C15 acetogenins from the Laurencia complex: 50 years of research – an overview

Abstract Acetogenins are secondary metabolites derived from the polyketide pathway and their potential role as chemotaxonomical markers for red algae belonging to the Laurencia complex has been long pointed out. C15 acetogenins from algae are quite different from plant acetogenins: they are usually halogenated, and have an enyne or a bromoallene terminal group. Since they were first reported, laurencin and other algal acetogenins have inspired great curiosity among natural product chemists and also those working with synthesis. This paper reviews the literature about C15 acetogenins, focusing on their distribution, chemical and biological aspects, including their reported biological activities.

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Main Authors: Wanke,Tauana, Philippus,Ana Cláudia, Zatelli,Gabriele Andressa, Vieira,Lucas Felipe Oliveira, Lhullier,Cintia, Falkenberg,Miriam
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Farmacognosia 2015
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2015000600569
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spelling oai:scielo:S0102-695X20150006005692015-12-22C15 acetogenins from the Laurencia complex: 50 years of research – an overviewWanke,TauanaPhilippus,Ana CláudiaZatelli,Gabriele AndressaVieira,Lucas Felipe OliveiraLhullier,CintiaFalkenberg,Miriam Acetogenins Red algae Laurencia complex Halogenated metabolites Bromoethers Abstract Acetogenins are secondary metabolites derived from the polyketide pathway and their potential role as chemotaxonomical markers for red algae belonging to the Laurencia complex has been long pointed out. C15 acetogenins from algae are quite different from plant acetogenins: they are usually halogenated, and have an enyne or a bromoallene terminal group. Since they were first reported, laurencin and other algal acetogenins have inspired great curiosity among natural product chemists and also those working with synthesis. This paper reviews the literature about C15 acetogenins, focusing on their distribution, chemical and biological aspects, including their reported biological activities.info:eu-repo/semantics/openAccessSociedade Brasileira de FarmacognosiaRevista Brasileira de Farmacognosia v.25 n.6 20152015-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2015000600569en10.1016/j.bjp.2015.07.027
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libraryname SciELO
language English
format Digital
author Wanke,Tauana
Philippus,Ana Cláudia
Zatelli,Gabriele Andressa
Vieira,Lucas Felipe Oliveira
Lhullier,Cintia
Falkenberg,Miriam
spellingShingle Wanke,Tauana
Philippus,Ana Cláudia
Zatelli,Gabriele Andressa
Vieira,Lucas Felipe Oliveira
Lhullier,Cintia
Falkenberg,Miriam
C15 acetogenins from the Laurencia complex: 50 years of research – an overview
author_facet Wanke,Tauana
Philippus,Ana Cláudia
Zatelli,Gabriele Andressa
Vieira,Lucas Felipe Oliveira
Lhullier,Cintia
Falkenberg,Miriam
author_sort Wanke,Tauana
title C15 acetogenins from the Laurencia complex: 50 years of research – an overview
title_short C15 acetogenins from the Laurencia complex: 50 years of research – an overview
title_full C15 acetogenins from the Laurencia complex: 50 years of research – an overview
title_fullStr C15 acetogenins from the Laurencia complex: 50 years of research – an overview
title_full_unstemmed C15 acetogenins from the Laurencia complex: 50 years of research – an overview
title_sort c15 acetogenins from the laurencia complex: 50 years of research – an overview
description Abstract Acetogenins are secondary metabolites derived from the polyketide pathway and their potential role as chemotaxonomical markers for red algae belonging to the Laurencia complex has been long pointed out. C15 acetogenins from algae are quite different from plant acetogenins: they are usually halogenated, and have an enyne or a bromoallene terminal group. Since they were first reported, laurencin and other algal acetogenins have inspired great curiosity among natural product chemists and also those working with synthesis. This paper reviews the literature about C15 acetogenins, focusing on their distribution, chemical and biological aspects, including their reported biological activities.
publisher Sociedade Brasileira de Farmacognosia
publishDate 2015
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2015000600569
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