Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis

Total serum IgE, and Strongyloides - specific IgG and IgA antibodies were studied in 27 patients with parasitologically proven strongyloidiasis. Clinical manifestations in this case series were investigated by a restrospective study of the patient's records. Total serum IgE levels were elevated (greater than 250 IU/ml) in 59% of the patients (mean concentration = 1364 IU/ml). Parasite - specific IgG and IgA antibodies were detected by ELISA in the serum of 23 (85.2%) and 21 (77.8%) patients, respectively. Elevated serum IgE and clinical manifestations were not useful indexes of the presence of strongyloidiasis. On the other hand, our results support the view that serologic tests, particularly ELISA for detecting Strongyloides - specific IgG antibodies, can be usefully exploited for diagnostic purposes in strongyloidiasis.

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Main Authors: Rossi,Cláudio L., Takahashi,Emilia E. H., Partel,Cláudia D., Teodoro,Lívia G.V.L., Silva,Luiz J. da
Format: Digital revista
Language:English
Published: Instituto de Medicina Tropical de São Paulo 1993
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651993000400010
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spelling oai:scielo:S0036-466519930004000102006-07-21Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasisRossi,Cláudio L.Takahashi,Emilia E. H.Partel,Cláudia D.Teodoro,Lívia G.V.L.Silva,Luiz J. da Strongyloides stercoralis Strongyloidiasis Immunodiagnosis Total serum IgE, and Strongyloides - specific IgG and IgA antibodies were studied in 27 patients with parasitologically proven strongyloidiasis. Clinical manifestations in this case series were investigated by a restrospective study of the patient's records. Total serum IgE levels were elevated (greater than 250 IU/ml) in 59% of the patients (mean concentration = 1364 IU/ml). Parasite - specific IgG and IgA antibodies were detected by ELISA in the serum of 23 (85.2%) and 21 (77.8%) patients, respectively. Elevated serum IgE and clinical manifestations were not useful indexes of the presence of strongyloidiasis. On the other hand, our results support the view that serologic tests, particularly ELISA for detecting Strongyloides - specific IgG antibodies, can be usefully exploited for diagnostic purposes in strongyloidiasis.info:eu-repo/semantics/openAccessInstituto de Medicina Tropical de São PauloRevista do Instituto de Medicina Tropical de São Paulo v.35 n.4 19931993-08-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651993000400010en10.1590/S0036-46651993000400010
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libraryname SciELO
language English
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author Rossi,Cláudio L.
Takahashi,Emilia E. H.
Partel,Cláudia D.
Teodoro,Lívia G.V.L.
Silva,Luiz J. da
spellingShingle Rossi,Cláudio L.
Takahashi,Emilia E. H.
Partel,Cláudia D.
Teodoro,Lívia G.V.L.
Silva,Luiz J. da
Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis
author_facet Rossi,Cláudio L.
Takahashi,Emilia E. H.
Partel,Cláudia D.
Teodoro,Lívia G.V.L.
Silva,Luiz J. da
author_sort Rossi,Cláudio L.
title Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis
title_short Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis
title_full Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis
title_fullStr Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis
title_full_unstemmed Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis
title_sort total serum ige and parasite: specific igg and iga antibodies in human strongyloidiasis
description Total serum IgE, and Strongyloides - specific IgG and IgA antibodies were studied in 27 patients with parasitologically proven strongyloidiasis. Clinical manifestations in this case series were investigated by a restrospective study of the patient's records. Total serum IgE levels were elevated (greater than 250 IU/ml) in 59% of the patients (mean concentration = 1364 IU/ml). Parasite - specific IgG and IgA antibodies were detected by ELISA in the serum of 23 (85.2%) and 21 (77.8%) patients, respectively. Elevated serum IgE and clinical manifestations were not useful indexes of the presence of strongyloidiasis. On the other hand, our results support the view that serologic tests, particularly ELISA for detecting Strongyloides - specific IgG antibodies, can be usefully exploited for diagnostic purposes in strongyloidiasis.
publisher Instituto de Medicina Tropical de São Paulo
publishDate 1993
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651993000400010
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