass Surgery
title_short Prognosis and Complications of Diabetic Patients Undergoing Isolated Coronary Artery Bypass Surgery
title_full Prognosis and Complications of Diabetic Patients Undergoing Isolated Coronary Artery Bypass Surgery
title_fullStr Prognosis and Complications of Diabetic Patients Undergoing Isolated Coronary Artery Bypass Surgery
title_full_unstemmed Prognosis and Complications of Diabetic Patients Undergoing Isolated Coronary Artery Bypass Surgery
title_sort prognosis and complications of diabetic patients undergoing isolated coronary artery bypass surgery
description Abstract Objective: Compare the prognosis and complications of diabetic and non-diabetic patients undergoing isolated coronary artery bypass surgery at a hospital with a high surgical volume. Methods: Data of patients who underwent coronary artery bypass surgery from June 2009 to July 2010 were analyzed. We selected diabetic and non-diabetic patients and evaluated their postoperative and long-term prognosis based on clinical complications. To reduce the disparity within the sample, statistical analyses were performed using propensity scores. Results: We included 2,688 patients who underwent coronary artery bypass surgery; 36% of them had diabetes, their mean age was 62.1±9.49 years and 70% (1,884) of them were men. Patients with diabetes were older (63±9 years vs. 61±10 years; P<0.001), more often obese (BMI>25 kg/m2: 70.7% vs.64.5%; P<0.001), dyslipidemic (50.4%vs. 41.1%; P<0.001), hypertensive (89.2% vs. 78.7%; P<0.001), and presented chronic renal failure (8.3% vs. 3.8%;P<0.001). They also presented higher rates of acute renal failure (5.6% vs. 2.7%, P<0.001), infection (11.4% vs. 7.2%, P<0.001) and mortality after one year (9.1% vs. 5.6%,P<0.001). Pneumonia was more common among patients with diabetes (7.7% vs. 4.0%, P<0.001). According to propensity scoring, 430 patients (215 diabetics and 215 non-diabetics) had a mean age of 61.3±8.97 years, and 21.2% (91 of 430) were women. However, diabetes was not an independent factor for poor prognosis. Conclusion: Patients with diabetes were at higher risk for postoperative complications and mortality after undergoing coronary artery bypass surgery. However, diabetes did not explain the poor prognosis of these patients after pairing this factor with the propensity score.
publisher Sociedade Brasileira de Cirurgia Cardiovascular
publishDate 2016
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382016000100007
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