The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata
Since the internal defense system of mollusks consists of cellular and humoral mechanisms, we examined the role of hydrocortisone in mollusks defense cells and the influence of this steroid on the development of Schistosoma mansoni in its intermediary host. Hydrocortisone had an immunosuppressive action in Biomphalaria glabrata, as reflected in the reduced number of defense cells and the altered cell physiology. Histopathological analysis showed that hydrocortisone facilitated the intramolluscan development of S. mansoni, by reducing the extent of the inflammatory response, seen as a greater number of viable sporocysts with no surrounding hemocytes.
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Instituto Oswaldo Cruz, Ministério da Saúde
2002
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oai:scielo:S0074-027620020006000242002-10-15The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrataSerrano,Deborah ReginaZanotti-Magalhães,Eliana MariaMagalhães,Luiz AugustoCarvalho,José Ferreira de Schistosoma mansoni Biomphalaria glabrata hydrocortisone sporocyst hemocyte reaction Since the internal defense system of mollusks consists of cellular and humoral mechanisms, we examined the role of hydrocortisone in mollusks defense cells and the influence of this steroid on the development of Schistosoma mansoni in its intermediary host. Hydrocortisone had an immunosuppressive action in Biomphalaria glabrata, as reflected in the reduced number of defense cells and the altered cell physiology. Histopathological analysis showed that hydrocortisone facilitated the intramolluscan development of S. mansoni, by reducing the extent of the inflammatory response, seen as a greater number of viable sporocysts with no surrounding hemocytes.info:eu-repo/semantics/openAccessInstituto Oswaldo Cruz, Ministério da SaúdeMemórias do Instituto Oswaldo Cruz v.97 n.6 20022002-09-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600024en10.1590/S0074-02762002000600024 |
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Serrano,Deborah Regina Zanotti-Magalhães,Eliana Maria Magalhães,Luiz Augusto Carvalho,José Ferreira de |
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Serrano,Deborah Regina Zanotti-Magalhães,Eliana Maria Magalhães,Luiz Augusto Carvalho,José Ferreira de The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata |
| author_facet |
Serrano,Deborah Regina Zanotti-Magalhães,Eliana Maria Magalhães,Luiz Augusto Carvalho,José Ferreira de |
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Serrano,Deborah Regina |
| title |
The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata |
| title_short |
The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata |
| title_full |
The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata |
| title_fullStr |
The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata |
| title_full_unstemmed |
The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata |
| title_sort |
influence of hydrocortisone on cellular defence mechanisms of biomphalaria glabrata |
| description |
Since the internal defense system of mollusks consists of cellular and humoral mechanisms, we examined the role of hydrocortisone in mollusks defense cells and the influence of this steroid on the development of Schistosoma mansoni in its intermediary host. Hydrocortisone had an immunosuppressive action in Biomphalaria glabrata, as reflected in the reduced number of defense cells and the altered cell physiology. Histopathological analysis showed that hydrocortisone facilitated the intramolluscan development of S. mansoni, by reducing the extent of the inflammatory response, seen as a greater number of viable sporocysts with no surrounding hemocytes. |
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Instituto Oswaldo Cruz, Ministério da Saúde |
| publishDate |
2002 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600024 |
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