Absence of clinical abnormalities suggesting renal involvement during the long-term course of visceral Leishmaniasis

Abnormalities of renal function have been demonstrated inpatients with visceral leishmaniasis; although there was a trend toward normalization following antiparasitic therapy, some abnormalities persisted. With thepurpose of studying the long- term clinical course of renal involvement in visceral leishmaniasis, 32 patients with a diagnosis of this parasitic disease were evaluated in the endemic area and at least 6 months after the clinical cure of the disease and compared with a control group of 28 individuals. No patient had a history or clinical findings suggestive of renal disease and all were normotensive. Laboratory evaluation was normal in all except 3 patients with abnormal urinalysis. Mild proteinuria and microscopic hematuria were seen in a single urinalysis in one patient (although three other urinalysis were normal), and leucocyturia in two female patients. It was concluded that the renal involvement in visceral leishmaniasis is mild and transient, with normal renal function observed on long-term follow-up after cure of the parasitic infection.

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Main Authors: Martinelli,Reinaldo, Lorenço,Rosemarie, Rocha,Heonir
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Medicina Tropical - SBMT 1986
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821986000400002
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spelling oai:scielo:S0037-868219860004000022013-06-06Absence of clinical abnormalities suggesting renal involvement during the long-term course of visceral LeishmaniasisMartinelli,ReinaldoLorenço,RosemarieRocha,Heonir Visceral leishmaniasis Nephropathy Reversibility Clinical Course Parasitic disease Abnormalities of renal function have been demonstrated inpatients with visceral leishmaniasis; although there was a trend toward normalization following antiparasitic therapy, some abnormalities persisted. With thepurpose of studying the long- term clinical course of renal involvement in visceral leishmaniasis, 32 patients with a diagnosis of this parasitic disease were evaluated in the endemic area and at least 6 months after the clinical cure of the disease and compared with a control group of 28 individuals. No patient had a history or clinical findings suggestive of renal disease and all were normotensive. Laboratory evaluation was normal in all except 3 patients with abnormal urinalysis. Mild proteinuria and microscopic hematuria were seen in a single urinalysis in one patient (although three other urinalysis were normal), and leucocyturia in two female patients. It was concluded that the renal involvement in visceral leishmaniasis is mild and transient, with normal renal function observed on long-term follow-up after cure of the parasitic infection.info:eu-repo/semantics/openAccessSociedade Brasileira de Medicina Tropical - SBMTRevista da Sociedade Brasileira de Medicina Tropical v.19 n.4 19861986-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821986000400002en10.1590/S0037-86821986000400002
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Martinelli,Reinaldo
Lorenço,Rosemarie
Rocha,Heonir
spellingShingle Martinelli,Reinaldo
Lorenço,Rosemarie
Rocha,Heonir
Absence of clinical abnormalities suggesting renal involvement during the long-term course of visceral Leishmaniasis
author_facet Martinelli,Reinaldo
Lorenço,Rosemarie
Rocha,Heonir
author_sort Martinelli,Reinaldo
title Absence of clinical abnormalities suggesting renal involvement during the long-term course of visceral Leishmaniasis
title_short Absence of clinical abnormalities suggesting renal involvement during the long-term course of visceral Leishmaniasis
title_full Absence of clinical abnormalities suggesting renal involvement during the long-term course of visceral Leishmaniasis
title_fullStr Absence of clinical abnormalities suggesting renal involvement during the long-term course of visceral Leishmaniasis
title_full_unstemmed Absence of clinical abnormalities suggesting renal involvement during the long-term course of visceral Leishmaniasis
title_sort absence of clinical abnormalities suggesting renal involvement during the long-term course of visceral leishmaniasis
description Abnormalities of renal function have been demonstrated inpatients with visceral leishmaniasis; although there was a trend toward normalization following antiparasitic therapy, some abnormalities persisted. With thepurpose of studying the long- term clinical course of renal involvement in visceral leishmaniasis, 32 patients with a diagnosis of this parasitic disease were evaluated in the endemic area and at least 6 months after the clinical cure of the disease and compared with a control group of 28 individuals. No patient had a history or clinical findings suggestive of renal disease and all were normotensive. Laboratory evaluation was normal in all except 3 patients with abnormal urinalysis. Mild proteinuria and microscopic hematuria were seen in a single urinalysis in one patient (although three other urinalysis were normal), and leucocyturia in two female patients. It was concluded that the renal involvement in visceral leishmaniasis is mild and transient, with normal renal function observed on long-term follow-up after cure of the parasitic infection.
publisher Sociedade Brasileira de Medicina Tropical - SBMT
publishDate 1986
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821986000400002
work_keys_str_mv AT martinellireinaldo absenceofclinicalabnormalitiessuggestingrenalinvolvementduringthelongtermcourseofvisceralleishmaniasis
AT lorencorosemarie absenceofclinicalabnormalitiessuggestingrenalinvolvementduringthelongtermcourseofvisceralleishmaniasis
AT rochaheonir absenceofclinicalabnormalitiessuggestingrenalinvolvementduringthelongtermcourseofvisceralleishmaniasis
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