Phytochemical profile, toxicity and antioxidant activity of Aloysia gratissima (Verbenaceae)

Aloysia gratissima (Gill. et Hook) Tronc. (Verbenaceae) is native to South America with folk therapeutic applications for a wide range of diseases. The polyphenolic and carotenoid profile, toxicity, and antioxidant activity of aqueous extract of Aloysia gratissima were investigated. HPLC analyses showed high amounts of ferulic acid, trans-cinnamic acid and p-coumaric acid, and also trans-β- carotene and lutein which fluctuated throughout the seasons. Furthermore, the extract investigated not only exerted antioxidant activity but also inhibited lipid peroxidation. Toxicity was achieved only at the highest dose tested. Therefore, A. gratissima is a potential species for medicinal purposes.

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Main Authors: Zeni,Ana Lúcia B., Albuquerque,Cláudia Almeida C. de, Gonçalves,Filipe, Latini,Alexandra, Tasca,Carla I., Podestá,Rossana, Pagliosa,Cristiane M., Duarte,Filipe S., Lima,Thereza C. M. de, Maraschin,Marcelo
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Química 2013
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422013000100013
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spelling oai:scielo:S0100-404220130001000132013-02-15Phytochemical profile, toxicity and antioxidant activity of Aloysia gratissima (Verbenaceae)Zeni,Ana Lúcia B.Albuquerque,Cláudia Almeida C. deGonçalves,FilipeLatini,AlexandraTasca,Carla I.Podestá,RossanaPagliosa,Cristiane M.Duarte,Filipe S.Lima,Thereza C. M. deMaraschin,Marcelo Aloysia gratissima Verbenaceae antioxidant activity Aloysia gratissima (Gill. et Hook) Tronc. (Verbenaceae) is native to South America with folk therapeutic applications for a wide range of diseases. The polyphenolic and carotenoid profile, toxicity, and antioxidant activity of aqueous extract of Aloysia gratissima were investigated. HPLC analyses showed high amounts of ferulic acid, trans-cinnamic acid and p-coumaric acid, and also trans-β- carotene and lutein which fluctuated throughout the seasons. Furthermore, the extract investigated not only exerted antioxidant activity but also inhibited lipid peroxidation. Toxicity was achieved only at the highest dose tested. Therefore, A. gratissima is a potential species for medicinal purposes.info:eu-repo/semantics/openAccessSociedade Brasileira de QuímicaQuímica Nova v.36 n.1 20132013-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422013000100013en10.1590/S0100-40422013000100013
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region America del Sur
libraryname SciELO
language English
format Digital
author Zeni,Ana Lúcia B.
Albuquerque,Cláudia Almeida C. de
Gonçalves,Filipe
Latini,Alexandra
Tasca,Carla I.
Podestá,Rossana
Pagliosa,Cristiane M.
Duarte,Filipe S.
Lima,Thereza C. M. de
Maraschin,Marcelo
spellingShingle Zeni,Ana Lúcia B.
Albuquerque,Cláudia Almeida C. de
Gonçalves,Filipe
Latini,Alexandra
Tasca,Carla I.
Podestá,Rossana
Pagliosa,Cristiane M.
Duarte,Filipe S.
Lima,Thereza C. M. de
Maraschin,Marcelo
Phytochemical profile, toxicity and antioxidant activity of Aloysia gratissima (Verbenaceae)
author_facet Zeni,Ana Lúcia B.
Albuquerque,Cláudia Almeida C. de
Gonçalves,Filipe
Latini,Alexandra
Tasca,Carla I.
Podestá,Rossana
Pagliosa,Cristiane M.
Duarte,Filipe S.
Lima,Thereza C. M. de
Maraschin,Marcelo
author_sort Zeni,Ana Lúcia B.
title Phytochemical profile, toxicity and antioxidant activity of Aloysia gratissima (Verbenaceae)
title_short Phytochemical profile, toxicity and antioxidant activity of Aloysia gratissima (Verbenaceae)
title_full Phytochemical profile, toxicity and antioxidant activity of Aloysia gratissima (Verbenaceae)
title_fullStr Phytochemical profile, toxicity and antioxidant activity of Aloysia gratissima (Verbenaceae)
title_full_unstemmed Phytochemical profile, toxicity and antioxidant activity of Aloysia gratissima (Verbenaceae)
title_sort phytochemical profile, toxicity and antioxidant activity of aloysia gratissima (verbenaceae)
description Aloysia gratissima (Gill. et Hook) Tronc. (Verbenaceae) is native to South America with folk therapeutic applications for a wide range of diseases. The polyphenolic and carotenoid profile, toxicity, and antioxidant activity of aqueous extract of Aloysia gratissima were investigated. HPLC analyses showed high amounts of ferulic acid, trans-cinnamic acid and p-coumaric acid, and also trans-β- carotene and lutein which fluctuated throughout the seasons. Furthermore, the extract investigated not only exerted antioxidant activity but also inhibited lipid peroxidation. Toxicity was achieved only at the highest dose tested. Therefore, A. gratissima is a potential species for medicinal purposes.
publisher Sociedade Brasileira de Química
publishDate 2013
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422013000100013
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