Cardiovascular adverse events associated with oral antineoplastic therapy

Cardiovascular adverse events associated with oral antineoplastic therapy

ABSTRACT Objective: To identify in the literature the cardiovascular adverse events resulting from oral antineoplastic therapy. Method: Integrative review of the literature through the SCOPUS, Scientific Electronic Library Online (SciELO), Cumulative Index to Nursing and Allied Health Literature (CINAHL), Medical Literature Analysis and Retrieval System Online (MEDLINE) databases. The antineoplastic, cardiotoxicity, cardiovascular system and adverse reaction descriptors were used in Portuguese, English and Spanish. We selected 23 articles published between 1985 and 2015. Results: Twenty studies were related to cardiac events and eleven to peripheral vascular events. The most frequent adverse cardiac events were reduced left ventricular ejection fraction, myocardial infarction, changes in the electrocardiogram, heart failure and angina, whereas peripheral vascular events were hypertension and thromboembolism. Conclusion: Oral antineoplastic therapy is associated with different adverse events, including cardiac and peripheral vascular events.

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Main Authors: Silva,Jacqueline Mota da, Lima,Beatriz da Silva, Araújo,Thelma Leite de, Lima,Francisca Elisângela Teixeira, Cunha,Gilmara Holanda da
Format: Digital revista
Language:English
Published: Associação Brasileira de Enfermagem 2018
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-71672018000502561
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spelling oai:scielo:S0034-716720180005025612018-10-03Cardiovascular adverse events associated with oral antineoplastic therapySilva,Jacqueline Mota daLima,Beatriz da SilvaAraújo,Thelma Leite deLima,Francisca Elisângela TeixeiraCunha,Gilmara Holanda da Antineoplastic Agents Adverse Effects Cardiotoxicity Cardiovascular System Review ABSTRACT Objective: To identify in the literature the cardiovascular adverse events resulting from oral antineoplastic therapy. Method: Integrative review of the literature through the SCOPUS, Scientific Electronic Library Online (SciELO), Cumulative Index to Nursing and Allied Health Literature (CINAHL), Medical Literature Analysis and Retrieval System Online (MEDLINE) databases. The antineoplastic, cardiotoxicity, cardiovascular system and adverse reaction descriptors were used in Portuguese, English and Spanish. We selected 23 articles published between 1985 and 2015. Results: Twenty studies were related to cardiac events and eleven to peripheral vascular events. The most frequent adverse cardiac events were reduced left ventricular ejection fraction, myocardial infarction, changes in the electrocardiogram, heart failure and angina, whereas peripheral vascular events were hypertension and thromboembolism. Conclusion: Oral antineoplastic therapy is associated with different adverse events, including cardiac and peripheral vascular events.info:eu-repo/semantics/openAccessAssociação Brasileira de EnfermagemRevista Brasileira de Enfermagem v.71 n.5 20182018-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-71672018000502561en10.1590/0034-7167-2017-0450
institution SCIELO
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country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Silva,Jacqueline Mota da
Lima,Beatriz da Silva
Araújo,Thelma Leite de
Lima,Francisca Elisângela Teixeira
Cunha,Gilmara Holanda da
spellingShingle Silva,Jacqueline Mota da
Lima,Beatriz da Silva
Araújo,Thelma Leite de
Lima,Francisca Elisângela Teixeira
Cunha,Gilmara Holanda da
Cardiovascular adverse events associated with oral antineoplastic therapy
author_facet Silva,Jacqueline Mota da
Lima,Beatriz da Silva
Araújo,Thelma Leite de
Lima,Francisca Elisângela Teixeira
Cunha,Gilmara Holanda da
author_sort Silva,Jacqueline Mota da
title Cardiovascular adverse events associated with oral antineoplastic therapy
title_short Cardiovascular adverse events associated with oral antineoplastic therapy
title_full Cardiovascular adverse events associated with oral antineoplastic therapy
title_fullStr Cardiovascular adverse events associated with oral antineoplastic therapy
title_full_unstemmed Cardiovascular adverse events associated with oral antineoplastic therapy
title_sort cardiovascular adverse events associated with oral antineoplastic therapy
description ABSTRACT Objective: To identify in the literature the cardiovascular adverse events resulting from oral antineoplastic therapy. Method: Integrative review of the literature through the SCOPUS, Scientific Electronic Library Online (SciELO), Cumulative Index to Nursing and Allied Health Literature (CINAHL), Medical Literature Analysis and Retrieval System Online (MEDLINE) databases. The antineoplastic, cardiotoxicity, cardiovascular system and adverse reaction descriptors were used in Portuguese, English and Spanish. We selected 23 articles published between 1985 and 2015. Results: Twenty studies were related to cardiac events and eleven to peripheral vascular events. The most frequent adverse cardiac events were reduced left ventricular ejection fraction, myocardial infarction, changes in the electrocardiogram, heart failure and angina, whereas peripheral vascular events were hypertension and thromboembolism. Conclusion: Oral antineoplastic therapy is associated with different adverse events, including cardiac and peripheral vascular events.
publisher Associação Brasileira de Enfermagem
publishDate 2018
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-71672018000502561
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