ASSOCIATION OF EPSTEIN-BARR VIRUS (EBV) BUT NOT HUMAN PAPILLOMAVIRUS (HPV) WITH GINGIVITIS AND/OR PERIODONTITIS IN TRANSPLANTED INDIVIDUALS
SUMMARY The aim of this study was to investigate the association of EBV and HPV with gingivitis and/or periodontitis according to the immunologic status. To this end, 74 oral biopsies from transplanted and non-transplanted individuals with the abovementioned oral manifestations were submitted to a screening by PCR for both viruses. According to the results, EBV was strongly associated with gingivitis and/or periodontitis in transplanted individuals (p = 0.011) but not HPV (p = 0.766). EBV-HPV co-detections did not enhance the presence of tissue injury as well. Although a causal relationship was not investigated in this study, the higher frequency of these two oncoviruses in lesion tissues must be investigated in follow-up studies, especially among immunocompromised individuals.
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Instituto de Medicina Tropical de São Paulo
2016
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oai:scielo:S0036-466520160050005032016-07-07ASSOCIATION OF EPSTEIN-BARR VIRUS (EBV) BUT NOT HUMAN PAPILLOMAVIRUS (HPV) WITH GINGIVITIS AND/OR PERIODONTITIS IN TRANSPLANTED INDIVIDUALSBAEZ,Camila FrezeSAVASSI-RIBAS,FlaviaROCHA,Wilker Menezes daALMEIDA,Stéphanie G. S.GONÇALVES,Marianna T. V.GUIMARÃES,Maria Angelica A. M.CAVALCANTI,Silvia Maria B.VARELLA,Rafael B. HPV EBV Oral cavity Kidney transplant SUMMARY The aim of this study was to investigate the association of EBV and HPV with gingivitis and/or periodontitis according to the immunologic status. To this end, 74 oral biopsies from transplanted and non-transplanted individuals with the abovementioned oral manifestations were submitted to a screening by PCR for both viruses. According to the results, EBV was strongly associated with gingivitis and/or periodontitis in transplanted individuals (p = 0.011) but not HPV (p = 0.766). EBV-HPV co-detections did not enhance the presence of tissue injury as well. Although a causal relationship was not investigated in this study, the higher frequency of these two oncoviruses in lesion tissues must be investigated in follow-up studies, especially among immunocompromised individuals.info:eu-repo/semantics/openAccessInstituto de Medicina Tropical de São PauloRevista do Instituto de Medicina Tropical de São Paulo v.58 20162016-01-01info:eu-repo/semantics/othertext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652016005000503en10.1590/S1678-9946201658058 |
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BAEZ,Camila Freze SAVASSI-RIBAS,Flavia ROCHA,Wilker Menezes da ALMEIDA,Stéphanie G. S. GONÇALVES,Marianna T. V. GUIMARÃES,Maria Angelica A. M. CAVALCANTI,Silvia Maria B. VARELLA,Rafael B. |
spellingShingle |
BAEZ,Camila Freze SAVASSI-RIBAS,Flavia ROCHA,Wilker Menezes da ALMEIDA,Stéphanie G. S. GONÇALVES,Marianna T. V. GUIMARÃES,Maria Angelica A. M. CAVALCANTI,Silvia Maria B. VARELLA,Rafael B. ASSOCIATION OF EPSTEIN-BARR VIRUS (EBV) BUT NOT HUMAN PAPILLOMAVIRUS (HPV) WITH GINGIVITIS AND/OR PERIODONTITIS IN TRANSPLANTED INDIVIDUALS |
author_facet |
BAEZ,Camila Freze SAVASSI-RIBAS,Flavia ROCHA,Wilker Menezes da ALMEIDA,Stéphanie G. S. GONÇALVES,Marianna T. V. GUIMARÃES,Maria Angelica A. M. CAVALCANTI,Silvia Maria B. VARELLA,Rafael B. |
author_sort |
BAEZ,Camila Freze |
title |
ASSOCIATION OF EPSTEIN-BARR VIRUS (EBV) BUT NOT HUMAN PAPILLOMAVIRUS (HPV) WITH GINGIVITIS AND/OR PERIODONTITIS IN TRANSPLANTED INDIVIDUALS |
title_short |
ASSOCIATION OF EPSTEIN-BARR VIRUS (EBV) BUT NOT HUMAN PAPILLOMAVIRUS (HPV) WITH GINGIVITIS AND/OR PERIODONTITIS IN TRANSPLANTED INDIVIDUALS |
title_full |
ASSOCIATION OF EPSTEIN-BARR VIRUS (EBV) BUT NOT HUMAN PAPILLOMAVIRUS (HPV) WITH GINGIVITIS AND/OR PERIODONTITIS IN TRANSPLANTED INDIVIDUALS |
title_fullStr |
ASSOCIATION OF EPSTEIN-BARR VIRUS (EBV) BUT NOT HUMAN PAPILLOMAVIRUS (HPV) WITH GINGIVITIS AND/OR PERIODONTITIS IN TRANSPLANTED INDIVIDUALS |
title_full_unstemmed |
ASSOCIATION OF EPSTEIN-BARR VIRUS (EBV) BUT NOT HUMAN PAPILLOMAVIRUS (HPV) WITH GINGIVITIS AND/OR PERIODONTITIS IN TRANSPLANTED INDIVIDUALS |
title_sort |
association of epstein-barr virus (ebv) but not human papillomavirus (hpv) with gingivitis and/or periodontitis in transplanted individuals |
description |
SUMMARY The aim of this study was to investigate the association of EBV and HPV with gingivitis and/or periodontitis according to the immunologic status. To this end, 74 oral biopsies from transplanted and non-transplanted individuals with the abovementioned oral manifestations were submitted to a screening by PCR for both viruses. According to the results, EBV was strongly associated with gingivitis and/or periodontitis in transplanted individuals (p = 0.011) but not HPV (p = 0.766). EBV-HPV co-detections did not enhance the presence of tissue injury as well. Although a causal relationship was not investigated in this study, the higher frequency of these two oncoviruses in lesion tissues must be investigated in follow-up studies, especially among immunocompromised individuals. |
publisher |
Instituto de Medicina Tropical de São Paulo |
publishDate |
2016 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652016005000503 |
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