COVID-19, shock séptico refractario y terapia extracorpórea de purificación sanguínea con OXIRIS®

Sepsis is one of the leading causes of death in critically ill patients with COVID-19 and blood purification therapies have a role to immunomodulate the excessive inflammatory response and improve clinical results. One of the devices designed for these therapies is the oXiris® filter, allowing to perform renal replacement therapy combined with selective adsorption of endotoxins and cytokines. We report a 55-year-old male with COVID who developed a septic shock secondary to a sepsis caused by Pseudomona aeruginosa, refractory to the usual management. A veno-venous continuous hemofiltration was started using the oXiris® filter for 48 hours. Subsequently, there was an improvement in clinical perfusion parameters and a reduction in inflammatory markers. The patient was discharged from the intensive care one month later.

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Main Authors: Ramírez-Guerrero,Gonzalo, Baghetti-Hernández,Romyna, Godoy-Tello,Cristian, Villagrán-Cortés,Francisco, Torres-Cifuentes,Vicente, Garay-Coloma,Osvaldo
Format: Digital revista
Language:Spanish / Castilian
Published: Sociedad Médica de Santiago 2022
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872022000200266
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spelling oai:scielo:S0034-988720220002002662022-11-28COVID-19, shock séptico refractario y terapia extracorpórea de purificación sanguínea con OXIRIS®Ramírez-Guerrero,GonzaloBaghetti-Hernández,RomynaGodoy-Tello,CristianVillagrán-Cortés,FranciscoTorres-Cifuentes,VicenteGaray-Coloma,Osvaldo Adsorption Continuous Renal Replacement Therapy Cytokines Cytokine Release Syndrome Shock, Septic Sepsis is one of the leading causes of death in critically ill patients with COVID-19 and blood purification therapies have a role to immunomodulate the excessive inflammatory response and improve clinical results. One of the devices designed for these therapies is the oXiris® filter, allowing to perform renal replacement therapy combined with selective adsorption of endotoxins and cytokines. We report a 55-year-old male with COVID who developed a septic shock secondary to a sepsis caused by Pseudomona aeruginosa, refractory to the usual management. A veno-venous continuous hemofiltration was started using the oXiris® filter for 48 hours. Subsequently, there was an improvement in clinical perfusion parameters and a reduction in inflammatory markers. The patient was discharged from the intensive care one month later.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.150 n.2 20222022-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872022000200266es10.4067/S0034-98872022000200266
institution SCIELO
collection OJS
country Chile
countrycode CL
component Revista
access En linea
databasecode rev-scielo-cl
tag revista
region America del Sur
libraryname SciELO
language Spanish / Castilian
format Digital
author Ramírez-Guerrero,Gonzalo
Baghetti-Hernández,Romyna
Godoy-Tello,Cristian
Villagrán-Cortés,Francisco
Torres-Cifuentes,Vicente
Garay-Coloma,Osvaldo
spellingShingle Ramírez-Guerrero,Gonzalo
Baghetti-Hernández,Romyna
Godoy-Tello,Cristian
Villagrán-Cortés,Francisco
Torres-Cifuentes,Vicente
Garay-Coloma,Osvaldo
COVID-19, shock séptico refractario y terapia extracorpórea de purificación sanguínea con OXIRIS®
author_facet Ramírez-Guerrero,Gonzalo
Baghetti-Hernández,Romyna
Godoy-Tello,Cristian
Villagrán-Cortés,Francisco
Torres-Cifuentes,Vicente
Garay-Coloma,Osvaldo
author_sort Ramírez-Guerrero,Gonzalo
title COVID-19, shock séptico refractario y terapia extracorpórea de purificación sanguínea con OXIRIS®
title_short COVID-19, shock séptico refractario y terapia extracorpórea de purificación sanguínea con OXIRIS®
title_full COVID-19, shock séptico refractario y terapia extracorpórea de purificación sanguínea con OXIRIS®
title_fullStr COVID-19, shock séptico refractario y terapia extracorpórea de purificación sanguínea con OXIRIS®
title_full_unstemmed COVID-19, shock séptico refractario y terapia extracorpórea de purificación sanguínea con OXIRIS®
title_sort covid-19, shock séptico refractario y terapia extracorpórea de purificación sanguínea con oxiris®
description Sepsis is one of the leading causes of death in critically ill patients with COVID-19 and blood purification therapies have a role to immunomodulate the excessive inflammatory response and improve clinical results. One of the devices designed for these therapies is the oXiris® filter, allowing to perform renal replacement therapy combined with selective adsorption of endotoxins and cytokines. We report a 55-year-old male with COVID who developed a septic shock secondary to a sepsis caused by Pseudomona aeruginosa, refractory to the usual management. A veno-venous continuous hemofiltration was started using the oXiris® filter for 48 hours. Subsequently, there was an improvement in clinical perfusion parameters and a reduction in inflammatory markers. The patient was discharged from the intensive care one month later.
publisher Sociedad Médica de Santiago
publishDate 2022
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872022000200266
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