Diabetes mellitus inducida por olanzapina: Caso clínico
Atypical antipsychotics are widely used in psychotic disorders, refractory to conventional neuroleptic agents. They induce minimal extra pyramidal side effects, probably due to their greater affinity for certain dopaminergic receptors. However, this polyreceptor affinity may be responsible for the development of other side effects. We report a 48 years old male drinker and addicted to cocaine, that after two months of Olanzapine use, developed a severe diabetes mellitus with fasting blood glucose values reaching 514 mg/dl. When he was admitted to the hospital, physical examination was normal and his body mass index was 28 kg/m2. Olanzapine was discontinued and blood glucose values gradually returned to normal. After two months of follow up, the patient is on dietary treatment and with a fasting glucose of 132 mg/dl (Rev Méd Chile 2001; 129: 1183-85)
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Sociedad Médica de Santiago
2001
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oai:scielo:S0034-988720010010000112005-11-14Diabetes mellitus inducida por olanzapina: Caso clínicoRojas G,PaulaArancibia S,PabloBravo S,VerónicaVarela G,Susana Antipsychotic Agents Diabetes Mellitus Drug Toxicity Atypical antipsychotics are widely used in psychotic disorders, refractory to conventional neuroleptic agents. They induce minimal extra pyramidal side effects, probably due to their greater affinity for certain dopaminergic receptors. However, this polyreceptor affinity may be responsible for the development of other side effects. We report a 48 years old male drinker and addicted to cocaine, that after two months of Olanzapine use, developed a severe diabetes mellitus with fasting blood glucose values reaching 514 mg/dl. When he was admitted to the hospital, physical examination was normal and his body mass index was 28 kg/m2. Olanzapine was discontinued and blood glucose values gradually returned to normal. After two months of follow up, the patient is on dietary treatment and with a fasting glucose of 132 mg/dl (Rev Méd Chile 2001; 129: 1183-85)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.129 n.10 20012001-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001000011es10.4067/S0034-98872001001000011 |
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Rojas G,Paula Arancibia S,Pablo Bravo S,Verónica Varela G,Susana |
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Rojas G,Paula Arancibia S,Pablo Bravo S,Verónica Varela G,Susana Diabetes mellitus inducida por olanzapina: Caso clínico |
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Rojas G,Paula Arancibia S,Pablo Bravo S,Verónica Varela G,Susana |
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Rojas G,Paula |
title |
Diabetes mellitus inducida por olanzapina: Caso clínico |
title_short |
Diabetes mellitus inducida por olanzapina: Caso clínico |
title_full |
Diabetes mellitus inducida por olanzapina: Caso clínico |
title_fullStr |
Diabetes mellitus inducida por olanzapina: Caso clínico |
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Diabetes mellitus inducida por olanzapina: Caso clínico |
title_sort |
diabetes mellitus inducida por olanzapina: caso clínico |
description |
Atypical antipsychotics are widely used in psychotic disorders, refractory to conventional neuroleptic agents. They induce minimal extra pyramidal side effects, probably due to their greater affinity for certain dopaminergic receptors. However, this polyreceptor affinity may be responsible for the development of other side effects. We report a 48 years old male drinker and addicted to cocaine, that after two months of Olanzapine use, developed a severe diabetes mellitus with fasting blood glucose values reaching 514 mg/dl. When he was admitted to the hospital, physical examination was normal and his body mass index was 28 kg/m2. Olanzapine was discontinued and blood glucose values gradually returned to normal. After two months of follow up, the patient is on dietary treatment and with a fasting glucose of 132 mg/dl (Rev Méd Chile 2001; 129: 1183-85) |
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Sociedad Médica de Santiago |
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2001 |
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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001000011 |
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