Evaluation of the effectiveness of platelet-rich plasma in the bone consolidation of patients submitted to lumbar arthrodesis

ABSTRACT OBJECTIVE: To determine whether the use of autograft associated with platelet-rich plasma (PRP) increases bone healing in patients undergoing lumbar fusion. METHOD: This was a prospective, descriptive, and comparative study, which included 40 patients undergoing lumbar fusion, who were divided into two groups: group I, autograft only, and group II, autograft associated with PRP. After surgery, patients were followed-up on the first, third, and sixth month. The Molinari radiographic classification and Glassman tomographic classification were used as criteria to analyze the bone consolidation. RESULT: Comparing the group I with group II, according to the criteria of Molinari, bilateral fusion was observed in 27.5% of the patients in group I in the first month after surgery. In group II, the rate of bilateral fusion was 25.0% and 20% in the third and sixth months, respectively. The results of computed tomography scans performed at six months after surgery indicated, according to the criteria of Glassman, a rate of bilateral solid fusion of 15.0% and 10.0% in groups I and II, respectively. CONCLUSION: The use of PRP showed no significant difference in bone healing in cases of lumbar arthrodesis.

Bibliographic Details

Main Authors:	Rezende,Caroline Ferraz, Azevedo,Danielly de Paula, Lourenço,Rafael Burgomeister, Duarte,José Fernando, Cardoso,Igor Machado, Jacob Júnior,Charbel
Format:	Digital revista
Language:	English
Published:	Sociedade Brasileira de Ortopedia e Traumatologia 2017
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162017000600693
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