Estimated mortality rate and leading causes of death among individuals with chikungunya in 2016 and 2017 in Brazil
Abstract INTRODUCTION: In 2014, the first cases of autochthonous chikungunya (CHIK) were recorded in Brazil. Lethality associated with this disease is underestimated. Thus, this study aimed to analyze the causes of death among individuals with CHIK in Brazil. METHODS: A descriptive observational study was conducted on individuals with CHIK who died within 6 months from symptom onset. Data pairing between the Information System for Notifiable Diseases and the Mortality Information System was performed. Deaths were classified according to case confirmation criterion, mention of CHIK in the death certificates (DCs), and disease phase. The lethality rate per 1,000 cases was corrected for underreporting and was estimated according to region, sex, age, years of education, race/color, and cause groups. RESULTS: We identified 3,135 deaths (mention of CHIK in the DCs, 764 [24.4%]). In 17.6% of these cases, CHIK was the underlying cause. Most deaths occurred in the acute (38.1%) and post-acute (29.6%) phases. The corrected LR (5.7; x1,000) was 6.8 times higher than that obtained from the Information System for Notifiable Diseases (0.8). The highest corrected LRs were estimated for among individuals living in the Northeast region (6.2), men (7.4), those with low years of education and those aged <1 year (8.6), 65-79 years (20.7), and ≥80 years (75.4). CONCLUSIONS: The LR of CHIK estimates based on information system linkage help to reveal the relevance of this disease as the direct cause or as a cause associated with serious or fatal events, provide timely interventions, and increase the knowledge about this disease.
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Sociedade Brasileira de Medicina Tropical - SBMT
2020
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oai:scielo:S0037-868220200001003162020-04-13Estimated mortality rate and leading causes of death among individuals with chikungunya in 2016 and 2017 in BrazilFrutuoso,Livia Carla VinhalFreitas,André Ricardo RibasCavalcanti,Luciano Pamplona de GóesDuarte,Elisabeth Carmen Chikungunya fever Mortality Matched-pair analysis Death certificate Abstract INTRODUCTION: In 2014, the first cases of autochthonous chikungunya (CHIK) were recorded in Brazil. Lethality associated with this disease is underestimated. Thus, this study aimed to analyze the causes of death among individuals with CHIK in Brazil. METHODS: A descriptive observational study was conducted on individuals with CHIK who died within 6 months from symptom onset. Data pairing between the Information System for Notifiable Diseases and the Mortality Information System was performed. Deaths were classified according to case confirmation criterion, mention of CHIK in the death certificates (DCs), and disease phase. The lethality rate per 1,000 cases was corrected for underreporting and was estimated according to region, sex, age, years of education, race/color, and cause groups. RESULTS: We identified 3,135 deaths (mention of CHIK in the DCs, 764 [24.4%]). In 17.6% of these cases, CHIK was the underlying cause. Most deaths occurred in the acute (38.1%) and post-acute (29.6%) phases. The corrected LR (5.7; x1,000) was 6.8 times higher than that obtained from the Information System for Notifiable Diseases (0.8). The highest corrected LRs were estimated for among individuals living in the Northeast region (6.2), men (7.4), those with low years of education and those aged <1 year (8.6), 65-79 years (20.7), and ≥80 years (75.4). CONCLUSIONS: The LR of CHIK estimates based on information system linkage help to reveal the relevance of this disease as the direct cause or as a cause associated with serious or fatal events, provide timely interventions, and increase the knowledge about this disease.info:eu-repo/semantics/openAccessSociedade Brasileira de Medicina Tropical - SBMTRevista da Sociedade Brasileira de Medicina Tropical v.53 20202020-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100316en10.1590/0037-8682-0580-2019 |
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Frutuoso,Livia Carla Vinhal Freitas,André Ricardo Ribas Cavalcanti,Luciano Pamplona de Góes Duarte,Elisabeth Carmen |
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Frutuoso,Livia Carla Vinhal Freitas,André Ricardo Ribas Cavalcanti,Luciano Pamplona de Góes Duarte,Elisabeth Carmen Estimated mortality rate and leading causes of death among individuals with chikungunya in 2016 and 2017 in Brazil |
author_facet |
Frutuoso,Livia Carla Vinhal Freitas,André Ricardo Ribas Cavalcanti,Luciano Pamplona de Góes Duarte,Elisabeth Carmen |
author_sort |
Frutuoso,Livia Carla Vinhal |
title |
Estimated mortality rate and leading causes of death among individuals with chikungunya in 2016 and 2017 in Brazil |
title_short |
Estimated mortality rate and leading causes of death among individuals with chikungunya in 2016 and 2017 in Brazil |
title_full |
Estimated mortality rate and leading causes of death among individuals with chikungunya in 2016 and 2017 in Brazil |
title_fullStr |
Estimated mortality rate and leading causes of death among individuals with chikungunya in 2016 and 2017 in Brazil |
title_full_unstemmed |
Estimated mortality rate and leading causes of death among individuals with chikungunya in 2016 and 2017 in Brazil |
title_sort |
estimated mortality rate and leading causes of death among individuals with chikungunya in 2016 and 2017 in brazil |
description |
Abstract INTRODUCTION: In 2014, the first cases of autochthonous chikungunya (CHIK) were recorded in Brazil. Lethality associated with this disease is underestimated. Thus, this study aimed to analyze the causes of death among individuals with CHIK in Brazil. METHODS: A descriptive observational study was conducted on individuals with CHIK who died within 6 months from symptom onset. Data pairing between the Information System for Notifiable Diseases and the Mortality Information System was performed. Deaths were classified according to case confirmation criterion, mention of CHIK in the death certificates (DCs), and disease phase. The lethality rate per 1,000 cases was corrected for underreporting and was estimated according to region, sex, age, years of education, race/color, and cause groups. RESULTS: We identified 3,135 deaths (mention of CHIK in the DCs, 764 [24.4%]). In 17.6% of these cases, CHIK was the underlying cause. Most deaths occurred in the acute (38.1%) and post-acute (29.6%) phases. The corrected LR (5.7; x1,000) was 6.8 times higher than that obtained from the Information System for Notifiable Diseases (0.8). The highest corrected LRs were estimated for among individuals living in the Northeast region (6.2), men (7.4), those with low years of education and those aged <1 year (8.6), 65-79 years (20.7), and ≥80 years (75.4). CONCLUSIONS: The LR of CHIK estimates based on information system linkage help to reveal the relevance of this disease as the direct cause or as a cause associated with serious or fatal events, provide timely interventions, and increase the knowledge about this disease. |
publisher |
Sociedade Brasileira de Medicina Tropical - SBMT |
publishDate |
2020 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100316 |
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