Paullinia cupana: a multipurpose plant - a review

Abstract Seeds of guarana (Paullinia cupana Kunth, Sapindaceae) feature diverse pharmacological functions, for example, antimicrobial, antioxidant, anticarcinogenic, stimulating, and cognitive functions, as well as liver protection and weight loss. Many of these actions are probably due to the high content of methylxanthines and tannins in its seeds. In Brazil, the world's largest producer of guarana, the plant material is predominantly used in the soft drinks industry, although it is also used in the cosmetic and pharmaceutical industries. Although the Amazon region has the largest cropping area, the state of Bahia is the main guarana producer in Brazil (71%). This review focuses mainly on the possible pharmacological actions of guarana that have been investigated. Moreover, it discusses less-considered topics, such as the toxicology and quality control of seeds and extractives of guarana that will ultimately influence the safety of its use. In addition, it presents a detailed discussion of the methods used to prepare herbal drugs and their extracts, focusing on the importance of standardization and on the direct impact of preparatory factors, on the pharmacological properties of guarana extracts.

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Main Authors: Marques,Leila Larisa Medeiros, Ferreira,Emilene Dias Fiuza, Paula,Mariana Nascimento de, Klein,Traudi, Mello,João Carlos Palazzo de
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Farmacognosia 2019
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2019000100077
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spelling oai:scielo:S0102-695X20190001000772019-03-29Paullinia cupana: a multipurpose plant - a reviewMarques,Leila Larisa MedeirosFerreira,Emilene Dias FiuzaPaula,Mariana Nascimento deKlein,TraudiMello,João Carlos Palazzo de Guarana Pharmacological properties Quality control Standardization Toxicology Abstract Seeds of guarana (Paullinia cupana Kunth, Sapindaceae) feature diverse pharmacological functions, for example, antimicrobial, antioxidant, anticarcinogenic, stimulating, and cognitive functions, as well as liver protection and weight loss. Many of these actions are probably due to the high content of methylxanthines and tannins in its seeds. In Brazil, the world's largest producer of guarana, the plant material is predominantly used in the soft drinks industry, although it is also used in the cosmetic and pharmaceutical industries. Although the Amazon region has the largest cropping area, the state of Bahia is the main guarana producer in Brazil (71%). This review focuses mainly on the possible pharmacological actions of guarana that have been investigated. Moreover, it discusses less-considered topics, such as the toxicology and quality control of seeds and extractives of guarana that will ultimately influence the safety of its use. In addition, it presents a detailed discussion of the methods used to prepare herbal drugs and their extracts, focusing on the importance of standardization and on the direct impact of preparatory factors, on the pharmacological properties of guarana extracts.info:eu-repo/semantics/openAccessSociedade Brasileira de FarmacognosiaRevista Brasileira de Farmacognosia v.29 n.1 20192019-02-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2019000100077en10.1016/j.bjp.2018.08.007
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country Brasil
countrycode BR
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libraryname SciELO
language English
format Digital
author Marques,Leila Larisa Medeiros
Ferreira,Emilene Dias Fiuza
Paula,Mariana Nascimento de
Klein,Traudi
Mello,João Carlos Palazzo de
spellingShingle Marques,Leila Larisa Medeiros
Ferreira,Emilene Dias Fiuza
Paula,Mariana Nascimento de
Klein,Traudi
Mello,João Carlos Palazzo de
Paullinia cupana: a multipurpose plant - a review
author_facet Marques,Leila Larisa Medeiros
Ferreira,Emilene Dias Fiuza
Paula,Mariana Nascimento de
Klein,Traudi
Mello,João Carlos Palazzo de
author_sort Marques,Leila Larisa Medeiros
title Paullinia cupana: a multipurpose plant - a review
title_short Paullinia cupana: a multipurpose plant - a review
title_full Paullinia cupana: a multipurpose plant - a review
title_fullStr Paullinia cupana: a multipurpose plant - a review
title_full_unstemmed Paullinia cupana: a multipurpose plant - a review
title_sort paullinia cupana: a multipurpose plant - a review
description Abstract Seeds of guarana (Paullinia cupana Kunth, Sapindaceae) feature diverse pharmacological functions, for example, antimicrobial, antioxidant, anticarcinogenic, stimulating, and cognitive functions, as well as liver protection and weight loss. Many of these actions are probably due to the high content of methylxanthines and tannins in its seeds. In Brazil, the world's largest producer of guarana, the plant material is predominantly used in the soft drinks industry, although it is also used in the cosmetic and pharmaceutical industries. Although the Amazon region has the largest cropping area, the state of Bahia is the main guarana producer in Brazil (71%). This review focuses mainly on the possible pharmacological actions of guarana that have been investigated. Moreover, it discusses less-considered topics, such as the toxicology and quality control of seeds and extractives of guarana that will ultimately influence the safety of its use. In addition, it presents a detailed discussion of the methods used to prepare herbal drugs and their extracts, focusing on the importance of standardization and on the direct impact of preparatory factors, on the pharmacological properties of guarana extracts.
publisher Sociedade Brasileira de Farmacognosia
publishDate 2019
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2019000100077
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