Central nervous system virion detection in acute measles: histopathological, ultrastructural and pathogenetic aspects
Histopathological and ultrastructural studies of 23 patients who died with clinical diagnosis of measles were carried out. In 12 cases viral nucleocapsids were searched by electron microscopy and detected in 100% of the cases in the lungs and in 50% of the cases in the central nervous system. They were mostly intranuclear. Histopathological changes associated to neurological alterations and the detection of virion are discussed in relation to acute and delayed clinical manifestations.
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Instituto de Medicina Tropical de São Paulo
1995
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oai:scielo:S0036-466519950002000082007-02-22Central nervous system virion detection in acute measles: histopathological, ultrastructural and pathogenetic aspectsLancellotti,C.L.P.Corbett,C.E.P.Duarte,M.I.S. Measles Virus Central Nervous System Pathology Ultrastructure Pathogenesis Histopathological and ultrastructural studies of 23 patients who died with clinical diagnosis of measles were carried out. In 12 cases viral nucleocapsids were searched by electron microscopy and detected in 100% of the cases in the lungs and in 50% of the cases in the central nervous system. They were mostly intranuclear. Histopathological changes associated to neurological alterations and the detection of virion are discussed in relation to acute and delayed clinical manifestations.info:eu-repo/semantics/openAccessInstituto de Medicina Tropical de São PauloRevista do Instituto de Medicina Tropical de São Paulo v.37 n.2 19951995-04-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651995000200008en10.1590/S0036-46651995000200008 |
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| author |
Lancellotti,C.L.P. Corbett,C.E.P. Duarte,M.I.S. |
| spellingShingle |
Lancellotti,C.L.P. Corbett,C.E.P. Duarte,M.I.S. Central nervous system virion detection in acute measles: histopathological, ultrastructural and pathogenetic aspects |
| author_facet |
Lancellotti,C.L.P. Corbett,C.E.P. Duarte,M.I.S. |
| author_sort |
Lancellotti,C.L.P. |
| title |
Central nervous system virion detection in acute measles: histopathological, ultrastructural and pathogenetic aspects |
| title_short |
Central nervous system virion detection in acute measles: histopathological, ultrastructural and pathogenetic aspects |
| title_full |
Central nervous system virion detection in acute measles: histopathological, ultrastructural and pathogenetic aspects |
| title_fullStr |
Central nervous system virion detection in acute measles: histopathological, ultrastructural and pathogenetic aspects |
| title_full_unstemmed |
Central nervous system virion detection in acute measles: histopathological, ultrastructural and pathogenetic aspects |
| title_sort |
central nervous system virion detection in acute measles: histopathological, ultrastructural and pathogenetic aspects |
| description |
Histopathological and ultrastructural studies of 23 patients who died with clinical diagnosis of measles were carried out. In 12 cases viral nucleocapsids were searched by electron microscopy and detected in 100% of the cases in the lungs and in 50% of the cases in the central nervous system. They were mostly intranuclear. Histopathological changes associated to neurological alterations and the detection of virion are discussed in relation to acute and delayed clinical manifestations. |
| publisher |
Instituto de Medicina Tropical de São Paulo |
| publishDate |
1995 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651995000200008 |
| work_keys_str_mv |
AT lancellotticlp centralnervoussystemviriondetectioninacutemeasleshistopathologicalultrastructuralandpathogeneticaspects AT corbettcep centralnervoussystemviriondetectioninacutemeasleshistopathologicalultrastructuralandpathogeneticaspects AT duartemis centralnervoussystemviriondetectioninacutemeasleshistopathologicalultrastructuralandpathogeneticaspects |
| _version_ |
1756379652480303104 |