Adverse perinatal outcomes for advanced maternal age: a cross-sectional study of Brazilian births

ABSTRACT OBJECTIVES: To investigate the risk of adverse perinatal outcomes in women aged ≥41 years relatively to those aged 21-34. METHODS: Approximately 8.5 million records of singleton births in Brazilian hospitals in the period 2004-2009 were investigated. Odds ratios were estimated for preterm and post-term births, for low Apgar scores at 1 min and at 5 min, for asphyxia, for low birth weight, and for macrosomia. RESULTS: For pregnant women ≥41, increased risks were identified for preterm births, for post-term births (except for primiparous women with schooling ≥12 years), and for low birth weight. When comparing older vs. younger women, higher educational levels ensure similar risks of low Apgar score at 1 min (for primiparous mothers and term births), of low Apgar score at 5 min (for term births), of macrosomia (for non-primiparous women), and of asphyxia. CONCLUSION: As a rule, older mothers are at higher risk of adverse perinatal outcomes, which, however, may be mitigated or eliminated, depending on gestational age, parity, and, especially, on the education level of the pregnant woman.

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Main Authors: Almeida,Núbia Karla O., Almeida,Renan M.V.R., Pedreira,Carlos Eduardo
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Pediatria 2015
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572015000500493
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spelling oai:scielo:S0021-755720150005004932015-11-17Adverse perinatal outcomes for advanced maternal age: a cross-sectional study of Brazilian birthsAlmeida,Núbia Karla O.Almeida,Renan M.V.R.Pedreira,Carlos Eduardo Maternal age Adverse perinatal outcome Risk factors Educational level ABSTRACT OBJECTIVES: To investigate the risk of adverse perinatal outcomes in women aged ≥41 years relatively to those aged 21-34. METHODS: Approximately 8.5 million records of singleton births in Brazilian hospitals in the period 2004-2009 were investigated. Odds ratios were estimated for preterm and post-term births, for low Apgar scores at 1 min and at 5 min, for asphyxia, for low birth weight, and for macrosomia. RESULTS: For pregnant women ≥41, increased risks were identified for preterm births, for post-term births (except for primiparous women with schooling ≥12 years), and for low birth weight. When comparing older vs. younger women, higher educational levels ensure similar risks of low Apgar score at 1 min (for primiparous mothers and term births), of low Apgar score at 5 min (for term births), of macrosomia (for non-primiparous women), and of asphyxia. CONCLUSION: As a rule, older mothers are at higher risk of adverse perinatal outcomes, which, however, may be mitigated or eliminated, depending on gestational age, parity, and, especially, on the education level of the pregnant woman.info:eu-repo/semantics/openAccessSociedade Brasileira de PediatriaJornal de Pediatria v.91 n.5 20152015-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572015000500493en10.1016/j.jped.2014.12.002
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country Brasil
countrycode BR
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region America del Sur
libraryname SciELO
language English
format Digital
author Almeida,Núbia Karla O.
Almeida,Renan M.V.R.
Pedreira,Carlos Eduardo
spellingShingle Almeida,Núbia Karla O.
Almeida,Renan M.V.R.
Pedreira,Carlos Eduardo
Adverse perinatal outcomes for advanced maternal age: a cross-sectional study of Brazilian births
author_facet Almeida,Núbia Karla O.
Almeida,Renan M.V.R.
Pedreira,Carlos Eduardo
author_sort Almeida,Núbia Karla O.
title Adverse perinatal outcomes for advanced maternal age: a cross-sectional study of Brazilian births
title_short Adverse perinatal outcomes for advanced maternal age: a cross-sectional study of Brazilian births
title_full Adverse perinatal outcomes for advanced maternal age: a cross-sectional study of Brazilian births
title_fullStr Adverse perinatal outcomes for advanced maternal age: a cross-sectional study of Brazilian births
title_full_unstemmed Adverse perinatal outcomes for advanced maternal age: a cross-sectional study of Brazilian births
title_sort adverse perinatal outcomes for advanced maternal age: a cross-sectional study of brazilian births
description ABSTRACT OBJECTIVES: To investigate the risk of adverse perinatal outcomes in women aged ≥41 years relatively to those aged 21-34. METHODS: Approximately 8.5 million records of singleton births in Brazilian hospitals in the period 2004-2009 were investigated. Odds ratios were estimated for preterm and post-term births, for low Apgar scores at 1 min and at 5 min, for asphyxia, for low birth weight, and for macrosomia. RESULTS: For pregnant women ≥41, increased risks were identified for preterm births, for post-term births (except for primiparous women with schooling ≥12 years), and for low birth weight. When comparing older vs. younger women, higher educational levels ensure similar risks of low Apgar score at 1 min (for primiparous mothers and term births), of low Apgar score at 5 min (for term births), of macrosomia (for non-primiparous women), and of asphyxia. CONCLUSION: As a rule, older mothers are at higher risk of adverse perinatal outcomes, which, however, may be mitigated or eliminated, depending on gestational age, parity, and, especially, on the education level of the pregnant woman.
publisher Sociedade Brasileira de Pediatria
publishDate 2015
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572015000500493
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