Value of the Ultrasound in the Study of Ovarian Reserve for Prediction of Oocyte Recovery

Value of the Ultrasound in the Study of Ovarian Reserve for Prediction of Oocyte Recovery

Abstract Purpose To identify which methods used in the assessment of the ovarian reserve are exclusive or complementary to identify the best response to follicle development. Methods Retrospective cohort study, involving patients undergoing assisted reproduction treatment at the Instituto de Medicina Reprodutiva e Fetal, from April 2009 to July 2014. Age, biochemical tests, and ultrasound were assessed. The data were analyzed to predict the follicular development and the relation between them, using, for statistical analysis, Statistical Package for Social Sciences software. Results Out of the 293 couples included, 50.2% presented infertility by ovarian factor. Considering the age as the main variable, a significant negative correlation with the volume of both ovaries was observed (right ovary, r = 0.21; left ovary, r =0.22; both p< 0.0001), and with the antral follicle count (right ovary, r =0.38; left ovary, r =0.47; both p< 0.0001). Considering the antral follicle count as the main variable, a significant positive correlation with the total recruited oocytes was observed. When we correlated the antral follicle count with the recruited follicles larger than 18 mm, we observed that, with a cutoff of 12 antral follicles, there is a positive predictive value of 99%, and an area under the ROC curve of 0.76. Conclusion We concluded from our study that age and antral follicle count are effective predictors of ovarian response in cycles of assisted reproduction. The ovarian volume, as well as the anti-Müllerian hormone dosage, seem to be adequate markers of the ovarian reserve.

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Main Authors: Spressão,Meire, Oliani,Antonio Hélio, Oliani,Denise Cristina Mós Vaz
Format: Digital revista
Language:English
Published: Federação Brasileira das Sociedades de Ginecologia e Obstetrícia 2016
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032016001000499
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spelling oai:scielo:S0100-720320160010004992017-01-13Value of the Ultrasound in the Study of Ovarian Reserve for Prediction of Oocyte RecoverySpressão,MeireOliani,Antonio HélioOliani,Denise Cristina Mós Vaz in vitro fertilization ultrasound ovarian function tests ovarian reserve Abstract Purpose To identify which methods used in the assessment of the ovarian reserve are exclusive or complementary to identify the best response to follicle development. Methods Retrospective cohort study, involving patients undergoing assisted reproduction treatment at the Instituto de Medicina Reprodutiva e Fetal, from April 2009 to July 2014. Age, biochemical tests, and ultrasound were assessed. The data were analyzed to predict the follicular development and the relation between them, using, for statistical analysis, Statistical Package for Social Sciences software. Results Out of the 293 couples included, 50.2% presented infertility by ovarian factor. Considering the age as the main variable, a significant negative correlation with the volume of both ovaries was observed (right ovary, r = 0.21; left ovary, r =0.22; both p< 0.0001), and with the antral follicle count (right ovary, r =0.38; left ovary, r =0.47; both p< 0.0001). Considering the antral follicle count as the main variable, a significant positive correlation with the total recruited oocytes was observed. When we correlated the antral follicle count with the recruited follicles larger than 18 mm, we observed that, with a cutoff of 12 antral follicles, there is a positive predictive value of 99%, and an area under the ROC curve of 0.76. Conclusion We concluded from our study that age and antral follicle count are effective predictors of ovarian response in cycles of assisted reproduction. The ovarian volume, as well as the anti-Müllerian hormone dosage, seem to be adequate markers of the ovarian reserve.info:eu-repo/semantics/openAccessFederação Brasileira das Sociedades de Ginecologia e ObstetríciaRevista Brasileira de Ginecologia e Obstetrícia v.38 n.10 20162016-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032016001000499en10.1055/s-0036-1593969
institution SCIELO
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countrycode BR
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access En linea
databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Spressão,Meire
Oliani,Antonio Hélio
Oliani,Denise Cristina Mós Vaz
spellingShingle Spressão,Meire
Oliani,Antonio Hélio
Oliani,Denise Cristina Mós Vaz
Value of the Ultrasound in the Study of Ovarian Reserve for Prediction of Oocyte Recovery
author_facet Spressão,Meire
Oliani,Antonio Hélio
Oliani,Denise Cristina Mós Vaz
author_sort Spressão,Meire
title Value of the Ultrasound in the Study of Ovarian Reserve for Prediction of Oocyte Recovery
title_short Value of the Ultrasound in the Study of Ovarian Reserve for Prediction of Oocyte Recovery
title_full Value of the Ultrasound in the Study of Ovarian Reserve for Prediction of Oocyte Recovery
title_fullStr Value of the Ultrasound in the Study of Ovarian Reserve for Prediction of Oocyte Recovery
title_full_unstemmed Value of the Ultrasound in the Study of Ovarian Reserve for Prediction of Oocyte Recovery
title_sort value of the ultrasound in the study of ovarian reserve for prediction of oocyte recovery
description Abstract Purpose To identify which methods used in the assessment of the ovarian reserve are exclusive or complementary to identify the best response to follicle development. Methods Retrospective cohort study, involving patients undergoing assisted reproduction treatment at the Instituto de Medicina Reprodutiva e Fetal, from April 2009 to July 2014. Age, biochemical tests, and ultrasound were assessed. The data were analyzed to predict the follicular development and the relation between them, using, for statistical analysis, Statistical Package for Social Sciences software. Results Out of the 293 couples included, 50.2% presented infertility by ovarian factor. Considering the age as the main variable, a significant negative correlation with the volume of both ovaries was observed (right ovary, r = 0.21; left ovary, r =0.22; both p< 0.0001), and with the antral follicle count (right ovary, r =0.38; left ovary, r =0.47; both p< 0.0001). Considering the antral follicle count as the main variable, a significant positive correlation with the total recruited oocytes was observed. When we correlated the antral follicle count with the recruited follicles larger than 18 mm, we observed that, with a cutoff of 12 antral follicles, there is a positive predictive value of 99%, and an area under the ROC curve of 0.76. Conclusion We concluded from our study that age and antral follicle count are effective predictors of ovarian response in cycles of assisted reproduction. The ovarian volume, as well as the anti-Müllerian hormone dosage, seem to be adequate markers of the ovarian reserve.
publisher Federação Brasileira das Sociedades de Ginecologia e Obstetrícia
publishDate 2016
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032016001000499
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AT olianidenisecristinamosvaz valueoftheultrasoundinthestudyofovarianreserveforpredictionofoocyterecovery
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