Ultrasound evaluation of schistosomiasis-related morbidity among the Xakriabá people in the state of Minas Gerais, Brazil
Abstract Objective: To use ultrasound to investigate the morbidity related to schistosomiasis in the Xakriabá indigenous population. Materials and Methods: This was a field-based census study conducted in the territory of the Xakriabá people. A total of 166 individuals were invited, and 148 (≤ 77 years of age) agreed to participate. Most participants underwent abdominal ultrasound, physical examination, and stool examination. Mann-Whitney U and chi-square tests were used for comparisons. We determined risk by calculating odds ratio (OR) and performed logistic regression analysis. Results: Schistosoma mansoni eggs were found in 31 (26.7%) of the 116 stool samples examined, 22 (70.9%) of the 31 being from individuals 4-16 years of age. The median count was 144 eggs/g of feces (interquartile range, 264). Of the 105 participants examined with ultrasound, 68 (64.8%) had hepatomegaly (left lobe), 6 (5.7%) had splenomegaly, and 4 (3.8%) had portal hypertension. Egg-positive stool samples were more common in those with an enlarged left lobe (OR = 3.4; 95% confidence interval (CI): 1.1-11.2; p = 0.043). Periportal fibrosis was found in 30 participants (28.6%), of whom 9 (30%) had pattern C, 10 (33.3%) had pattern D, and 11 (36.7%) had pattern Dc. Age was the only independent risk factor for fibrosis (p = 0.007). Fibrosis was up to nine-fold more common in alcohol drinkers than in nondrinkers (OR = 9.28; 95% CI: 2.60-33.06; p < 0.001). Among the 138 participants in whom the clinical form was classified, the chronic hepatic form was identified in 54 (39.1%), of whom 32 (59.2%) were under 30 years of age and one (1.8%) was hepatosplenic. Conclusion: Schistosomiasis in the Xakriabá population is characterized by a high frequency of egg-positive stool samples, predominantly in children/adolescents, and by chronic hepatic form in the young, especially among alcohol drinkers.
Main Authors: | Marinho,Carolina Coimbra, Nicolato,Aline Joice Pereira Gonçalves, Reis,Vivian Walter, Santos,Rosiane Cristina dos, Silva,Jaime Costa, Faria,Henrique Pereira, Machado-Coelho,George Luiz Lins |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem
2020
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842020000100004 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Morbidity of schistosomiasis mansoni in a low endemic setting in Ouro Preto, Minas Gerais, Brazil
by: Marinho,Carolina Coimbra, et al.
Published: (2017) -
Morbidity of schistosomiasis mansoni in the state of Minas Gerais, Brazil
by: Drummond,Sandra Costa, et al.
Published: (2006) -
Influence of specific treatment on the morbidity of schistosomiasis mansoni in an endemic area of Minas Gerais, Brazil
by: Conceição,Maria José, et al.
Published: (2002) -
Ecology of phlebotomine sand flies in an area of leishmaniasis occurrence in the Xakriabá Indigenous Reserve, Minas Gerais, Brazil
by: Costa,André Tetzl, et al.
Published: (2019) -
Tempo de aleitamento materno entre indígenas Xakriabá aldeados em Minas Gerais, Sudeste do Brasil
by: Sírio,Marília Alfenas de Oliveira, et al.
Published: (2015)