Acetylcholinesterase inhibition starting from extracts of Bauhinia variegata L., Bauhinia var. candida (Aiton) Buch.-Ham., and Bauhinia ungulata L

INTRODUCTION: A treatment to the Alzheimer's disease consists inhibition of the acetylcholinesterase, which is responsible for the acetylcholine control in the synapses. METHODS: We have investigated the potential of inhibition of the acetylcholinesterase produced by hexane extracts of leaves, branches, and flowers from three Bauhinia specimens, which is based on the technique of thin layer chromatography and on identifying the organ of the plant that possesses larger concentration of inhibitors. RESULTS: Retention factor analysis shows values of 0.31aA, 0.31aA, and 0.46aB for flowers B. variegata, B. var. candida, and B. ungulata, respectively. CONCLUSIONS: The flower extract of B. ungulata is the most suitable for further studies on this inhibition.

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Bibliographic Details
Main Authors: Santos,Kamilla Monteiro dos, Gonçalves,Priscila Sant'Ana, Paiva,Maria José Nunes de, Lacerda,Guilherme Araújo
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Medicina Tropical - SBMT 2011
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000600025
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