Desensibilización a pirfenidona. Caso clínico

Desensibilización a pirfenidona. Caso clínico

We report a 68-year-old woman with a history of idiopathic pulmonary fibrosis, who had immediate skin reactions associated with the use of pirfenidone in two opportunities. In the evaluation by immunology, an allergy to pirfenidone was diagnosed. Given the urgent need for the drug, a desensitization procedure was started. The dose of the medication was increased progressively, previous premedication with cetirizine, ranitidine and montelukast. After this procedure the patient was able to tolerate the treatment with pirfenidone without cutaneous reactions.

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Bibliographic Details
Main Authors: Bastías O.,Carla, Reyes C.,Felipe, Rodriguez M.,Karla, Díaz B.,Ilennee
Format: Digital revista
Language:Spanish / Castilian
Published: Sociedad Médica de Santiago 2021
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021001001512
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spelling oai:scielo:S0034-988720210010015122022-03-15Desensibilización a pirfenidona. Caso clínicoBastías O.,CarlaReyes C.,FelipeRodriguez M.,KarlaDíaz B.,Ilennee Drug Hypersensitivity Exanthema Pulmonary Fibrosis We report a 68-year-old woman with a history of idiopathic pulmonary fibrosis, who had immediate skin reactions associated with the use of pirfenidone in two opportunities. In the evaluation by immunology, an allergy to pirfenidone was diagnosed. Given the urgent need for the drug, a desensitization procedure was started. The dose of the medication was increased progressively, previous premedication with cetirizine, ranitidine and montelukast. After this procedure the patient was able to tolerate the treatment with pirfenidone without cutaneous reactions.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.149 n.10 20212021-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021001001512es10.4067/s0034-98872021001001512
institution SCIELO
collection OJS
country Chile
countrycode CL
component Revista
access En linea
databasecode rev-scielo-cl
tag revista
region America del Sur
libraryname SciELO
language Spanish / Castilian
format Digital
author Bastías O.,Carla
Reyes C.,Felipe
Rodriguez M.,Karla
Díaz B.,Ilennee
spellingShingle Bastías O.,Carla
Reyes C.,Felipe
Rodriguez M.,Karla
Díaz B.,Ilennee
Desensibilización a pirfenidona. Caso clínico
author_facet Bastías O.,Carla
Reyes C.,Felipe
Rodriguez M.,Karla
Díaz B.,Ilennee
author_sort Bastías O.,Carla
title Desensibilización a pirfenidona. Caso clínico
title_short Desensibilización a pirfenidona. Caso clínico
title_full Desensibilización a pirfenidona. Caso clínico
title_fullStr Desensibilización a pirfenidona. Caso clínico
title_full_unstemmed Desensibilización a pirfenidona. Caso clínico
title_sort desensibilización a pirfenidona. caso clínico
description We report a 68-year-old woman with a history of idiopathic pulmonary fibrosis, who had immediate skin reactions associated with the use of pirfenidone in two opportunities. In the evaluation by immunology, an allergy to pirfenidone was diagnosed. Given the urgent need for the drug, a desensitization procedure was started. The dose of the medication was increased progressively, previous premedication with cetirizine, ranitidine and montelukast. After this procedure the patient was able to tolerate the treatment with pirfenidone without cutaneous reactions.
publisher Sociedad Médica de Santiago
publishDate 2021
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021001001512
work_keys_str_mv AT bastiasocarla desensibilizacionapirfenidonacasoclinico
AT reyescfelipe desensibilizacionapirfenidonacasoclinico
AT rodriguezmkarla desensibilizacionapirfenidonacasoclinico
AT diazbilennee desensibilizacionapirfenidonacasoclinico
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