Rotavirus and reovirus interaction with mouse peritoneal resident phagocytic cells

Rotavirus and reovirus interaction with mouse peritoneal resident phagocytic cells

Rotaviruses and reoviruses are involved in human and animal diseases. It is known that both viruses penetrate the gastrointestinal tract but their interaction with phagocytic cells is unknown. To study this interaction, peritoneal resident phagocytic cells were used and rotavirus and reovirus replication in peritoneal phagocytic cells was observed. However, rotavirus replication in these cells led to the production of defective particles since MA-104 cells inoculated with rotavirus phagocytic cell lysate did not show any evidence of virus replication. On the basis of these results, we suggest that, although reovirus dissemination may be helped by these phagocytic cells, these cells may control rotavirus infection and probably contribute to the prevention of its dissemination.

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Main Authors: Guimarães,M.A.A.M., Nozawa,C.M., Guimarães,A.C.C., Ramos,S.
Format: Digital revista
Language:English
Published: Associação Brasileira de Divulgação Científica 1997
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997001000008
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spelling oai:scielo:S0100-879X19970010000081998-10-07Rotavirus and reovirus interaction with mouse peritoneal resident phagocytic cellsGuimarães,M.A.A.M.Nozawa,C.M.Guimarães,A.C.C.Ramos,S. rotavirus reovirus phagocytic cells Rotaviruses and reoviruses are involved in human and animal diseases. It is known that both viruses penetrate the gastrointestinal tract but their interaction with phagocytic cells is unknown. To study this interaction, peritoneal resident phagocytic cells were used and rotavirus and reovirus replication in peritoneal phagocytic cells was observed. However, rotavirus replication in these cells led to the production of defective particles since MA-104 cells inoculated with rotavirus phagocytic cell lysate did not show any evidence of virus replication. On the basis of these results, we suggest that, although reovirus dissemination may be helped by these phagocytic cells, these cells may control rotavirus infection and probably contribute to the prevention of its dissemination.info:eu-repo/semantics/openAccessAssociação Brasileira de Divulgação CientíficaBrazilian Journal of Medical and Biological Research v.30 n.10 19971997-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997001000008en10.1590/S0100-879X1997001000008
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Guimarães,M.A.A.M.
Nozawa,C.M.
Guimarães,A.C.C.
Ramos,S.
spellingShingle Guimarães,M.A.A.M.
Nozawa,C.M.
Guimarães,A.C.C.
Ramos,S.
Rotavirus and reovirus interaction with mouse peritoneal resident phagocytic cells
author_facet Guimarães,M.A.A.M.
Nozawa,C.M.
Guimarães,A.C.C.
Ramos,S.
author_sort Guimarães,M.A.A.M.
title Rotavirus and reovirus interaction with mouse peritoneal resident phagocytic cells
title_short Rotavirus and reovirus interaction with mouse peritoneal resident phagocytic cells
title_full Rotavirus and reovirus interaction with mouse peritoneal resident phagocytic cells
title_fullStr Rotavirus and reovirus interaction with mouse peritoneal resident phagocytic cells
title_full_unstemmed Rotavirus and reovirus interaction with mouse peritoneal resident phagocytic cells
title_sort rotavirus and reovirus interaction with mouse peritoneal resident phagocytic cells
description Rotaviruses and reoviruses are involved in human and animal diseases. It is known that both viruses penetrate the gastrointestinal tract but their interaction with phagocytic cells is unknown. To study this interaction, peritoneal resident phagocytic cells were used and rotavirus and reovirus replication in peritoneal phagocytic cells was observed. However, rotavirus replication in these cells led to the production of defective particles since MA-104 cells inoculated with rotavirus phagocytic cell lysate did not show any evidence of virus replication. On the basis of these results, we suggest that, although reovirus dissemination may be helped by these phagocytic cells, these cells may control rotavirus infection and probably contribute to the prevention of its dissemination.
publisher Associação Brasileira de Divulgação Científica
publishDate 1997
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997001000008
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AT nozawacm rotavirusandreovirusinteractionwithmouseperitonealresidentphagocyticcells
AT guimaraesacc rotavirusandreovirusinteractionwithmouseperitonealresidentphagocyticcells
AT ramoss rotavirusandreovirusinteractionwithmouseperitonealresidentphagocyticcells
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