Resultados del primer registro chileno de angina inestable: características clínicas, perfil de riesgo y tratamiento

Background: From January 2000 to June 2002, the first Chilean registry of unstable angina was carried out, with the participation of 15 hospitals. Aim: To report the clinical and demographic features of 600 patients with unstable angina, their risk profile and prognosis. Material and methods: The inclusion criteria for this prospective registry were a history of recent onset of chest pain (<48 hours) or a change in the character of previous angina, associated to ischemic electrocardiographic changes and/or positive markers of myocardial damage. Results: Mean age of the patients was 65 years and 37% were women. Among coronary risk factors, 63% had hypertension, 27% had diabetes, 52% had dyslipidemia, 31% smoked and 21% had a family history of atherosclerosis. On admission 94% of patients had chest pain, associated to ST segment depression in 44%, negative T waves in 28% and positive markers of myocardial damage in 30%. Fifty seven percent received intravenous nitroglycerin, 47% received oral nitrates, 69% beta blockers and 15%, calcium antagonists. Antithrombotic therapy included aspirin in 96%, heparin in 74%, ticlodipine or clopidogrel in 19% and IIb/IIIa inhibitors in 12%. A coronary angiogram was performed in 52%, angioplasty in 25% and coronary bypass surgery in 13%. Hospital mortality was 2.6%. The incidence of new ischemic events was: myocardial infarction in 2.8% recurrent ischemia in 9.5% and refractory ischemia in 2%. The incidence of adverse events increased according to a higher risk profile. Conclusions: The demographic and clinical features, treatment and mortality of these patients are similar to those reported in international registries, with a low mortality rate (Rev Méd Chile 2004; 132: 135-43)

Bibliographic Details

Main Authors:	Corbalán H,Ramón, Nazzal N,Carolina, Eggers R,Germán, Bartolucci J,Jaime, Prieto D,Juan Carlos, Alcaíno I,Milton, Stockins F,Benjamín, Campos P,Pabla, Dapelo A,Alejandro
Format:	Digital revista
Language:	Spanish / Castilian
Published:	Sociedad Médica de Santiago 2004
Online Access:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000200001
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