Lymph node metastasis in early gastric cancer

OBJECTIVE: to evaluate the incidence of lymph node metastasis in early gastric cancer, identifying risk factors for its development. METHODS: we conducted a prospective study of patients with gastric cancer admitted to the Section of the Esophago-Gastric Surgery of the Surgery of Service HUCFF-UFRJ, from January 2006 to May 2012. RESULTS: the rate of early gastric cancer was 16.3%. The incidence of nodal metastases was 30.8% and occurred more frequently in patients with tumors with involvement of the submucosa (42.9%), in those poorly differentiated (36.4%), in tumors larger than 2 cm (33.3%) and in type III ulcerated lesions (43.8%). CONCLUSION: the incidence of lymph node metastases in patients was very high and suggests that one should keep the radicality of resection in early gastric cancer, particularly in relation to D2 lymphadenectomy, recommended for advanced gastric cancer. Conservative resections, with lymphadenectomies smaller than D2, should be performed only in selected cases, well-studied as for the risk factors of lymph node metastasis. Despite the small number of cases did not permit to relate the rate of lymph node metastasis to the risk factors considered, we noted a strong tendency for the occurrence of these metastases in the poorly differentiated, type III, larger than 2 cm tumors, and in the Lauren diffuse types.

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Main Authors: Bravo Neto,Guilherme Pinto, Santos,Elizabeth Gomes Dos, Victer,Felipe Carvalho, Carvalho,Carlos Eduardo De Souza
Format: Digital revista
Language:English
Published: Colégio Brasileiro de Cirurgiões 2014
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912014000100011
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spelling oai:scielo:S0100-699120140001000112014-04-22Lymph node metastasis in early gastric cancerBravo Neto,Guilherme PintoSantos,Elizabeth Gomes DosVicter,Felipe CarvalhoCarvalho,Carlos Eduardo De Souza Stomach neoplasms Lymphatic metastasis Gastrectomy Lymph node excision Risk factors OBJECTIVE: to evaluate the incidence of lymph node metastasis in early gastric cancer, identifying risk factors for its development. METHODS: we conducted a prospective study of patients with gastric cancer admitted to the Section of the Esophago-Gastric Surgery of the Surgery of Service HUCFF-UFRJ, from January 2006 to May 2012. RESULTS: the rate of early gastric cancer was 16.3%. The incidence of nodal metastases was 30.8% and occurred more frequently in patients with tumors with involvement of the submucosa (42.9%), in those poorly differentiated (36.4%), in tumors larger than 2 cm (33.3%) and in type III ulcerated lesions (43.8%). CONCLUSION: the incidence of lymph node metastases in patients was very high and suggests that one should keep the radicality of resection in early gastric cancer, particularly in relation to D2 lymphadenectomy, recommended for advanced gastric cancer. Conservative resections, with lymphadenectomies smaller than D2, should be performed only in selected cases, well-studied as for the risk factors of lymph node metastasis. Despite the small number of cases did not permit to relate the rate of lymph node metastasis to the risk factors considered, we noted a strong tendency for the occurrence of these metastases in the poorly differentiated, type III, larger than 2 cm tumors, and in the Lauren diffuse types. info:eu-repo/semantics/openAccessColégio Brasileiro de CirurgiõesRevista do Colégio Brasileiro de Cirurgiões v.41 n.1 20142014-02-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912014000100011en10.1590/S0100-69912014000100004
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country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Bravo Neto,Guilherme Pinto
Santos,Elizabeth Gomes Dos
Victer,Felipe Carvalho
Carvalho,Carlos Eduardo De Souza
spellingShingle Bravo Neto,Guilherme Pinto
Santos,Elizabeth Gomes Dos
Victer,Felipe Carvalho
Carvalho,Carlos Eduardo De Souza
Lymph node metastasis in early gastric cancer
author_facet Bravo Neto,Guilherme Pinto
Santos,Elizabeth Gomes Dos
Victer,Felipe Carvalho
Carvalho,Carlos Eduardo De Souza
author_sort Bravo Neto,Guilherme Pinto
title Lymph node metastasis in early gastric cancer
title_short Lymph node metastasis in early gastric cancer
title_full Lymph node metastasis in early gastric cancer
title_fullStr Lymph node metastasis in early gastric cancer
title_full_unstemmed Lymph node metastasis in early gastric cancer
title_sort lymph node metastasis in early gastric cancer
description OBJECTIVE: to evaluate the incidence of lymph node metastasis in early gastric cancer, identifying risk factors for its development. METHODS: we conducted a prospective study of patients with gastric cancer admitted to the Section of the Esophago-Gastric Surgery of the Surgery of Service HUCFF-UFRJ, from January 2006 to May 2012. RESULTS: the rate of early gastric cancer was 16.3%. The incidence of nodal metastases was 30.8% and occurred more frequently in patients with tumors with involvement of the submucosa (42.9%), in those poorly differentiated (36.4%), in tumors larger than 2 cm (33.3%) and in type III ulcerated lesions (43.8%). CONCLUSION: the incidence of lymph node metastases in patients was very high and suggests that one should keep the radicality of resection in early gastric cancer, particularly in relation to D2 lymphadenectomy, recommended for advanced gastric cancer. Conservative resections, with lymphadenectomies smaller than D2, should be performed only in selected cases, well-studied as for the risk factors of lymph node metastasis. Despite the small number of cases did not permit to relate the rate of lymph node metastasis to the risk factors considered, we noted a strong tendency for the occurrence of these metastases in the poorly differentiated, type III, larger than 2 cm tumors, and in the Lauren diffuse types.
publisher Colégio Brasileiro de Cirurgiões
publishDate 2014
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912014000100011
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AT santoselizabethgomesdos lymphnodemetastasisinearlygastriccancer
AT victerfelipecarvalho lymphnodemetastasisinearlygastriccancer
AT carvalhocarloseduardodesouza lymphnodemetastasisinearlygastriccancer
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