Nuss procedure for Pectus excavatum repair: critical appraisal of the evidence

Objective: To evaluate the effectiveness and safety of correction of pectus excavatum by the Nuss technique based on the available scientific evidence.Methods: We conducted an evidence synthesis following systematic processes of search, selection, extraction and critical appraisal. Outcomes were classified by importance and had their quality assessed by the Grading of Recommendations Assessment, Development and Evaluation (GRADE).Results: The process of selection of items led to the inclusion of only one systematic review, which synthesized the results of nine observational studies comparing the Nuss and Ravitch procedures. The evidence found was rated as poor and very poor quality. The Nuss procedure has increased the incidence of hemothorax (RR = 5.15; 95% CI: 1.07; 24.89), pneumothorax (RR = 5.26; 95% CI: 1.55; 17.92) and the need for reintervention (RR = 4.88; 95% CI: 2.41; 9.88) when compared to the Ravitch. There was no statistical difference between the two procedures in outcomes: general complications, blood transfusion, hospital stay and time to ambulation. The Nuss operation was faster than the Ravitch (mean difference [MD] = -69.94 minutes, 95% CI: -139.04, -0.83).Conclusion: In the absence of well-designed prospective studies to clarify the evidence, especially in terms of aesthetics and quality of life, surgical indication should be individualized and the choice of the technique based on patient preference and experience of the team.

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Main Authors: Araújo,Maria Elizete de Almeida, Penha,Anderson da Paz, Westphal,Fernando Luiz, Silva,Marcus Tolentino, Galvão,Taís Freire
Format: Digital revista
Language:English
Published: Colégio Brasileiro de Cirurgiões 2014
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912014000600400
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spelling oai:scielo:S0100-699120140006004002015-09-25Nuss procedure for Pectus excavatum repair: critical appraisal of the evidenceAraújo,Maria Elizete de AlmeidaPenha,Anderson da PazWestphal,Fernando LuizSilva,Marcus TolentinoGalvão,Taís Freire Funnel chest Evidence-based medicine Effectiveness Surgical procedures, operative Objective: To evaluate the effectiveness and safety of correction of pectus excavatum by the Nuss technique based on the available scientific evidence.Methods: We conducted an evidence synthesis following systematic processes of search, selection, extraction and critical appraisal. Outcomes were classified by importance and had their quality assessed by the Grading of Recommendations Assessment, Development and Evaluation (GRADE).Results: The process of selection of items led to the inclusion of only one systematic review, which synthesized the results of nine observational studies comparing the Nuss and Ravitch procedures. The evidence found was rated as poor and very poor quality. The Nuss procedure has increased the incidence of hemothorax (RR = 5.15; 95% CI: 1.07; 24.89), pneumothorax (RR = 5.26; 95% CI: 1.55; 17.92) and the need for reintervention (RR = 4.88; 95% CI: 2.41; 9.88) when compared to the Ravitch. There was no statistical difference between the two procedures in outcomes: general complications, blood transfusion, hospital stay and time to ambulation. The Nuss operation was faster than the Ravitch (mean difference [MD] = -69.94 minutes, 95% CI: -139.04, -0.83).Conclusion: In the absence of well-designed prospective studies to clarify the evidence, especially in terms of aesthetics and quality of life, surgical indication should be individualized and the choice of the technique based on patient preference and experience of the team.info:eu-repo/semantics/openAccessColégio Brasileiro de CirurgiõesRevista do Colégio Brasileiro de Cirurgiões v.41 n.6 20142014-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912014000600400en10.1590/0100-69912014006004
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countrycode BR
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libraryname SciELO
language English
format Digital
author Araújo,Maria Elizete de Almeida
Penha,Anderson da Paz
Westphal,Fernando Luiz
Silva,Marcus Tolentino
Galvão,Taís Freire
spellingShingle Araújo,Maria Elizete de Almeida
Penha,Anderson da Paz
Westphal,Fernando Luiz
Silva,Marcus Tolentino
Galvão,Taís Freire
Nuss procedure for Pectus excavatum repair: critical appraisal of the evidence
author_facet Araújo,Maria Elizete de Almeida
Penha,Anderson da Paz
Westphal,Fernando Luiz
Silva,Marcus Tolentino
Galvão,Taís Freire
author_sort Araújo,Maria Elizete de Almeida
title Nuss procedure for Pectus excavatum repair: critical appraisal of the evidence
title_short Nuss procedure for Pectus excavatum repair: critical appraisal of the evidence
title_full Nuss procedure for Pectus excavatum repair: critical appraisal of the evidence
title_fullStr Nuss procedure for Pectus excavatum repair: critical appraisal of the evidence
title_full_unstemmed Nuss procedure for Pectus excavatum repair: critical appraisal of the evidence
title_sort nuss procedure for pectus excavatum repair: critical appraisal of the evidence
description Objective: To evaluate the effectiveness and safety of correction of pectus excavatum by the Nuss technique based on the available scientific evidence.Methods: We conducted an evidence synthesis following systematic processes of search, selection, extraction and critical appraisal. Outcomes were classified by importance and had their quality assessed by the Grading of Recommendations Assessment, Development and Evaluation (GRADE).Results: The process of selection of items led to the inclusion of only one systematic review, which synthesized the results of nine observational studies comparing the Nuss and Ravitch procedures. The evidence found was rated as poor and very poor quality. The Nuss procedure has increased the incidence of hemothorax (RR = 5.15; 95% CI: 1.07; 24.89), pneumothorax (RR = 5.26; 95% CI: 1.55; 17.92) and the need for reintervention (RR = 4.88; 95% CI: 2.41; 9.88) when compared to the Ravitch. There was no statistical difference between the two procedures in outcomes: general complications, blood transfusion, hospital stay and time to ambulation. The Nuss operation was faster than the Ravitch (mean difference [MD] = -69.94 minutes, 95% CI: -139.04, -0.83).Conclusion: In the absence of well-designed prospective studies to clarify the evidence, especially in terms of aesthetics and quality of life, surgical indication should be individualized and the choice of the technique based on patient preference and experience of the team.
publisher Colégio Brasileiro de Cirurgiões
publishDate 2014
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912014000600400
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