Morphea: a practical review of its diagnosis, classification and treatment

Morphea: a practical review of its diagnosis, classification and treatment

Morphea, or localized scleroderma, is a rare disease of the connective tissue that manifests itself with localized sclerosis of the skin and, in some cases, with extracutaneous manifestations. Its etiology is not fully understood, but it is believed that there is genetic predisposition, in addition to environmental triggering factors. Classification of the disease is not simple due to its multiple presentations; however, it is useful in order to define the treatment, which should be individualized and started early to avoid cosmetic and functional complications. In this review, we summarize the most important practical aspects of the classification, diagnostic methods and evaluation of morphea activity, as well as available therapeutic options, with an emphasis on existing clinical evidence regarding their efficacy and safety.

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Main Authors: Rodríguez-Salgado,Pamela, García-Romero,María Teresa
Format: Digital revista
Language:English
Published: Academia Nacional de Medicina de México A.C. 2019
Online Access:http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0016-38132019000500483
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spelling oai:scielo:S0016-381320190005004832021-06-30Morphea: a practical review of its diagnosis, classification and treatmentRodríguez-Salgado,PamelaGarcía-Romero,María Teresa Morphea Localized scleroderma Lichen sclerosus et atrophicus Morphea, or localized scleroderma, is a rare disease of the connective tissue that manifests itself with localized sclerosis of the skin and, in some cases, with extracutaneous manifestations. Its etiology is not fully understood, but it is believed that there is genetic predisposition, in addition to environmental triggering factors. Classification of the disease is not simple due to its multiple presentations; however, it is useful in order to define the treatment, which should be individualized and started early to avoid cosmetic and functional complications. In this review, we summarize the most important practical aspects of the classification, diagnostic methods and evaluation of morphea activity, as well as available therapeutic options, with an emphasis on existing clinical evidence regarding their efficacy and safety.info:eu-repo/semantics/openAccessAcademia Nacional de Medicina de México A.C.Gaceta médica de México v.155 n.5 20192019-10-01info:eu-repo/semantics/articletext/htmlhttp://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0016-38132019000500483en10.24875/gmm.m20000336
institution SCIELO
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country México
countrycode MX
component Revista
access En linea
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tag revista
region America del Norte
libraryname SciELO
language English
format Digital
author Rodríguez-Salgado,Pamela
García-Romero,María Teresa
spellingShingle Rodríguez-Salgado,Pamela
García-Romero,María Teresa
Morphea: a practical review of its diagnosis, classification and treatment
author_facet Rodríguez-Salgado,Pamela
García-Romero,María Teresa
author_sort Rodríguez-Salgado,Pamela
title Morphea: a practical review of its diagnosis, classification and treatment
title_short Morphea: a practical review of its diagnosis, classification and treatment
title_full Morphea: a practical review of its diagnosis, classification and treatment
title_fullStr Morphea: a practical review of its diagnosis, classification and treatment
title_full_unstemmed Morphea: a practical review of its diagnosis, classification and treatment
title_sort morphea: a practical review of its diagnosis, classification and treatment
description Morphea, or localized scleroderma, is a rare disease of the connective tissue that manifests itself with localized sclerosis of the skin and, in some cases, with extracutaneous manifestations. Its etiology is not fully understood, but it is believed that there is genetic predisposition, in addition to environmental triggering factors. Classification of the disease is not simple due to its multiple presentations; however, it is useful in order to define the treatment, which should be individualized and started early to avoid cosmetic and functional complications. In this review, we summarize the most important practical aspects of the classification, diagnostic methods and evaluation of morphea activity, as well as available therapeutic options, with an emphasis on existing clinical evidence regarding their efficacy and safety.
publisher Academia Nacional de Medicina de México A.C.
publishDate 2019
url http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0016-38132019000500483
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