Synthesis, characterization and antibacterial screening of some Schiff bases derived from pyrazole and 4-amino antipyrine

Synthesis, characterization and antibacterial screening of some Schiff bases derived from pyrazole and 4-amino antipyrine

Some Schiff bases of pyrazole and 4-amino antipyrine have been synthesized. The antibacterial screening of these synthesized compounds was done in dimethyl forma-mide against four Gram positive bacteria viz. Bacillus cereus, Staphylococcus aureus, Staphylococcus epidermidids and Micrococcus luteus, and three Gram negative bacteria viz. Proteus mirabilis, Escherichia coli and Klebsiella aerogenes. It is observed that in comparison to Schiff bases of 4-amino antipyrine, pyrazole Schiff bases are better for inhibition for these selected Gram positive and Gram negative bacterial strains.

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Main Authors: Baluja,Shipra, Chanda,Sumitra
Format: Digital revista
Language:English
Published: Departamento de Farmácia, Facultad de Ciencias, Universidade Nacional da Colombia 2016
Online Access:http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0034-74182016000200002
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spelling oai:scielo:S0034-741820160002000022017-03-03Synthesis, characterization and antibacterial screening of some Schiff bases derived from pyrazole and 4-amino antipyrineBaluja,ShipraChanda,Sumitra 4-amino antipyrine Schiff bases dimethyl formamide antibacterial activity Some Schiff bases of pyrazole and 4-amino antipyrine have been synthesized. The antibacterial screening of these synthesized compounds was done in dimethyl forma-mide against four Gram positive bacteria viz. Bacillus cereus, Staphylococcus aureus, Staphylococcus epidermidids and Micrococcus luteus, and three Gram negative bacteria viz. Proteus mirabilis, Escherichia coli and Klebsiella aerogenes. It is observed that in comparison to Schiff bases of 4-amino antipyrine, pyrazole Schiff bases are better for inhibition for these selected Gram positive and Gram negative bacterial strains.info:eu-repo/semantics/openAccessDepartamento de Farmácia, Facultad de Ciencias, Universidade Nacional da ColombiaRevista Colombiana de Ciencias Químico - Farmacéuticas v.45 n.2 20162016-05-01info:eu-repo/semantics/articletext/htmlhttp://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0034-74182016000200002en10.15446/rcciquifa.v45n2.59936
institution SCIELO
collection OJS
country Colombia
countrycode CO
component Revista
access En linea
databasecode rev-scielo-co
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Baluja,Shipra
Chanda,Sumitra
spellingShingle Baluja,Shipra
Chanda,Sumitra
Synthesis, characterization and antibacterial screening of some Schiff bases derived from pyrazole and 4-amino antipyrine
author_facet Baluja,Shipra
Chanda,Sumitra
author_sort Baluja,Shipra
title Synthesis, characterization and antibacterial screening of some Schiff bases derived from pyrazole and 4-amino antipyrine
title_short Synthesis, characterization and antibacterial screening of some Schiff bases derived from pyrazole and 4-amino antipyrine
title_full Synthesis, characterization and antibacterial screening of some Schiff bases derived from pyrazole and 4-amino antipyrine
title_fullStr Synthesis, characterization and antibacterial screening of some Schiff bases derived from pyrazole and 4-amino antipyrine
title_full_unstemmed Synthesis, characterization and antibacterial screening of some Schiff bases derived from pyrazole and 4-amino antipyrine
title_sort synthesis, characterization and antibacterial screening of some schiff bases derived from pyrazole and 4-amino antipyrine
description Some Schiff bases of pyrazole and 4-amino antipyrine have been synthesized. The antibacterial screening of these synthesized compounds was done in dimethyl forma-mide against four Gram positive bacteria viz. Bacillus cereus, Staphylococcus aureus, Staphylococcus epidermidids and Micrococcus luteus, and three Gram negative bacteria viz. Proteus mirabilis, Escherichia coli and Klebsiella aerogenes. It is observed that in comparison to Schiff bases of 4-amino antipyrine, pyrazole Schiff bases are better for inhibition for these selected Gram positive and Gram negative bacterial strains.
publisher Departamento de Farmácia, Facultad de Ciencias, Universidade Nacional da Colombia
publishDate 2016
url http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0034-74182016000200002
work_keys_str_mv AT balujashipra synthesischaracterizationandantibacterialscreeningofsomeschiffbasesderivedfrompyrazoleand4aminoantipyrine
AT chandasumitra synthesischaracterizationandantibacterialscreeningofsomeschiffbasesderivedfrompyrazoleand4aminoantipyrine
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