Evaluation of a recombinant p24 antigen for the detection of Feline Immunodeficiency Virus-specific antibodies
Feline Immunodeficiency Virus is a worldwide infection and is considered a significant pathogen. The diagnosis of FIV infections is mainly based on commercially available rapid tests that are highly expensive in Brazil, hence it is rarely performed in the country. Furthermore, lentiviruses grow slowly and poorly in tissue cultures, making the production of viral antigen by classic means and thus the establishment of FIV immunodiagnosis impracticable. In order to deal with this, recombinant DNA techniques were adopted to produce the protein p24, a viral capsid antigen. The protein's reactivity evaluation analyzed by Western blot indicated that this recombinant antigen can be a useful tool for the immunodiagnostic of FIV infections.
Saved in:
Main Authors: | Mazur,Carlos, Reis,Jenner K.P, Leite,Romulo C, Danelli,Maria das Graças M, Hagiwara,Mitika K, Góes,Ana Carolina M.A. de, Medeiros,Marcos A |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Colégio Brasileiro de Patologia Animal - CBPA
2010
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2010001000011 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Serodiagnosis of tuberculosis: specific detection of free and complex-dissociated antibodies anti-mycobacterium tuberculosis recombinant antigens
by: Imaz,María Susana, et al.
Published: (2008) -
Association of the feline gingivostomatitis complex with the feline immunodeficiency virus and the feline leukemia virus
by: Gonzalez, Roger
Published: (2022) -
Identification of Theileria mutans-specific antigen for use in antibody and antigen detection ELISA
by: Katende, J.M., et al.
Published: (2013-06-11T09:23:22Z) -
Detecting regressive feline leukemia infections and feline immunodeficiency coinfections in cats with clinical signs and hematological alterations related to retroviral infection
by: Canto-Valdés,María Casandra, et al.
Published: (2022) -
Occurrence of feline immunodeficiency virus infection in cats
by: Lara,Valéria Maria, et al.
Published: (2008)