"In vitro" activity of gentian violet against asexual Plasmodium falciparum parasites
In order to investigate whether gentian violet exhibited "in vitro" inhibitory activity against Plasmodium falciparum, the Authors have carried out 20 sensitivity tests according to the microtechnique described by RIECK MANN et al.5. Results have shown inhibition of schizonts'maturation at the following concentration: 1/1000; 1/1500; 1/2000; 1/2500; 1/3000 and 1/4000, thus demonstrating inhibitory activity of the tested dye against asexual blood parasites. The present data suggest gentain violet may be possibly used in the prophylaxis of transfusion-acquired malaria.
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Main Authors: | Yang,Shen Lin, Di Santi,Silvia Maria, Amato Neto,Vicente, Moreira,Antonio Augusto Baillot, Pinto,Pedro Luiz Silva, Boulos,Marcos, Campos,Rubens, Sant'Ana,Eunice José de, Shiroma,Mario |
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Format: | Digital revista |
Language: | English |
Published: |
Instituto de Medicina Tropical de São Paulo
1988
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Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651988000100003 |
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