Chronic disseminated histoplasmosis with lesions restricted to the mouth: case report

We report a rare case of chronic disseminated histoplasmosis with several ulcerated lesions in the oral cavity in an alcoholic patient without human immunodeficiency virus infection, with no detectable signs and symptoms of systemic disease or extraoral manifestations. Histopathological analysis revealed chronic inflammatory process with granulomas containing Histoplasma-like organisms. The isolation of Histoplasma capsulatum provided the definitive diagnosis. Treatment with itraconazole resulted in complete remission of oral lesions. As far we aware, this is the second case report of oral histoplasmosis in an HIV negative patient described in Brazil.

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Main Authors: Valle,Antonio Carlos F. do, Moreira,Luiz Carlos, Almeida-Paes,Rodrigo, Moreira,João S., Pizzini,Cláudia V., Muniz,Mauro de Medeiros, Zancopé-Oliveira,Rosely M.
Format: Digital revista
Language:English
Published: Instituto de Medicina Tropical de São Paulo 2006
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652006000200012
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spelling oai:scielo:S0036-466520060002000122006-05-08Chronic disseminated histoplasmosis with lesions restricted to the mouth: case reportValle,Antonio Carlos F. doMoreira,Luiz CarlosAlmeida-Paes,RodrigoMoreira,João S.Pizzini,Cláudia V.Muniz,Mauro de MedeirosZancopé-Oliveira,Rosely M. Histoplasmosis Oral lesions Fungal disease We report a rare case of chronic disseminated histoplasmosis with several ulcerated lesions in the oral cavity in an alcoholic patient without human immunodeficiency virus infection, with no detectable signs and symptoms of systemic disease or extraoral manifestations. Histopathological analysis revealed chronic inflammatory process with granulomas containing Histoplasma-like organisms. The isolation of Histoplasma capsulatum provided the definitive diagnosis. Treatment with itraconazole resulted in complete remission of oral lesions. As far we aware, this is the second case report of oral histoplasmosis in an HIV negative patient described in Brazil.info:eu-repo/semantics/openAccessInstituto de Medicina Tropical de São PauloRevista do Instituto de Medicina Tropical de São Paulo v.48 n.2 20062006-04-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652006000200012en10.1590/S0036-46652006000200012
institution SCIELO
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country Brasil
countrycode BR
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libraryname SciELO
language English
format Digital
author Valle,Antonio Carlos F. do
Moreira,Luiz Carlos
Almeida-Paes,Rodrigo
Moreira,João S.
Pizzini,Cláudia V.
Muniz,Mauro de Medeiros
Zancopé-Oliveira,Rosely M.
spellingShingle Valle,Antonio Carlos F. do
Moreira,Luiz Carlos
Almeida-Paes,Rodrigo
Moreira,João S.
Pizzini,Cláudia V.
Muniz,Mauro de Medeiros
Zancopé-Oliveira,Rosely M.
Chronic disseminated histoplasmosis with lesions restricted to the mouth: case report
author_facet Valle,Antonio Carlos F. do
Moreira,Luiz Carlos
Almeida-Paes,Rodrigo
Moreira,João S.
Pizzini,Cláudia V.
Muniz,Mauro de Medeiros
Zancopé-Oliveira,Rosely M.
author_sort Valle,Antonio Carlos F. do
title Chronic disseminated histoplasmosis with lesions restricted to the mouth: case report
title_short Chronic disseminated histoplasmosis with lesions restricted to the mouth: case report
title_full Chronic disseminated histoplasmosis with lesions restricted to the mouth: case report
title_fullStr Chronic disseminated histoplasmosis with lesions restricted to the mouth: case report
title_full_unstemmed Chronic disseminated histoplasmosis with lesions restricted to the mouth: case report
title_sort chronic disseminated histoplasmosis with lesions restricted to the mouth: case report
description We report a rare case of chronic disseminated histoplasmosis with several ulcerated lesions in the oral cavity in an alcoholic patient without human immunodeficiency virus infection, with no detectable signs and symptoms of systemic disease or extraoral manifestations. Histopathological analysis revealed chronic inflammatory process with granulomas containing Histoplasma-like organisms. The isolation of Histoplasma capsulatum provided the definitive diagnosis. Treatment with itraconazole resulted in complete remission of oral lesions. As far we aware, this is the second case report of oral histoplasmosis in an HIV negative patient described in Brazil.
publisher Instituto de Medicina Tropical de São Paulo
publishDate 2006
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652006000200012
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