Bundle branch and atrioventricular block as complications of acute myocardial infarction in the thrombolytic era

OBJECTIVE: To analyze the incidence of intraventricular and atrioventricular conduction defects associated with acute myocardial infarction and the degree of in hospital mortality resulting from this condition during the era of thrombolytic therapy. METHODS: Observational study of a cohort of 929 consecutive patients with acute myocardial infarction. Multivariate analysis by logistic regression. Was used. RESULTS: Logistic regression showed a greater incidence of bundle branch block in male sex (odds ratio = 1.87, 95% CI = 1.02-3.42), age over 70 years (odds ratio = 2.31, 95% CI = 1.68-5.00), anterior localization of the infarction (odds ratio = 1.93, 95% CI = 1.03-3.65). There was a greater incidence of complete atrioventricular block in inferior infarcts (odds ratio = 2.59, 95% CI 1.30-5.18) and the presence of cardiogenic shock (odds ratio = 3.90, 95% CI = 1.43-10.65). Use of a thrombolytic agent was associated with a tendency toward a lower occurrence of bundle branch block (odds ratio = 0.68) and a greater occurrence of complete atrioventricular block (odds ratio = 1.44). The presence of bundle branch block (odds ratio = 2.45 95% , CI = 1.14-5.28) and of complete atrioventricular block (odds ratio = 13.59, 95% CI = 5.43-33.98) was associated with a high and independent probability of inhospital death. CONCLUSION: During the current era of thrombolytic therapy and in this population, intraventricular disturbances of electrical conduction and complete atrioventricular block were associated with a high and independent risk of inhospital death during acute myocardial infarction.

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Main Authors: Escosteguy,Claudia Caminha, Carvalho,Marciano de Almeida, Medronho,Roberto de Andrade, Abreu,Luiz Maurino, Monteiro Filho,Mario Ypiranga
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Cardiologia - SBC 2001
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2001000400003
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spelling oai:scielo:S0066-782X20010004000032002-01-08Bundle branch and atrioventricular block as complications of acute myocardial infarction in the thrombolytic eraEscosteguy,Claudia CaminhaCarvalho,Marciano de AlmeidaMedronho,Roberto de AndradeAbreu,Luiz MaurinoMonteiro Filho,Mario Ypiranga Bundle branch block complete atrioventricular block thrombolysis OBJECTIVE: To analyze the incidence of intraventricular and atrioventricular conduction defects associated with acute myocardial infarction and the degree of in hospital mortality resulting from this condition during the era of thrombolytic therapy. METHODS: Observational study of a cohort of 929 consecutive patients with acute myocardial infarction. Multivariate analysis by logistic regression. Was used. RESULTS: Logistic regression showed a greater incidence of bundle branch block in male sex (odds ratio = 1.87, 95% CI = 1.02-3.42), age over 70 years (odds ratio = 2.31, 95% CI = 1.68-5.00), anterior localization of the infarction (odds ratio = 1.93, 95% CI = 1.03-3.65). There was a greater incidence of complete atrioventricular block in inferior infarcts (odds ratio = 2.59, 95% CI 1.30-5.18) and the presence of cardiogenic shock (odds ratio = 3.90, 95% CI = 1.43-10.65). Use of a thrombolytic agent was associated with a tendency toward a lower occurrence of bundle branch block (odds ratio = 0.68) and a greater occurrence of complete atrioventricular block (odds ratio = 1.44). The presence of bundle branch block (odds ratio = 2.45 95% , CI = 1.14-5.28) and of complete atrioventricular block (odds ratio = 13.59, 95% CI = 5.43-33.98) was associated with a high and independent probability of inhospital death. CONCLUSION: During the current era of thrombolytic therapy and in this population, intraventricular disturbances of electrical conduction and complete atrioventricular block were associated with a high and independent risk of inhospital death during acute myocardial infarction.info:eu-repo/semantics/openAccessSociedade Brasileira de Cardiologia - SBCArquivos Brasileiros de Cardiologia v.76 n.4 20012001-04-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2001000400003en10.1590/S0066-782X2001000400003
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language English
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author Escosteguy,Claudia Caminha
Carvalho,Marciano de Almeida
Medronho,Roberto de Andrade
Abreu,Luiz Maurino
Monteiro Filho,Mario Ypiranga
spellingShingle Escosteguy,Claudia Caminha
Carvalho,Marciano de Almeida
Medronho,Roberto de Andrade
Abreu,Luiz Maurino
Monteiro Filho,Mario Ypiranga
Bundle branch and atrioventricular block as complications of acute myocardial infarction in the thrombolytic era
author_facet Escosteguy,Claudia Caminha
Carvalho,Marciano de Almeida
Medronho,Roberto de Andrade
Abreu,Luiz Maurino
Monteiro Filho,Mario Ypiranga
author_sort Escosteguy,Claudia Caminha
title Bundle branch and atrioventricular block as complications of acute myocardial infarction in the thrombolytic era
title_short Bundle branch and atrioventricular block as complications of acute myocardial infarction in the thrombolytic era
title_full Bundle branch and atrioventricular block as complications of acute myocardial infarction in the thrombolytic era
title_fullStr Bundle branch and atrioventricular block as complications of acute myocardial infarction in the thrombolytic era
title_full_unstemmed Bundle branch and atrioventricular block as complications of acute myocardial infarction in the thrombolytic era
title_sort bundle branch and atrioventricular block as complications of acute myocardial infarction in the thrombolytic era
description OBJECTIVE: To analyze the incidence of intraventricular and atrioventricular conduction defects associated with acute myocardial infarction and the degree of in hospital mortality resulting from this condition during the era of thrombolytic therapy. METHODS: Observational study of a cohort of 929 consecutive patients with acute myocardial infarction. Multivariate analysis by logistic regression. Was used. RESULTS: Logistic regression showed a greater incidence of bundle branch block in male sex (odds ratio = 1.87, 95% CI = 1.02-3.42), age over 70 years (odds ratio = 2.31, 95% CI = 1.68-5.00), anterior localization of the infarction (odds ratio = 1.93, 95% CI = 1.03-3.65). There was a greater incidence of complete atrioventricular block in inferior infarcts (odds ratio = 2.59, 95% CI 1.30-5.18) and the presence of cardiogenic shock (odds ratio = 3.90, 95% CI = 1.43-10.65). Use of a thrombolytic agent was associated with a tendency toward a lower occurrence of bundle branch block (odds ratio = 0.68) and a greater occurrence of complete atrioventricular block (odds ratio = 1.44). The presence of bundle branch block (odds ratio = 2.45 95% , CI = 1.14-5.28) and of complete atrioventricular block (odds ratio = 13.59, 95% CI = 5.43-33.98) was associated with a high and independent probability of inhospital death. CONCLUSION: During the current era of thrombolytic therapy and in this population, intraventricular disturbances of electrical conduction and complete atrioventricular block were associated with a high and independent risk of inhospital death during acute myocardial infarction.
publisher Sociedade Brasileira de Cardiologia - SBC
publishDate 2001
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2001000400003
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