PRELIMINARY DATA ON LIVER TRANSPLANTATION IN HYDATIDOSIS DISEASE
ABSTRACT - BACKGROUND: Hydatidosis is a rare and endemic parasitic disease in Brazil that causes the proliferation of cysts mainly in the liver, leading to many complications, such as compression of vessels and biliary ducts, liver failure, portal hypertension, and cirrhosis. The treatment of choice is the resection of the lesions combined with albendazole therapy. This disease is a rare indication for liver transplantation, a feasible treatment option in more advanced stages. AIM: The purpose of this study was to describe two cases of patients from northern Brazil who underwent liver transplantation due to hepatic hydatidosis. METHODS: This is a retrospective study with data collected from medical records. RESULTS: Case 1: A 51-year-old female patient presented pain in the right hypochondriac, dyspepsia, consumptive syndrome, and obstructive jaundice, with a previous diagnosis of Caroli’s disease with no possibility of surgical resection and a MELD score of 24. She underwent liver transplantation, and the anatomopathological result demonstrated hydatidosis. Case 2: A 52-year-old female patient presented multiple episodes of cholangitis in 30 years, with three liver resections and clinical treatment with albendazole for hydatidosis. She underwent liver transplantation due to recurrent cholangitis with a MELD score of 20. Both patients underwent post-transplant clinical therapy with albendazole, had good outcomes, and remain in follow-up without complications after 5 and 96 months, respectively. CONCLUSION: The patients benefited from the procedure and have a good prognosis due to the absence of metastasis, early reintroduction of antiparasitic drugs, and continuous follow-up.
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Colégio Brasileiro de Cirurgia Digestiva
2022
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oai:scielo:S0102-672020220001003202022-06-22PRELIMINARY DATA ON LIVER TRANSPLANTATION IN HYDATIDOSIS DISEASECASTRO,Alexia Rangel deHYPPOLITO,Elodie BomfimVALENÇA-JÚNIOR,José TelmoCOELHO,Gustavo RegoGARCIA,José Huygens Parente Echinococcosis, Hepatic Liver Transplantation Liver Diseases, Parasitic ABSTRACT - BACKGROUND: Hydatidosis is a rare and endemic parasitic disease in Brazil that causes the proliferation of cysts mainly in the liver, leading to many complications, such as compression of vessels and biliary ducts, liver failure, portal hypertension, and cirrhosis. The treatment of choice is the resection of the lesions combined with albendazole therapy. This disease is a rare indication for liver transplantation, a feasible treatment option in more advanced stages. AIM: The purpose of this study was to describe two cases of patients from northern Brazil who underwent liver transplantation due to hepatic hydatidosis. METHODS: This is a retrospective study with data collected from medical records. RESULTS: Case 1: A 51-year-old female patient presented pain in the right hypochondriac, dyspepsia, consumptive syndrome, and obstructive jaundice, with a previous diagnosis of Caroli’s disease with no possibility of surgical resection and a MELD score of 24. She underwent liver transplantation, and the anatomopathological result demonstrated hydatidosis. Case 2: A 52-year-old female patient presented multiple episodes of cholangitis in 30 years, with three liver resections and clinical treatment with albendazole for hydatidosis. She underwent liver transplantation due to recurrent cholangitis with a MELD score of 20. Both patients underwent post-transplant clinical therapy with albendazole, had good outcomes, and remain in follow-up without complications after 5 and 96 months, respectively. CONCLUSION: The patients benefited from the procedure and have a good prognosis due to the absence of metastasis, early reintroduction of antiparasitic drugs, and continuous follow-up.info:eu-repo/semantics/openAccessColégio Brasileiro de Cirurgia DigestivaABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) v.35 20222022-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202022000100320en10.1590/0102-672020210002e1667 |
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CASTRO,Alexia Rangel de HYPPOLITO,Elodie Bomfim VALENÇA-JÚNIOR,José Telmo COELHO,Gustavo Rego GARCIA,José Huygens Parente |
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CASTRO,Alexia Rangel de HYPPOLITO,Elodie Bomfim VALENÇA-JÚNIOR,José Telmo COELHO,Gustavo Rego GARCIA,José Huygens Parente PRELIMINARY DATA ON LIVER TRANSPLANTATION IN HYDATIDOSIS DISEASE |
author_facet |
CASTRO,Alexia Rangel de HYPPOLITO,Elodie Bomfim VALENÇA-JÚNIOR,José Telmo COELHO,Gustavo Rego GARCIA,José Huygens Parente |
author_sort |
CASTRO,Alexia Rangel de |
title |
PRELIMINARY DATA ON LIVER TRANSPLANTATION IN HYDATIDOSIS DISEASE |
title_short |
PRELIMINARY DATA ON LIVER TRANSPLANTATION IN HYDATIDOSIS DISEASE |
title_full |
PRELIMINARY DATA ON LIVER TRANSPLANTATION IN HYDATIDOSIS DISEASE |
title_fullStr |
PRELIMINARY DATA ON LIVER TRANSPLANTATION IN HYDATIDOSIS DISEASE |
title_full_unstemmed |
PRELIMINARY DATA ON LIVER TRANSPLANTATION IN HYDATIDOSIS DISEASE |
title_sort |
preliminary data on liver transplantation in hydatidosis disease |
description |
ABSTRACT - BACKGROUND: Hydatidosis is a rare and endemic parasitic disease in Brazil that causes the proliferation of cysts mainly in the liver, leading to many complications, such as compression of vessels and biliary ducts, liver failure, portal hypertension, and cirrhosis. The treatment of choice is the resection of the lesions combined with albendazole therapy. This disease is a rare indication for liver transplantation, a feasible treatment option in more advanced stages. AIM: The purpose of this study was to describe two cases of patients from northern Brazil who underwent liver transplantation due to hepatic hydatidosis. METHODS: This is a retrospective study with data collected from medical records. RESULTS: Case 1: A 51-year-old female patient presented pain in the right hypochondriac, dyspepsia, consumptive syndrome, and obstructive jaundice, with a previous diagnosis of Caroli’s disease with no possibility of surgical resection and a MELD score of 24. She underwent liver transplantation, and the anatomopathological result demonstrated hydatidosis. Case 2: A 52-year-old female patient presented multiple episodes of cholangitis in 30 years, with three liver resections and clinical treatment with albendazole for hydatidosis. She underwent liver transplantation due to recurrent cholangitis with a MELD score of 20. Both patients underwent post-transplant clinical therapy with albendazole, had good outcomes, and remain in follow-up without complications after 5 and 96 months, respectively. CONCLUSION: The patients benefited from the procedure and have a good prognosis due to the absence of metastasis, early reintroduction of antiparasitic drugs, and continuous follow-up. |
publisher |
Colégio Brasileiro de Cirurgia Digestiva |
publishDate |
2022 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202022000100320 |
work_keys_str_mv |
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