Efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in Chagas' disease

Efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in Chagas' disease

The osmotic threshold for vasopressin release was studied in normal patients (n = 7) and in patients with the chronic form of Chagas'disease (n = 11). Positive correlation between osmotic threshold and plasma cortisol concentration was obtained for the Controls (y1 = 273,30 + 0,75x i; r = 0,78;P < 0,05), suggesting a modulating effect of cortisol on vasopressin release. The lack of correlation between the two parameters for the chronic chagasic patients was interpreted, on the basis of the general denervation associated with Chagas ' disease, to be the result of neuronal destruction in hypothalamic and/or extrahypothalamic centers related to the secretory control of vasopressin.

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Main Authors: Kimachi,Tatsuto, Veiga,Joel P. R., Lima-Filho,Euclydes C.
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Medicina Tropical - SBMT 1983
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821983000300003
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spelling oai:scielo:S0037-868219830003000032013-06-10Efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in Chagas' diseaseKimachi,TatsutoVeiga,Joel P. R.Lima-Filho,Euclydes C. Plasma Cortisol Concentration Osmotic Threshold Vasopressin Release Chronic Chagas' Disease The osmotic threshold for vasopressin release was studied in normal patients (n = 7) and in patients with the chronic form of Chagas'disease (n = 11). Positive correlation between osmotic threshold and plasma cortisol concentration was obtained for the Controls (y1 = 273,30 + 0,75x i; r = 0,78;P < 0,05), suggesting a modulating effect of cortisol on vasopressin release. The lack of correlation between the two parameters for the chronic chagasic patients was interpreted, on the basis of the general denervation associated with Chagas ' disease, to be the result of neuronal destruction in hypothalamic and/or extrahypothalamic centers related to the secretory control of vasopressin.info:eu-repo/semantics/openAccessSociedade Brasileira de Medicina Tropical - SBMTRevista da Sociedade Brasileira de Medicina Tropical v.16 n.3 19831983-09-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821983000300003en10.1590/S0037-86821983000300003
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Kimachi,Tatsuto
Veiga,Joel P. R.
Lima-Filho,Euclydes C.
spellingShingle Kimachi,Tatsuto
Veiga,Joel P. R.
Lima-Filho,Euclydes C.
Efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in Chagas' disease
author_facet Kimachi,Tatsuto
Veiga,Joel P. R.
Lima-Filho,Euclydes C.
author_sort Kimachi,Tatsuto
title Efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in Chagas' disease
title_short Efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in Chagas' disease
title_full Efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in Chagas' disease
title_fullStr Efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in Chagas' disease
title_full_unstemmed Efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in Chagas' disease
title_sort efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in chagas' disease
description The osmotic threshold for vasopressin release was studied in normal patients (n = 7) and in patients with the chronic form of Chagas'disease (n = 11). Positive correlation between osmotic threshold and plasma cortisol concentration was obtained for the Controls (y1 = 273,30 + 0,75x i; r = 0,78;P < 0,05), suggesting a modulating effect of cortisol on vasopressin release. The lack of correlation between the two parameters for the chronic chagasic patients was interpreted, on the basis of the general denervation associated with Chagas ' disease, to be the result of neuronal destruction in hypothalamic and/or extrahypothalamic centers related to the secretory control of vasopressin.
publisher Sociedade Brasileira de Medicina Tropical - SBMT
publishDate 1983
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821983000300003
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AT veigajoelpr efectsofplasmacorticosteroidconcentrationontheosmoticthresholdforvasopressinreleasinginchagasdisease
AT limafilhoeuclydesc efectsofplasmacorticosteroidconcentrationontheosmoticthresholdforvasopressinreleasinginchagasdisease
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