Antineoplastic properties and pharmacological applications of Crotalus durissus terrificus snake venom

Antineoplastic properties and pharmacological applications of Crotalus durissus terrificus snake venom

ABSTRACT Snake toxins are widely studied owing to their importance in snakebite accidents, a serious public health issue in tropical countries, and their broad therapeutic potential. Isolated fractions from venom produced by snakes of the genus Crotalus sp. present a wide variety of pharmacological uses such as antifungal, antiviral, antibacterial, and antitumor properties, among other therapeutic potentialities. Given the direct effect of this venom on tumor cells, isolation of its compounds is important for the characterization of its anticarcinogenic actions. Crotalus durissus terrificus venom and its toxins have been widely evaluated as potential candidates for the development of new antineoplastic therapies that are efficient against different tumor lines and cellular targets. This review highlights the venom toxins of this species, with a focus on their antineoplastic properties.

Saved in:
Bibliographic Details
Main Authors: Alves,Brunna Fernanda Arraez, Ferreira Jr,Rui Seabra
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Medicina Tropical - SBMT 2022
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822022000100207
Tags: Add Tag
No Tags, Be the first to tag this record!
id oai:scielo:S0037-86822022000100207
record_format ojs
spelling oai:scielo:S0037-868220220001002072022-12-13Antineoplastic properties and pharmacological applications of Crotalus durissus terrificus snake venomAlves,Brunna Fernanda ArraezFerreira Jr,Rui Seabra Snake Venom Cancer Antitumor Crotalid Venoms Crotalus ABSTRACT Snake toxins are widely studied owing to their importance in snakebite accidents, a serious public health issue in tropical countries, and their broad therapeutic potential. Isolated fractions from venom produced by snakes of the genus Crotalus sp. present a wide variety of pharmacological uses such as antifungal, antiviral, antibacterial, and antitumor properties, among other therapeutic potentialities. Given the direct effect of this venom on tumor cells, isolation of its compounds is important for the characterization of its anticarcinogenic actions. Crotalus durissus terrificus venom and its toxins have been widely evaluated as potential candidates for the development of new antineoplastic therapies that are efficient against different tumor lines and cellular targets. This review highlights the venom toxins of this species, with a focus on their antineoplastic properties.info:eu-repo/semantics/openAccessSociedade Brasileira de Medicina Tropical - SBMTRevista da Sociedade Brasileira de Medicina Tropical v.55 20222022-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822022000100207en10.1590/0037-8682-0323-2022
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Alves,Brunna Fernanda Arraez
Ferreira Jr,Rui Seabra
spellingShingle Alves,Brunna Fernanda Arraez
Ferreira Jr,Rui Seabra
Antineoplastic properties and pharmacological applications of Crotalus durissus terrificus snake venom
author_facet Alves,Brunna Fernanda Arraez
Ferreira Jr,Rui Seabra
author_sort Alves,Brunna Fernanda Arraez
title Antineoplastic properties and pharmacological applications of Crotalus durissus terrificus snake venom
title_short Antineoplastic properties and pharmacological applications of Crotalus durissus terrificus snake venom
title_full Antineoplastic properties and pharmacological applications of Crotalus durissus terrificus snake venom
title_fullStr Antineoplastic properties and pharmacological applications of Crotalus durissus terrificus snake venom
title_full_unstemmed Antineoplastic properties and pharmacological applications of Crotalus durissus terrificus snake venom
title_sort antineoplastic properties and pharmacological applications of crotalus durissus terrificus snake venom
description ABSTRACT Snake toxins are widely studied owing to their importance in snakebite accidents, a serious public health issue in tropical countries, and their broad therapeutic potential. Isolated fractions from venom produced by snakes of the genus Crotalus sp. present a wide variety of pharmacological uses such as antifungal, antiviral, antibacterial, and antitumor properties, among other therapeutic potentialities. Given the direct effect of this venom on tumor cells, isolation of its compounds is important for the characterization of its anticarcinogenic actions. Crotalus durissus terrificus venom and its toxins have been widely evaluated as potential candidates for the development of new antineoplastic therapies that are efficient against different tumor lines and cellular targets. This review highlights the venom toxins of this species, with a focus on their antineoplastic properties.
publisher Sociedade Brasileira de Medicina Tropical - SBMT
publishDate 2022
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822022000100207
work_keys_str_mv AT alvesbrunnafernandaarraez antineoplasticpropertiesandpharmacologicalapplicationsofcrotalusdurissusterrificussnakevenom
AT ferreirajrruiseabra antineoplasticpropertiesandpharmacologicalapplicationsofcrotalusdurissusterrificussnakevenom
_version_ 1756472186449690624

Similar Items