Critical analysis of the allocation policy for liver transplantation in Brazil

Liver transplantation is now the standard treatment for end-stage liver disease. Given the shortage of liver donors and the progressively higher number of patients waiting for transplantation, improvements in patient selection and optimization of timing for transplantation are needed. Several solutions have been suggested, including increasing the donor pool; a fair policy for allocation, not permitting variables such as age, gender, and race, or third-party payer status to play any role; and knowledge of the natural history of each liver disease for which transplantation is offered. To observe ethical rules and distributive justice (guarantee to every citizen the same opportunity to get an organ), the "sickest first" policy must be used. Studies have demonstrated that death has no relationship with waiting time, but rather with the severity of liver disease at the time of inclusion. Thus, waiting time is no longer part of the United Network for Organ Sharing distribution criteria. Waiting time only differentiates between equally severely diseased patients. The authors have analyzed the waiting list mortality and 1-year survival for patients of the State of São Paulo, from July 1997 through January 2001. Only the chronological criterion was used. According to "Secretaria de Estado da Saúde de São Paulo" data, among all waiting list deaths, 82.2% occurred within the first year, and 37.6% within the first 3 months following inclusion. The allocation of livers based on waiting time is neither fair nor ethical, impairs distributive justice and human rights, and does not occur in any other part of the world.

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Main Authors: Sette Jr.,Hoel, Bacchella,Telesforo, Machado,Marcel Cerqueira César
Format: Digital revista
Language:English
Published: Faculdade de Medicina / Universidade de São Paulo - FM/USP 2003
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0041-87812003000300009
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spelling oai:scielo:S0041-878120030003000092003-07-22Critical analysis of the allocation policy for liver transplantation in BrazilSette Jr.,HoelBacchella,TelesforoMachado,Marcel Cerqueira César Liver transplant Allocation criteria Survival prognostic models Liver transplantation is now the standard treatment for end-stage liver disease. Given the shortage of liver donors and the progressively higher number of patients waiting for transplantation, improvements in patient selection and optimization of timing for transplantation are needed. Several solutions have been suggested, including increasing the donor pool; a fair policy for allocation, not permitting variables such as age, gender, and race, or third-party payer status to play any role; and knowledge of the natural history of each liver disease for which transplantation is offered. To observe ethical rules and distributive justice (guarantee to every citizen the same opportunity to get an organ), the "sickest first" policy must be used. Studies have demonstrated that death has no relationship with waiting time, but rather with the severity of liver disease at the time of inclusion. Thus, waiting time is no longer part of the United Network for Organ Sharing distribution criteria. Waiting time only differentiates between equally severely diseased patients. The authors have analyzed the waiting list mortality and 1-year survival for patients of the State of São Paulo, from July 1997 through January 2001. Only the chronological criterion was used. According to "Secretaria de Estado da Saúde de São Paulo" data, among all waiting list deaths, 82.2% occurred within the first year, and 37.6% within the first 3 months following inclusion. The allocation of livers based on waiting time is neither fair nor ethical, impairs distributive justice and human rights, and does not occur in any other part of the world.info:eu-repo/semantics/openAccessFaculdade de Medicina / Universidade de São Paulo - FM/USPRevista do Hospital das Clínicas v.58 n.3 20032003-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0041-87812003000300009en10.1590/S0041-87812003000300009
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Sette Jr.,Hoel
Bacchella,Telesforo
Machado,Marcel Cerqueira César
spellingShingle Sette Jr.,Hoel
Bacchella,Telesforo
Machado,Marcel Cerqueira César
Critical analysis of the allocation policy for liver transplantation in Brazil
author_facet Sette Jr.,Hoel
Bacchella,Telesforo
Machado,Marcel Cerqueira César
author_sort Sette Jr.,Hoel
title Critical analysis of the allocation policy for liver transplantation in Brazil
title_short Critical analysis of the allocation policy for liver transplantation in Brazil
title_full Critical analysis of the allocation policy for liver transplantation in Brazil
title_fullStr Critical analysis of the allocation policy for liver transplantation in Brazil
title_full_unstemmed Critical analysis of the allocation policy for liver transplantation in Brazil
title_sort critical analysis of the allocation policy for liver transplantation in brazil
description Liver transplantation is now the standard treatment for end-stage liver disease. Given the shortage of liver donors and the progressively higher number of patients waiting for transplantation, improvements in patient selection and optimization of timing for transplantation are needed. Several solutions have been suggested, including increasing the donor pool; a fair policy for allocation, not permitting variables such as age, gender, and race, or third-party payer status to play any role; and knowledge of the natural history of each liver disease for which transplantation is offered. To observe ethical rules and distributive justice (guarantee to every citizen the same opportunity to get an organ), the "sickest first" policy must be used. Studies have demonstrated that death has no relationship with waiting time, but rather with the severity of liver disease at the time of inclusion. Thus, waiting time is no longer part of the United Network for Organ Sharing distribution criteria. Waiting time only differentiates between equally severely diseased patients. The authors have analyzed the waiting list mortality and 1-year survival for patients of the State of São Paulo, from July 1997 through January 2001. Only the chronological criterion was used. According to "Secretaria de Estado da Saúde de São Paulo" data, among all waiting list deaths, 82.2% occurred within the first year, and 37.6% within the first 3 months following inclusion. The allocation of livers based on waiting time is neither fair nor ethical, impairs distributive justice and human rights, and does not occur in any other part of the world.
publisher Faculdade de Medicina / Universidade de São Paulo - FM/USP
publishDate 2003
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0041-87812003000300009
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