Predictive factors for Leishmania infantum infection in dogs examined at a veterinary teaching hospital in Teresina, State of Piauí, Brazil

Abstract: INTRODUCTION: In Brazil, culling of seropositive dogs is one of the recommended strategies to control visceral leishmaniasis. Since infectiousness is correlated with clinical signs, control measures targeting symptomatic dogs could be more effective. METHODS: A cross-sectional study was carried out among 1,410 dogs, predictive models were developed based on clinical signs and an indirect immunofluorescence antibody test. RESULTS: The validated predictive model showed sensitivity and specificity of 86.5% and 70.0%, respectively. CONCLUSIONS: Predictive models could be used as tools to aid control programs in focusing on a smaller fraction of dogs contributing more to infection dissemination.

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Main Authors: Gouvêa,Marcus Vinicius, Mendonça,Ivete Lopes, Cruz,Maria do Socorro Pires e, Costa,Carlos Henrique Nery, Braga,José Ueleres, Werneck,Guilherme Loureiro
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Medicina Tropical - SBMT 2016
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000100107
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spelling oai:scielo:S0037-868220160001001072016-03-15Predictive factors for Leishmania infantum infection in dogs examined at a veterinary teaching hospital in Teresina, State of Piauí, BrazilGouvêa,Marcus ViniciusMendonça,Ivete LopesCruz,Maria do Socorro Pires eCosta,Carlos Henrique NeryBraga,José UeleresWerneck,Guilherme Loureiro Canine Control measures Visceral leishmaniasis Abstract: INTRODUCTION: In Brazil, culling of seropositive dogs is one of the recommended strategies to control visceral leishmaniasis. Since infectiousness is correlated with clinical signs, control measures targeting symptomatic dogs could be more effective. METHODS: A cross-sectional study was carried out among 1,410 dogs, predictive models were developed based on clinical signs and an indirect immunofluorescence antibody test. RESULTS: The validated predictive model showed sensitivity and specificity of 86.5% and 70.0%, respectively. CONCLUSIONS: Predictive models could be used as tools to aid control programs in focusing on a smaller fraction of dogs contributing more to infection dissemination.info:eu-repo/semantics/openAccessSociedade Brasileira de Medicina Tropical - SBMTRevista da Sociedade Brasileira de Medicina Tropical v.49 n.1 20162016-02-01info:eu-repo/semantics/othertext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000100107en10.1590/0037-8682-0187-2015
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country Brasil
countrycode BR
component Revista
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databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Gouvêa,Marcus Vinicius
Mendonça,Ivete Lopes
Cruz,Maria do Socorro Pires e
Costa,Carlos Henrique Nery
Braga,José Ueleres
Werneck,Guilherme Loureiro
spellingShingle Gouvêa,Marcus Vinicius
Mendonça,Ivete Lopes
Cruz,Maria do Socorro Pires e
Costa,Carlos Henrique Nery
Braga,José Ueleres
Werneck,Guilherme Loureiro
Predictive factors for Leishmania infantum infection in dogs examined at a veterinary teaching hospital in Teresina, State of Piauí, Brazil
author_facet Gouvêa,Marcus Vinicius
Mendonça,Ivete Lopes
Cruz,Maria do Socorro Pires e
Costa,Carlos Henrique Nery
Braga,José Ueleres
Werneck,Guilherme Loureiro
author_sort Gouvêa,Marcus Vinicius
title Predictive factors for Leishmania infantum infection in dogs examined at a veterinary teaching hospital in Teresina, State of Piauí, Brazil
title_short Predictive factors for Leishmania infantum infection in dogs examined at a veterinary teaching hospital in Teresina, State of Piauí, Brazil
title_full Predictive factors for Leishmania infantum infection in dogs examined at a veterinary teaching hospital in Teresina, State of Piauí, Brazil
title_fullStr Predictive factors for Leishmania infantum infection in dogs examined at a veterinary teaching hospital in Teresina, State of Piauí, Brazil
title_full_unstemmed Predictive factors for Leishmania infantum infection in dogs examined at a veterinary teaching hospital in Teresina, State of Piauí, Brazil
title_sort predictive factors for leishmania infantum infection in dogs examined at a veterinary teaching hospital in teresina, state of piauí, brazil
description Abstract: INTRODUCTION: In Brazil, culling of seropositive dogs is one of the recommended strategies to control visceral leishmaniasis. Since infectiousness is correlated with clinical signs, control measures targeting symptomatic dogs could be more effective. METHODS: A cross-sectional study was carried out among 1,410 dogs, predictive models were developed based on clinical signs and an indirect immunofluorescence antibody test. RESULTS: The validated predictive model showed sensitivity and specificity of 86.5% and 70.0%, respectively. CONCLUSIONS: Predictive models could be used as tools to aid control programs in focusing on a smaller fraction of dogs contributing more to infection dissemination.
publisher Sociedade Brasileira de Medicina Tropical - SBMT
publishDate 2016
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000100107
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