Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients
Immunocompromised patients may develop severe chronic anaemia when infected by human parvovirus B19 (B19V). However, this is not the case in human immunodeficiency virus (HIV)-infected patients with good adherence to highly active antiretroviral treatment (HAART). In this study, we investigated the clinical evolution of five HIV-infected patients receiving HAART who had B19V infections confirmed by serum polymerase chain reaction. Four of the patients were infected with genotype 1a strains and the remaining patient was infected with a genotype 3b strain. Anaemia was detected in three of the patients, but all patients recovered without requiring immunoglobulin and/or blood transfusions. In all cases, the attending physicians did not suspect the B19V infections. There was no apparent relationship between the infecting genotype and the clinical course. In the HAART era, B19V infections in HIV-positive patients may be limited, subtle or unapparent.
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Instituto Oswaldo Cruz, Ministério da Saúde
2014
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oai:scielo:S0074-027620140002001682015-02-24Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patientsPereira,Renata Freire AlvesGarcia,Rita de Cássia Nasser CubelAzevedo,Kátia Martins Lopes deSetúbal,SérgioSiqueira,Marilda Agudo Mendonça Teixeira deOliveira,Solange Artimos de HIV human parvovirus B19 seroconversion Immunocompromised patients may develop severe chronic anaemia when infected by human parvovirus B19 (B19V). However, this is not the case in human immunodeficiency virus (HIV)-infected patients with good adherence to highly active antiretroviral treatment (HAART). In this study, we investigated the clinical evolution of five HIV-infected patients receiving HAART who had B19V infections confirmed by serum polymerase chain reaction. Four of the patients were infected with genotype 1a strains and the remaining patient was infected with a genotype 3b strain. Anaemia was detected in three of the patients, but all patients recovered without requiring immunoglobulin and/or blood transfusions. In all cases, the attending physicians did not suspect the B19V infections. There was no apparent relationship between the infecting genotype and the clinical course. In the HAART era, B19V infections in HIV-positive patients may be limited, subtle or unapparent.info:eu-repo/semantics/openAccessInstituto Oswaldo Cruz, Ministério da SaúdeMemórias do Instituto Oswaldo Cruz v.109 n.2 20142014-04-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000200168en10.1590/0074-02760130312 |
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Pereira,Renata Freire Alves Garcia,Rita de Cássia Nasser Cubel Azevedo,Kátia Martins Lopes de Setúbal,Sérgio Siqueira,Marilda Agudo Mendonça Teixeira de Oliveira,Solange Artimos de |
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Pereira,Renata Freire Alves Garcia,Rita de Cássia Nasser Cubel Azevedo,Kátia Martins Lopes de Setúbal,Sérgio Siqueira,Marilda Agudo Mendonça Teixeira de Oliveira,Solange Artimos de Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients |
author_facet |
Pereira,Renata Freire Alves Garcia,Rita de Cássia Nasser Cubel Azevedo,Kátia Martins Lopes de Setúbal,Sérgio Siqueira,Marilda Agudo Mendonça Teixeira de Oliveira,Solange Artimos de |
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Pereira,Renata Freire Alves |
title |
Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients |
title_short |
Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients |
title_full |
Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients |
title_fullStr |
Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients |
title_full_unstemmed |
Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients |
title_sort |
clinical features and laboratory findings of human parvovirus b19 in human immunodeficiency virus-infected patients |
description |
Immunocompromised patients may develop severe chronic anaemia when infected by human parvovirus B19 (B19V). However, this is not the case in human immunodeficiency virus (HIV)-infected patients with good adherence to highly active antiretroviral treatment (HAART). In this study, we investigated the clinical evolution of five HIV-infected patients receiving HAART who had B19V infections confirmed by serum polymerase chain reaction. Four of the patients were infected with genotype 1a strains and the remaining patient was infected with a genotype 3b strain. Anaemia was detected in three of the patients, but all patients recovered without requiring immunoglobulin and/or blood transfusions. In all cases, the attending physicians did not suspect the B19V infections. There was no apparent relationship between the infecting genotype and the clinical course. In the HAART era, B19V infections in HIV-positive patients may be limited, subtle or unapparent. |
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Instituto Oswaldo Cruz, Ministério da Saúde |
publishDate |
2014 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000200168 |
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