The challenges of the pandemic and the vaccination against covid-19 in pediatric patients with kidney disease
ABSTRACT The covid-19 vaccine confers direct protection and reduces transmission rates of the virus and new variants. Vaccines from Pfizer/BioNTech and CoronaVac have been cleared for children in Brazil. They are safe, effective, and immunogenic. There are no known complications associated with the use of steroids or vaccines in pediatric patients with covid-19 and nephrotic syndrome. With or without immunosuppression, these patients are not at increased risk of severe covid-19, and steroids are safe for them. A milder form of covid-19 occurs in patients with chronic kidney disease without the need for hospitalization. The vaccine response may be reduced and/or the duration of antibodies after vaccination may be shorter than in the general population. However, considering risk of exposure, vaccination against covid-19 is recommended. It is believed that patients with hemolytic-uremic syndrome are at higher risk of severe covid-19. Vaccination is recommended, although specific data on the safety and efficacy of the covid-19 vaccine are limited. There is agreement that the benefits of induced immunity outweigh the risks of immunization. Vaccination against covid-19 is recommended for children and adolescents needing kidney transplantation or who have undergone transplantation. These patients present decreased immune response after vaccination, but immunization is recommended because the benefits outweigh the risks of vaccination. Current recommendations in Brazil stipulate the use of the messenger RNA vaccine. This paper aims to provide pediatric nephrologists with the latest knowledge about vaccination against covid-19 for children with kidney disease.
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Sociedade Brasileira de Nefrologia
2022
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oai:scielo:S0101-280020220050544012022-10-20The challenges of the pandemic and the vaccination against covid-19 in pediatric patients with kidney diseaseSoeiro,Emília Maria DantasPenido,Maria Goretti Moreira GuimarãesPalma,Lilian Monteiro PereiraBresolin,Nilzete LiberatoLima,Eduardo Jorge da FonsecaKoch,Vera Hermina KalikaTavares,Marcelo de SousaSylvestre,LucimaryBernardes,Rejane de PaulaGarcia,Clotilde DruckAndrade,Maria Cristina deKaufman,ArnauldChow,Charles Yea ZenMartins,Suelen Bianca StopaCamargo,Suzana Friedlander Del Nero Vaccines Covid-19 Hemolytic-Uremic Syndrome Nephrotic Syndrome Renal Insufficiency Chronic Kidney transplantation ABSTRACT The covid-19 vaccine confers direct protection and reduces transmission rates of the virus and new variants. Vaccines from Pfizer/BioNTech and CoronaVac have been cleared for children in Brazil. They are safe, effective, and immunogenic. There are no known complications associated with the use of steroids or vaccines in pediatric patients with covid-19 and nephrotic syndrome. With or without immunosuppression, these patients are not at increased risk of severe covid-19, and steroids are safe for them. A milder form of covid-19 occurs in patients with chronic kidney disease without the need for hospitalization. The vaccine response may be reduced and/or the duration of antibodies after vaccination may be shorter than in the general population. However, considering risk of exposure, vaccination against covid-19 is recommended. It is believed that patients with hemolytic-uremic syndrome are at higher risk of severe covid-19. Vaccination is recommended, although specific data on the safety and efficacy of the covid-19 vaccine are limited. There is agreement that the benefits of induced immunity outweigh the risks of immunization. Vaccination against covid-19 is recommended for children and adolescents needing kidney transplantation or who have undergone transplantation. These patients present decreased immune response after vaccination, but immunization is recommended because the benefits outweigh the risks of vaccination. Current recommendations in Brazil stipulate the use of the messenger RNA vaccine. This paper aims to provide pediatric nephrologists with the latest knowledge about vaccination against covid-19 for children with kidney disease.info:eu-repo/semantics/openAccessSociedade Brasileira de NefrologiaBrazilian Journal of Nephrology n.ahead 20222022-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002022005054401en10.1590/2175-8239-jbn-2022-0081en |
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Soeiro,Emília Maria Dantas Penido,Maria Goretti Moreira Guimarães Palma,Lilian Monteiro Pereira Bresolin,Nilzete Liberato Lima,Eduardo Jorge da Fonseca Koch,Vera Hermina Kalika Tavares,Marcelo de Sousa Sylvestre,Lucimary Bernardes,Rejane de Paula Garcia,Clotilde Druck Andrade,Maria Cristina de Kaufman,Arnauld Chow,Charles Yea Zen Martins,Suelen Bianca Stopa Camargo,Suzana Friedlander Del Nero |
spellingShingle |
Soeiro,Emília Maria Dantas Penido,Maria Goretti Moreira Guimarães Palma,Lilian Monteiro Pereira Bresolin,Nilzete Liberato Lima,Eduardo Jorge da Fonseca Koch,Vera Hermina Kalika Tavares,Marcelo de Sousa Sylvestre,Lucimary Bernardes,Rejane de Paula Garcia,Clotilde Druck Andrade,Maria Cristina de Kaufman,Arnauld Chow,Charles Yea Zen Martins,Suelen Bianca Stopa Camargo,Suzana Friedlander Del Nero The challenges of the pandemic and the vaccination against covid-19 in pediatric patients with kidney disease |
author_facet |
Soeiro,Emília Maria Dantas Penido,Maria Goretti Moreira Guimarães Palma,Lilian Monteiro Pereira Bresolin,Nilzete Liberato Lima,Eduardo Jorge da Fonseca Koch,Vera Hermina Kalika Tavares,Marcelo de Sousa Sylvestre,Lucimary Bernardes,Rejane de Paula Garcia,Clotilde Druck Andrade,Maria Cristina de Kaufman,Arnauld Chow,Charles Yea Zen Martins,Suelen Bianca Stopa Camargo,Suzana Friedlander Del Nero |
author_sort |
Soeiro,Emília Maria Dantas |
title |
The challenges of the pandemic and the vaccination against covid-19 in pediatric patients with kidney disease |
title_short |
The challenges of the pandemic and the vaccination against covid-19 in pediatric patients with kidney disease |
title_full |
The challenges of the pandemic and the vaccination against covid-19 in pediatric patients with kidney disease |
title_fullStr |
The challenges of the pandemic and the vaccination against covid-19 in pediatric patients with kidney disease |
title_full_unstemmed |
The challenges of the pandemic and the vaccination against covid-19 in pediatric patients with kidney disease |
title_sort |
challenges of the pandemic and the vaccination against covid-19 in pediatric patients with kidney disease |
description |
ABSTRACT The covid-19 vaccine confers direct protection and reduces transmission rates of the virus and new variants. Vaccines from Pfizer/BioNTech and CoronaVac have been cleared for children in Brazil. They are safe, effective, and immunogenic. There are no known complications associated with the use of steroids or vaccines in pediatric patients with covid-19 and nephrotic syndrome. With or without immunosuppression, these patients are not at increased risk of severe covid-19, and steroids are safe for them. A milder form of covid-19 occurs in patients with chronic kidney disease without the need for hospitalization. The vaccine response may be reduced and/or the duration of antibodies after vaccination may be shorter than in the general population. However, considering risk of exposure, vaccination against covid-19 is recommended. It is believed that patients with hemolytic-uremic syndrome are at higher risk of severe covid-19. Vaccination is recommended, although specific data on the safety and efficacy of the covid-19 vaccine are limited. There is agreement that the benefits of induced immunity outweigh the risks of immunization. Vaccination against covid-19 is recommended for children and adolescents needing kidney transplantation or who have undergone transplantation. These patients present decreased immune response after vaccination, but immunization is recommended because the benefits outweigh the risks of vaccination. Current recommendations in Brazil stipulate the use of the messenger RNA vaccine. This paper aims to provide pediatric nephrologists with the latest knowledge about vaccination against covid-19 for children with kidney disease. |
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Sociedade Brasileira de Nefrologia |
publishDate |
2022 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002022005054401 |
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