Oxytocin in cesarean-sections. What's new?

Abstract Oxytocin is the uterotonic agent of choice in the prevention and treatment of postpartum uterine atony. Nevertheless, there is no consensus on the optimal dose and rate for use in cesarean sections. The use of high bolus doses (e.g., 10 IU of oxytocin) can determine deleterious cardiovascular changes for the patient, especially in situations of hypovolemia or low cardiac reserve. Furthermore, high doses of oxytocin for prolonged periods may lead to desensitization of oxytocin receptors in myometrium, resulting in clinical inefficiency.

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Bibliographic Details
Main Authors: Yamaguchi,Eduardo Tsuyoshi, Siaulys,Mônica Maria, Torres,Marcelo Luis Abramides
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Anestesiologia 2016
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-70942016000400402
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