ASSOCIATION OF EPSTEIN-BARR VIRUS (EBV) BUT NOT HUMAN PAPILLOMAVIRUS (HPV) WITH GINGIVITIS AND/OR PERIODONTITIS IN TRANSPLANTED INDIVIDUALS

SUMMARY The aim of this study was to investigate the association of EBV and HPV with gingivitis and/or periodontitis according to the immunologic status. To this end, 74 oral biopsies from transplanted and non-transplanted individuals with the abovementioned oral manifestations were submitted to a screening by PCR for both viruses. According to the results, EBV was strongly associated with gingivitis and/or periodontitis in transplanted individuals (p = 0.011) but not HPV (p = 0.766). EBV-HPV co-detections did not enhance the presence of tissue injury as well. Although a causal relationship was not investigated in this study, the higher frequency of these two oncoviruses in lesion tissues must be investigated in follow-up studies, especially among immunocompromised individuals.

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Main Authors: BAEZ,Camila Freze, SAVASSI-RIBAS,Flavia, ROCHA,Wilker Menezes da, ALMEIDA,Stéphanie G. S., GONÇALVES,Marianna T. V., GUIMARÃES,Maria Angelica A. M., CAVALCANTI,Silvia Maria B., VARELLA,Rafael B.
Format: Digital revista
Language:English
Published: Instituto de Medicina Tropical de São Paulo 2016
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652016005000503
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spelling oai:scielo:S0036-466520160050005032016-07-07ASSOCIATION OF EPSTEIN-BARR VIRUS (EBV) BUT NOT HUMAN PAPILLOMAVIRUS (HPV) WITH GINGIVITIS AND/OR PERIODONTITIS IN TRANSPLANTED INDIVIDUALSBAEZ,Camila FrezeSAVASSI-RIBAS,FlaviaROCHA,Wilker Menezes daALMEIDA,Stéphanie G. S.GONÇALVES,Marianna T. V.GUIMARÃES,Maria Angelica A. M.CAVALCANTI,Silvia Maria B.VARELLA,Rafael B. HPV EBV Oral cavity Kidney transplant SUMMARY The aim of this study was to investigate the association of EBV and HPV with gingivitis and/or periodontitis according to the immunologic status. To this end, 74 oral biopsies from transplanted and non-transplanted individuals with the abovementioned oral manifestations were submitted to a screening by PCR for both viruses. According to the results, EBV was strongly associated with gingivitis and/or periodontitis in transplanted individuals (p = 0.011) but not HPV (p = 0.766). EBV-HPV co-detections did not enhance the presence of tissue injury as well. Although a causal relationship was not investigated in this study, the higher frequency of these two oncoviruses in lesion tissues must be investigated in follow-up studies, especially among immunocompromised individuals.info:eu-repo/semantics/openAccessInstituto de Medicina Tropical de São PauloRevista do Instituto de Medicina Tropical de São Paulo v.58 20162016-01-01info:eu-repo/semantics/othertext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652016005000503en10.1590/S1678-9946201658058
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libraryname SciELO
language English
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author BAEZ,Camila Freze
SAVASSI-RIBAS,Flavia
ROCHA,Wilker Menezes da
ALMEIDA,Stéphanie G. S.
GONÇALVES,Marianna T. V.
GUIMARÃES,Maria Angelica A. M.
CAVALCANTI,Silvia Maria B.
VARELLA,Rafael B.
spellingShingle BAEZ,Camila Freze
SAVASSI-RIBAS,Flavia
ROCHA,Wilker Menezes da
ALMEIDA,Stéphanie G. S.
GONÇALVES,Marianna T. V.
GUIMARÃES,Maria Angelica A. M.
CAVALCANTI,Silvia Maria B.
VARELLA,Rafael B.
ASSOCIATION OF EPSTEIN-BARR VIRUS (EBV) BUT NOT HUMAN PAPILLOMAVIRUS (HPV) WITH GINGIVITIS AND/OR PERIODONTITIS IN TRANSPLANTED INDIVIDUALS
author_facet BAEZ,Camila Freze
SAVASSI-RIBAS,Flavia
ROCHA,Wilker Menezes da
ALMEIDA,Stéphanie G. S.
GONÇALVES,Marianna T. V.
GUIMARÃES,Maria Angelica A. M.
CAVALCANTI,Silvia Maria B.
VARELLA,Rafael B.
author_sort BAEZ,Camila Freze
title ASSOCIATION OF EPSTEIN-BARR VIRUS (EBV) BUT NOT HUMAN PAPILLOMAVIRUS (HPV) WITH GINGIVITIS AND/OR PERIODONTITIS IN TRANSPLANTED INDIVIDUALS
title_short ASSOCIATION OF EPSTEIN-BARR VIRUS (EBV) BUT NOT HUMAN PAPILLOMAVIRUS (HPV) WITH GINGIVITIS AND/OR PERIODONTITIS IN TRANSPLANTED INDIVIDUALS
title_full ASSOCIATION OF EPSTEIN-BARR VIRUS (EBV) BUT NOT HUMAN PAPILLOMAVIRUS (HPV) WITH GINGIVITIS AND/OR PERIODONTITIS IN TRANSPLANTED INDIVIDUALS
title_fullStr ASSOCIATION OF EPSTEIN-BARR VIRUS (EBV) BUT NOT HUMAN PAPILLOMAVIRUS (HPV) WITH GINGIVITIS AND/OR PERIODONTITIS IN TRANSPLANTED INDIVIDUALS
title_full_unstemmed ASSOCIATION OF EPSTEIN-BARR VIRUS (EBV) BUT NOT HUMAN PAPILLOMAVIRUS (HPV) WITH GINGIVITIS AND/OR PERIODONTITIS IN TRANSPLANTED INDIVIDUALS
title_sort association of epstein-barr virus (ebv) but not human papillomavirus (hpv) with gingivitis and/or periodontitis in transplanted individuals
description SUMMARY The aim of this study was to investigate the association of EBV and HPV with gingivitis and/or periodontitis according to the immunologic status. To this end, 74 oral biopsies from transplanted and non-transplanted individuals with the abovementioned oral manifestations were submitted to a screening by PCR for both viruses. According to the results, EBV was strongly associated with gingivitis and/or periodontitis in transplanted individuals (p = 0.011) but not HPV (p = 0.766). EBV-HPV co-detections did not enhance the presence of tissue injury as well. Although a causal relationship was not investigated in this study, the higher frequency of these two oncoviruses in lesion tissues must be investigated in follow-up studies, especially among immunocompromised individuals.
publisher Instituto de Medicina Tropical de São Paulo
publishDate 2016
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652016005000503
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