Estudo fitoquímico de Auxemma glazioviana Taub.
Phytochemical investigation of heartwood of Auxemma glazioviana (Boraginaceae) has led to the isolation of three benzoquinones, one hydroquinone identified as: oncocalyxone A (1), oncocalyxone C (2), glazioviana A (3), glaziovianol (4) besides allantoin (5) α-bisabolol (6) and α-cadinol (7). Their structures were determined based on spectral analysis, including 2D NMR experiments. Essential oil obtained from heartwood by hydrodistillation was analyzed by GC/MS. The major constituents were identified as α-bisabolol and α-cadinol. The oil was active against larvae of dengue (Aedes aegypti ) with DL50 2.98 ppm.
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| Main Authors: | , , , , |
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| Format: | Digital revista |
| Language: | Portuguese |
| Published: |
Sociedade Brasileira de Farmacognosia
2002
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| Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2002000300033 |
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| Summary: | Phytochemical investigation of heartwood of Auxemma glazioviana (Boraginaceae) has led to the isolation of three benzoquinones, one hydroquinone identified as: oncocalyxone A (1), oncocalyxone C (2), glazioviana A (3), glaziovianol (4) besides allantoin (5) α-bisabolol (6) and α-cadinol (7). Their structures were determined based on spectral analysis, including 2D NMR experiments. Essential oil obtained from heartwood by hydrodistillation was analyzed by GC/MS. The major constituents were identified as α-bisabolol and α-cadinol. The oil was active against larvae of dengue (Aedes aegypti ) with DL50 2.98 ppm. |
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