Trasplante de microbiota fecal por colonoscopía en paciente mayor de 65 años con infección recurrente de Clostridioides difficile: aún una estrategia subutilizada

Trasplante de microbiota fecal por colonoscopía en paciente mayor de 65 años con infección recurrente de Clostridioides difficile: aún una estrategia subutilizada

Clostridioides difficile infection (CDI) is a major public health problem and responsible for significant morbidity and mortality. Eighty percent of CDIs occur in adults older than 65 years of age due to a decreased gastrointestinal microbial diversity, immunosenescence and frailty. Thus, the most reported risk factor for recurrent CDI is older age since nearly 60% of cases occur in individuals aged ≥ 65 years. Fecal microbiota transplantation (FMT) is a highly cost-effective alternative to antibiotic treatment for patients with recurrent CDI. We report a 75-year-old male with recurrent CDI, who received a FMT after several unsuccessful antimicrobial treatments. He had a satisfactory evolution after the procedure and remained without diarrhea during the ensuing five months.

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Bibliographic Details
Main Authors: Núñez,Paulina, Quera,Rodrigo, Von Muhlenbrock,Christian, Concha,Alexandra, Flores,Katherine
Format: Digital revista
Language:Spanish / Castilian
Published: Sociedad Médica de Santiago 2022
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872022001001396
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id oai:scielo:S0034-98872022001001396
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spelling oai:scielo:S0034-988720220010013962023-04-24Trasplante de microbiota fecal por colonoscopía en paciente mayor de 65 años con infección recurrente de Clostridioides difficile: aún una estrategia subutilizadaNúñez,PaulinaQuera,RodrigoVon Muhlenbrock,ChristianConcha,AlexandraFlores,Katherine Aged Clostridioides difficile Fecal Microbiota Transplantation Fidaxomicin Recurrence Clostridioides difficile infection (CDI) is a major public health problem and responsible for significant morbidity and mortality. Eighty percent of CDIs occur in adults older than 65 years of age due to a decreased gastrointestinal microbial diversity, immunosenescence and frailty. Thus, the most reported risk factor for recurrent CDI is older age since nearly 60% of cases occur in individuals aged ≥ 65 years. Fecal microbiota transplantation (FMT) is a highly cost-effective alternative to antibiotic treatment for patients with recurrent CDI. We report a 75-year-old male with recurrent CDI, who received a FMT after several unsuccessful antimicrobial treatments. He had a satisfactory evolution after the procedure and remained without diarrhea during the ensuing five months.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.150 n.10 20222022-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872022001001396es10.4067/S0034-98872022001001396
institution SCIELO
collection OJS
country Chile
countrycode CL
component Revista
access En linea
databasecode rev-scielo-cl
tag revista
region America del Sur
libraryname SciELO
language Spanish / Castilian
format Digital
author Núñez,Paulina
Quera,Rodrigo
Von Muhlenbrock,Christian
Concha,Alexandra
Flores,Katherine
spellingShingle Núñez,Paulina
Quera,Rodrigo
Von Muhlenbrock,Christian
Concha,Alexandra
Flores,Katherine
Trasplante de microbiota fecal por colonoscopía en paciente mayor de 65 años con infección recurrente de Clostridioides difficile: aún una estrategia subutilizada
author_facet Núñez,Paulina
Quera,Rodrigo
Von Muhlenbrock,Christian
Concha,Alexandra
Flores,Katherine
author_sort Núñez,Paulina
title Trasplante de microbiota fecal por colonoscopía en paciente mayor de 65 años con infección recurrente de Clostridioides difficile: aún una estrategia subutilizada
title_short Trasplante de microbiota fecal por colonoscopía en paciente mayor de 65 años con infección recurrente de Clostridioides difficile: aún una estrategia subutilizada
title_full Trasplante de microbiota fecal por colonoscopía en paciente mayor de 65 años con infección recurrente de Clostridioides difficile: aún una estrategia subutilizada
title_fullStr Trasplante de microbiota fecal por colonoscopía en paciente mayor de 65 años con infección recurrente de Clostridioides difficile: aún una estrategia subutilizada
title_full_unstemmed Trasplante de microbiota fecal por colonoscopía en paciente mayor de 65 años con infección recurrente de Clostridioides difficile: aún una estrategia subutilizada
title_sort trasplante de microbiota fecal por colonoscopía en paciente mayor de 65 años con infección recurrente de clostridioides difficile: aún una estrategia subutilizada
description Clostridioides difficile infection (CDI) is a major public health problem and responsible for significant morbidity and mortality. Eighty percent of CDIs occur in adults older than 65 years of age due to a decreased gastrointestinal microbial diversity, immunosenescence and frailty. Thus, the most reported risk factor for recurrent CDI is older age since nearly 60% of cases occur in individuals aged ≥ 65 years. Fecal microbiota transplantation (FMT) is a highly cost-effective alternative to antibiotic treatment for patients with recurrent CDI. We report a 75-year-old male with recurrent CDI, who received a FMT after several unsuccessful antimicrobial treatments. He had a satisfactory evolution after the procedure and remained without diarrhea during the ensuing five months.
publisher Sociedad Médica de Santiago
publishDate 2022
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872022001001396
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AT querarodrigo trasplantedemicrobiotafecalporcolonoscopiaenpacientemayorde65anosconinfeccionrecurrentedeclostridioidesdifficileaununaestrategiasubutilizada
AT vonmuhlenbrockchristian trasplantedemicrobiotafecalporcolonoscopiaenpacientemayorde65anosconinfeccionrecurrentedeclostridioidesdifficileaununaestrategiasubutilizada
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